-
公开(公告)号：US20130210069A1
公开(公告)日：2013-08-15
申请号：US13881065
申请日：2011-10-28
申请人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth
发明人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth
IPC分类号： C12Q1/02
摘要： A biological sterilization indicator (BI) system and method. The system can include a BI and a reading apparatus comprising a well. The BI can include a housing, which can include a first portion, and a second portion movable between a first “unactivated” position and a second “activated” position. The BI can further include a frangible container containing a liquid and dimensioned to be positioned in the housing. The reading apparatus can be configured to detect activation of the biological sterilization indicator, for example, by detecting that the second portion is in the second position, and/or by detecting that the liquid from the frangible container is present in a specific chamber of the biological sterilization indicator. The method can include positioning the BI in the well of the reading apparatus and detecting activation, for example, by detecting one or more of the above conditions.
摘要翻译： 一种生物灭菌指标（BI）系统及方法。 该系统可以包括BI和包括井的读取装置。 BI可以包括壳体，其可以包括第一部分，以及可在第一“未激活”位置和第二“激活”位置之间移动的第二部分。 BI还可以包括容纳液体并且尺寸设置在壳体中的易碎容器。 读取装置可以被配置为检测生物灭菌指示器的激活，例如通过检测第二部分处于第二位置，和/或通过检测来自易碎容器的液体存在于 生物灭菌指标。 该方法可以包括将BI定位在读取装置的阱中并检测激活，例如通过检测上述一个或多个条件。
-
公开(公告)号：US09410180B2
公开(公告)日：2016-08-09
申请号：US13821647
申请日：2011-10-28
申请人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth , Kaileen Chen
发明人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth , Kaileen Chen
摘要： A biological sterilization indicator (BI) system and method. The system can include a BI and a reading apparatus comprising a well. The BI can include a housing, which can include a first portion, and a second portion movable between a first “unactivated” position and a second “activated” position. The reading apparatus can detect at least one of (i) when the well is empty; (ii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the first position, and (iii) when the biological sterilization indicator is positioned in the well with the second portion of the housing in the second position. The method can include detecting at least one of the above conditions, which can be used to detect an activation status of the biological sterilization indicator.
摘要翻译： 一种生物灭菌指标（BI）系统及方法。 该系统可以包括BI和包括井的读取装置。 BI可以包括壳体，其可以包括第一部分，以及可在第一“未激活”位置和第二“激活”位置之间移动的第二部分。 读取装置可以检测（i）当井是空的时候的至少一个; （ii）当生物灭菌指示器位于井中时，壳体的第二部分处于第一位置，以及（iii）当生物灭菌指示器位于井中时，壳体的第二部分位于第二位置 。 该方法可以包括检测可用于检测生物灭菌指示剂的活化状态的上述条件中的至少一个。
-
公开(公告)号：US08802392B2
公开(公告)日：2014-08-12
申请号：US13825881
申请日：2011-10-28
申请人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Kurt J. Halverson , Brian R. Engel
发明人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Kurt J. Halverson , Brian R. Engel
IPC分类号： C12Q1/22
摘要： The present invention provides method of detecting a predetermined biological activity. The method includes using an aqueous mixture comprising a first indicator reagent with a first absorption spectrum and a second indicator reagent. The second indicator reagent is converted by the predetermined biological activity to a second biological derivative with a second emission spectrum. The first absorbance spectrum includes detectable absorbance in at least a portion of wavelengths present in the second emission spectrum. The first indicator reagent is received and concentrated from an aqueous liquid by a substrate, facilitating the detection of the second biological derivative.
摘要翻译： 本发明提供了检测预定生物活性的方法。 该方法包括使用包含具有第一吸收光谱的第一指示剂和第二指示剂试剂的含水混合物。 第二指示剂通过预定的生物活性转化为具有第二发射光谱的第二生物衍生物。 第一吸收光谱包括在第二发射光谱中存在的波长的至少一部分中的可检测吸光度。 第一指示剂被含水液体接收并通过底物浓缩，便于检测第二生物衍生物。
-
公开(公告)号：US20130210067A1
公开(公告)日：2013-08-15
申请号：US13825881
申请日：2011-10-28
申请人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Kurt J. Halverson , Brian R. Engel
发明人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Kurt J. Halverson , Brian R. Engel
IPC分类号： G01N21/64
摘要： The present invention provides method of detecting a predetermined biological activity. The method includes using an aqueous mixture comprising a first indicator reagent with a first absorption spectrum and a second indicator reagent. The second indicator reagent is converted by the predetermined biological activity to a second biological derivative with a second emission spectrum. The first absorbance spectrum includes detectable absorbance in at least a portion of wavelengths present in the second emission spectrum. The first indicator reagent is received and concentrated from an aqueous liquid by a substrate, facilitating the detection of the second biological derivative.
摘要翻译： 本发明提供了检测预定生物活性的方法。 该方法包括使用包含具有第一吸收光谱的第一指示剂和第二指示剂试剂的含水混合物。 第二指示剂通过预定的生物活性转化为具有第二发射光谱的第二生物衍生物。 第一吸收光谱包括在第二发射光谱中存在的波长的至少一部分中的可检测吸光度。 第一指示剂被含水液体接收并通过底物浓缩，便于检测第二生物衍生物。
-
公开(公告)号：US09145573B2
公开(公告)日：2015-09-29
申请号：US13881065
申请日：2011-10-28
申请人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth
发明人： Jeffrey C. Pederson , Sailaja Chandrapati , Bryan S. Behun , Barry W. Robole , Leroy J. Longworth
摘要： A biological sterilization indicator (BI) system and method. The system can include a BI and a reading apparatus comprising a well. The BI can include a housing, which can include a first portion, and a second portion movable between a first “unactivated” position and a second “activated” position. The BI can further include a frangible container containing a liquid and dimensioned to be positioned in the housing. The reading apparatus can be configured to detect activation of the biological sterilization indicator, for example, by detecting that the second portion is in the second position, and/or by detecting that the liquid from the frangible container is present in a specific chamber of the biological sterilization indicator. The method can include positioning the BI in the well of the reading apparatus and detecting activation, for example, by detecting one or more of the above conditions.
摘要翻译： 一种生物灭菌指标（BI）系统及方法。 该系统可以包括BI和包括井的读取装置。 BI可以包括壳体，其可以包括第一部分，以及可在第一“未激活”位置和第二“激活”位置之间移动的第二部分。 BI还可以包括容纳液体并且尺寸设置在壳体中的易碎容器。 读取装置可以被配置为检测生物灭菌指示器的激活，例如通过检测第二部分处于第二位置，和/或通过检测来自易碎容器的液体存在于 生物灭菌指标。 该方法可以包括将BI定位在读取装置的阱中并检测激活，例如通过检测上述一个或多个条件。
-
公开(公告)号：US20130210048A1
公开(公告)日：2013-08-15
申请号：US13825143
申请日：2011-10-28
摘要： A method of detecting a biological activity is provided. The method includes contacting; in a liquid medium selected to facilitate a predetermined biological activity; a sample, an indicator reagent, and a substrate that receives and concentrates a biological derivative of the indicator reagent. The method further includes observing a portion of the substrate to detect the biological derivative. The method can be used to detect the presence or absence of a target cell.
摘要翻译： 提供了检测生物活性的方法。 该方法包括接触; 在选择用于促进预定生物活性的液体介质中; 样品，指示剂试剂和接收并浓缩指示剂试剂的生物衍生物的底物。 该方法还包括观察基底的一部分以检测生物衍生物。 该方法可用于检测靶细胞的存在或不存在。
-
公开(公告)号：US08647574B2
公开(公告)日：2014-02-11
申请号：US12743252
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
发明人： Kurt J. Halverson , Stephen C. P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
IPC分类号： G01N15/06
CPC分类号： G01N1/38 , G01N1/4077 , G01N2001/4088
摘要： A system and method for preparing and collecting samples for analyte testing. The system can include a sample preparation system and a sample collection system coupled to the sample preparation system. The sample preparation system can include at least one of a deformable self-supporting receptacle comprising a reservoir and a freestanding receptacle comprising a reservoir. The reservoir can be adapted to contain a liquid composition. The sample collection system can be positioned in fluid communication with a reservoir of the sample preparation system, and can be adapted to capture an analyte of interest. The method can include providing a fluid path defined at least partially by the sample preparation system and the sample collection system, positioning the liquid composition in a reservoir of the sample preparation system, and moving at least a portion of the liquid composition in the fluid path to the sample collection system.
摘要翻译： 用于制备和收集样品用于分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品收集系统。 样品制备系统可以包括可变形的自支撑容器中的至少一个，其包括储存器和包括储存器的独立容器。 储存器可以适于容纳液体组合物。 样品收集系统可以定位成与样品制备系统的储存器流体连通，并且可以适于捕获感兴趣的分析物。 该方法可以包括提供至少部分地由样品制备系统和样品收集系统限定的流体路径，将液体组合物定位在样品制备系统的储存器中，并且将至少一部分液体组合物移动到流体路径 到采样系统。
-
公开(公告)号：US20100248215A1
公开(公告)日：2010-09-30
申请号：US12743449
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
发明人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
CPC分类号： G01N1/38
摘要： A system and method for preparing and delivering samples for analyte testing. The system can include a sample preparation system and a sample delivery system coupled to the sample preparation system. The sample preparation system can include a deformable self-supporting receptacle comprising a reservoir adapted to contain a liquid composition comprising a source and a diluent. The sample delivery system can include a valve positioned in fluid communication with the reservoir and adapted to control the removal of a sample from the sample preparation system. The method can include applying pressure to the deformable self-supporting receptacle to remove a sample from the sample preparation system via the sample delivery system.
摘要翻译： 用于制备和递送样品以进行分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品递送系统。 样品制备系统可以包括可变形的自支撑容器，其包括适于容纳包含源和稀释剂的液体组合物的储存器。 样品输送系统可以包括定位成与储存器流体连通的阀，并适于控制样品从样品制备系统中的去除。 该方法可以包括向可变形的自支撑容器施加压力，以经由样品输送系统从样品制备系统移除样品。
-
公开(公告)号：US20100273162A1
公开(公告)日：2010-10-28
申请号：US12676613
申请日：2008-10-15
申请人： Sailaja Chandrapati
发明人： Sailaja Chandrapati
CPC分类号： C12Q1/10 , C12Q1/14 , Y02A50/451
摘要： Methods for rapidly detecting Enterobacteriaceae and Micrococcaceae microorganisms utilizing non-amplified nucleic acids, acridiniu labeled ONA probes, and selective growth media are described, particularly for specific microbial species related to the food science industry and public health. Articles of manufacture that include reagents for detecting multiple microorganisms simultaneously are also described.
摘要翻译： 描述了利用非扩增核酸，acridiniu标记的ONA探针和选择性生长培养基快速检测肠杆菌科和微球菌微生物的方法，特别是与食品科学工业和公共卫生相关的特定微生物物种。 还描述了包括用于同时检测多种微生物的试剂的制造方法。
-
公开(公告)号：US07468272B2
公开(公告)日：2008-12-23
申请号：US10967394
申请日：2004-10-18
IPC分类号： C12N1/34
CPC分类号： G01N33/521 , C12Q1/04 , C12Q1/22 , C12Q2326/00 , C12Q2334/00 , C12Q2337/00
摘要： A biological soil detector and a method for detecting bio soil are provided. The biological soil detector has a solid support member; a specific indicator immobilized on the solid support member, the specific indicator having a material sensitive to the presence of blood; and the solid support and specific indicator positioned within or on a retaining member to readily contact a liquid that has been used to contact a surface. In the method for detecting bio soil, the method includes the following steps: contacting the surface with a liquid; after the liquid has contacted the surface, contacting the liquid with the solid support member and the specific indicator of the detector described herein; and inspecting the solid support member for a detectable response to determine whether the specific indicator has interacted with biological soil.
摘要翻译： 提供了一种生物土壤探测器和一种检测生物土壤的方法。 生物土壤探测器具有固体支撑构件; 固定在固体支持体上的特异性指示物，特异性指示剂具有对血液存在敏感的物质; 并且固体支持物和特定指示剂位于保持构件内或上，以容易地接触已经用于接触表面的液体。 在生物土壤检测方法中，该方法包括以下步骤：将表面与液体接触; 在液体接触表面之后，使液体与固体支撑构件和本文所述的检测器的特定指示剂接触; 并检查固体支持构件的可检测响应，以确定特定指标是否与生物土壤相互作用。
-
-
-
-
-
-
-
-
-
搜索结果
34 条记录 (耗时 0.028 秒)
