公开(公告)号：US20050096497A1

公开(公告)日：2005-05-05

申请号：US10698216

申请日：2003-10-31

Applicant: Martin Gerber ,  Warren Starkebaum ,  John Swoyer

Inventor： Martin Gerber ,  Warren Starkebaum ,  John Swoyer

IPC: A61F2/00 ,  A61L31/14 ,  A61F2/02

CPC classification number: A61F2/0036 ,  A61L31/145

Abstract: In general, the invention is directed to treatment of fecal incontinence by the implantation of one or more bulking prostheses proximate to an anal sphincter. These bulking prostheses, which may include biocompatible hydrogel, are inserted into the tissue near the anus through a small opening in the mucosa. When inserted, the bulking prostheses are in a miniature state. Upon introduction into the body, the devices enter an enlarged state. In their enlarged state, the bulking prostheses supply extra bulk to the tissues proximate to the anal sphincters. With the extra bulk, the patient can exercise voluntary control over the external sphincter to close the anus and maintain fecal continence.

Abstract translation: 通常，本发明涉及通过植入靠近肛门括约肌的一个或多个膨胀假体来治疗大便失禁。 这些膨胀假体可以包括生物相容的水凝胶，通过粘膜中的小开口插入到肛门附近的组织中。 当插入时，膨胀假体处于微型状态。 引入身体后，设备进入放大状态。 在扩大的状态下，膨胀假体向靠近肛门括约肌的组织提供额外的体积。 随着额外的体积，患者可以对外括约肌进行自愿控制以闭合肛门并维持粪便的排列。

公开(公告)号：US20050060014A1

公开(公告)日：2005-03-17

申请号：US10833761

申请日：2004-04-28

Applicant: John Swoyer ,  Keith Carlton ,  Martin Gerber ,  George Mamo ,  Michele Spinelli ,  Steven Hartle

Inventor： John Swoyer ,  Keith Carlton ,  Martin Gerber ,  George Mamo ,  Michele Spinelli ,  Steven Hartle

IPC: A61N1/05

CPC classification number: A61N1/0558 ,  A61N1/0551

Abstract: An implantable medical electrical lead particularly for stimulation of the sacral nerves comprises a lead body extending between a distal end and a proximal end, and the distal end having at least one electrode of an electrode array extending longitudinally from the distal end toward the proximal end. The lead body at its proximal end may be coupled to a pulse generator, additional intermediate wiring, or other stimulation device. A fixation mechanism is formed on or integrally with the lead body proximal to the electrode array that is adapted to be implanted in and engage subcutaneous tissue, particularly muscle tissue, to inhibit axial movement of the lead body and dislodgement of the stimulation electrodes. The fixation mechanism comprises a M tine elements arrayed in a tine element array along a segment of the lead proximal to the stimulation electrode array. Each tine element comprises at least N flexible, pliant, tines, each tine having a tine width and thickness and extending through a tine length from an attached tine end to a free tine end. The attached tine end is attached to the lead body from a tine attachment site and supports the tine extending outwardly of the lead body and proximally toward the lead proximal end. The M×N tines are adapted to be folded inward against the lead body when fitted into and constrained by the lumen of an introducer such that the tine free ends of more distal tines of more distal tine elements are urged toward or alongside the attached tine ends of the adjacent more proximal tines of more proximal tine elements, and the folded tines do not overlap one another.

Abstract translation: 特别是用于刺激骶神经的可植入医用电气引线包括在远端和近端之间延伸的引线体，并且远端具有从远端向近端纵向延伸的电极阵列的至少一个电极。 其近端的引线体可以耦合到脉冲发生器，附加的中间布线或其它刺激装置。 在与电极阵列接近的引线体上形成一体的固定机构，该固定机构适于被植入并接合皮下组织，特别是肌肉组织，以抑制引线体的轴向移动和刺激电极的移动。 固定机构包括沿着靠近刺激电极阵列的引线的段排列在齿元件阵列中的M元件。 每个齿元件包括至少N个柔性，柔韧的尖齿，每个齿具有齿的宽度和厚度并且延伸穿过齿长从附接的齿端延伸到游离齿端。 附着的尖端从齿附着位置附接到引线本体，并且支撑从引线主体向外延伸并向近端朝向引线近端的齿。 MxN齿适合于当插入导引器的内腔并被约束的引导体时向内折叠，使得更远端的尖齿元件的更远远的尖齿的齿自由端朝着或与其相连的齿端被推向 相邻的更接近的尖齿元件的近端齿，并且折叠的齿不相互重叠。

公开(公告)号：US09089693B2

公开(公告)日：2015-07-28

申请号：US13537341

申请日：2012-06-29

Applicant: John Swoyer ,  James Finley ,  Lawrence Kane

Inventor： John Swoyer ,  James Finley ,  Lawrence Kane

IPC: A61N1/05 ,  A61N1/36

CPC classification number: A61N1/05 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36053

Abstract: A therapy assembly configured for at least partial insertion in a living body. At least one fixation structure is attached to the therapy delivery element proximate the electrodes. The fixation structure is configured to collapse radially inward and wrap circumferentially around the therapy delivery element to a collapsed configuration when inserted into a lumen of an introducer. The fixation structures deploy to a deployed configuration when the introducer is retracted. The fixation structure includes major surfaces generally parallel with, and extending radially outward from, a central axis of the therapy delivery element, proximal edge surface oriented toward the proximal end, and a distal edge surface oriented toward the distal end. The proximal and distal edge surfaces provide generally symmetrical resistance to displacement of the therapy delivery element within the living body in either a proximal direction or a distal direction along the central axis.

Abstract translation: 一种治疗组件，其构造成用于至少部分地插入生物体内。 至少一个固定结构附接到靠近电极的治疗递送元件。 固定结构构造成当插入到导引器的内腔中时，径向向内折叠并围绕治疗递送元件周向地折叠成折叠构造。 当导引器缩回时，固定结构部署到展开配置。 固定结构包括与治疗递送元件的中心轴大致平行并且从其径向向外延伸的主表面，朝向近端定向的近端边缘表面和朝向远端定向的远端边缘表面。 近端和远端边缘表面提供对沿着中心轴线的近端方向或远端方向上的治疗递送元件在生物体内的移位的大致对称的阻力。

公开(公告)号：US20140046413A1

公开(公告)日：2014-02-13

申请号：US13571987

申请日：2012-08-10

Applicant: LAWRENCE KANE ,  Elliot W. Bridgeman ,  John Swoyer

Inventor： LAWRENCE KANE ,  Elliot W. Bridgeman ,  John Swoyer

IPC: A61N1/05

CPC classification number: A61N1/0558 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00285 ,  A61F2/90 ,  A61N1/057 ,  A61N2001/058

Abstract: A therapy assembly configured for at least partial insertion in a living body. A plurality of fixation structures are disposed radially around the therapy delivery element proximate the electrodes. The fixation structures include wires having a diameter in a range between about 0.004 inches and about 0.020 inches. The wires have a first end attached to the therapy delivery element and a second end attached to a sliding member configured to slide along the therapy delivery element. The fixation structures are configured to collapse inward to a collapsed configuration when inserted into a lumen of an introducer and to deploy to a deployed configuration when the introducer is retracted. A fitting is located at proximal end of the introducer that releasably locks the therapy delivery element to the introducer, such that torque applied to the fitting is substantially transmitted to the distal end of the therapy assembly.

Abstract translation: 一种治疗组件，其构造成用于至少部分地插入生物体内。 多个固定结构被放置在靠近电极的治疗递送元件周围。 固定结构包括直径在约0.004英寸和约0.020英寸之间的直径的导线。 电线具有连接到治疗递送元件的第一端和附接到被配置为沿着治疗递送元件滑动的滑动构件的第二端。 固定结构构造成当插入导引器的内腔中时向内折叠成折叠构型，并且当导入器缩回时部署到展开构型。 导管器的近端处的配件位于可释放地将治疗递送元件锁定到导引器上，使得施加到配件的扭矩基本上传递到治疗组件的远端。

公开(公告)号：US08644953B1

公开(公告)日：2014-02-04

申请号：US13572081

申请日：2012-08-10

Applicant: James Finley ,  John Swoyer

Inventor： James Finley ,  John Swoyer

IPC: A61N1/00

CPC classification number: A61N1/0551 ,  A61N1/05 ,  Y10T29/49208 ,  Y10T29/4921

Abstract: A therapy delivery element configured for at least partial insertion in a living body. A braided structure surrounds the conductor assembly. A distal end of the braided structure is attached to an electrode assembly and a free floating proximal end is located near a connector assembly. An outer tubing surrounds the braided structure. The outer tubing includes a proximal end attached to the connector assembly and a distal end attached to the braided structure near the electrode assembly. A proximal tension force applied to the connector assembly acts substantially on the outer tubing and the conductor assembly and a proximal tension force applied to the free floating proximal end acts substantially on the braided structure.

Abstract translation: 治疗递送元件，其构造成用于至少部分地插入生物体。 编织结构围绕导体组件。 编织结构的远端附接到电极组件，并且自由浮动近端位于连接器组件附近。 外管围绕编织结构。 外管包括附接到连接器组件的近端和在电极组件附近附接到编织结构的远端。 施加到连接器组件的近侧张力基本上作用在外管和导体组件上，并且施加到自由浮动近端的近侧张力基本上作用在编织结构上。

公开(公告)号：US08560084B2

公开(公告)日：2013-10-15

申请号：US13220913

申请日：2011-08-30

Applicant: Jesse Geroy ,  John Swoyer

Inventor： Jesse Geroy ,  John Swoyer

IPC: A61N1/05

CPC classification number: A61N1/0551 ,  A61N1/05 ,  H01B7/048 ,  Y10T29/49169

Abstract: A biomedical conductor assembly adapted for at least partial insertion in a living body. The conductor assembly includes a plurality of the first electrical conductors each covered with an insulator and helically wound in a first direction to form an inner coil with a lumen. A plurality of second electrical conductors each including a plurality of un-insulated wires twisted in a ropelike configuration around a central axis to form a plurality of cables. Each cable is covered with an insulator and helically wound in a second opposite direction forming an outer coil in direct physical contact with the inner coil. The inner and outer coils are covered by an insulator. A method of making the conductor assembly and implanting a neurostimulation system is also disclosed.

公开(公告)号：US08437846B2

公开(公告)日：2013-05-07

申请号：US13046182

申请日：2011-03-11

Applicant: John Swoyer ,  Jesse Geroy ,  James Finley

Inventor： John Swoyer ,  Jesse Geroy ,  James Finley

IPC: A61N1/02

CPC classification number: A61N1/0558 ,  A61B17/0401

Abstract: A pre-sutured anchor including a deformable anchor sleeve with a lumen sized to receive the therapy delivery element. An outer surface of the anchor sleeve including one or more annular compression grooves oriented generally co-axial to the lumen. At least one compression member is located in a compression groove in an open configuration. The compression member includes at least one stop. A suture material pre-tied in a self-locking compression knot extends around each compression member. The suture material includes distal ends adapted to receive a tension force that is transmitted as a radial compression force to deform the compression members and substantially engage the stop in a compressed configuration. The anchor sleeve compressively engages the therapy delivery element in the compressed configuration.

Abstract translation: 一种预先缝合的锚，其包括可变形锚固套筒，其具有尺寸适于接收治疗递送元件的内腔。 锚定套筒的外表面包括一个或多个环形压缩槽，该环形压缩槽大致与内腔同轴。 至少一个压缩构件位于处于打开构型的压缩槽中。 压缩构件包括至少一个止挡件。 预先捆绑在自锁压缩结中的缝合材料围绕每个压缩构件延伸。 缝线材料包括适于接收作为径向压缩力传递的张力的远端，以使压缩构件变形并基本上以压缩构型接合止动件。 锚定套筒以压缩构型压缩地接合治疗递送元件。

公开(公告)号：US08019440B2

公开(公告)日：2011-09-13

申请号：US12029896

申请日：2008-02-12

Applicant: Scott Kokones ,  John Swoyer ,  Jesse Geroy

Inventor： Scott Kokones ,  John Swoyer ,  Jesse Geroy

IPC: A61N1/05

CPC classification number: A61N1/0539 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0551

Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.

Abstract translation: 在其上具有定向电极的引线。 还提供了具有定向电极的引线以及固定引脚以将电极固定到引线。 还提供了具有定向电极的引线，其中所有电极具有相同的表面积。 还提供了治疗条件和选择性刺激脑的区域如丘脑和小脑的方法。

公开(公告)号：US20090204193A1

公开(公告)日：2009-08-13

申请号：US12029896

申请日：2008-02-12

Applicant: Scott Kokones ,  John Swoyer ,  Jesse Geroy

Inventor： Scott Kokones ,  John Swoyer ,  Jesse Geroy

IPC: A61N1/05

CPC classification number: A61N1/0539 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0551

Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.

Abstract translation: 在其上具有定向电极的引线。 还提供了具有定向电极的引线以及固定引脚以将电极固定到引线。 还提供了具有定向电极的引线，其中所有电极具有相同的表面积。 还提供了治疗条件和选择性刺激脑的区域如丘脑和小脑的方法。

公开(公告)号：US20080021445A1

公开(公告)日：2008-01-24

申请号：US11833107

申请日：2007-08-02

Applicant: Ahmed Elmouelhi ,  Mark Christopherson ,  John Swoyer ,  Shahn Sage

Inventor： Ahmed Elmouelhi ,  Mark Christopherson ,  John Swoyer ,  Shahn Sage

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/1477 ,  A61B2017/00274 ,  A61B2018/00083 ,  A61B2018/00196 ,  A61B2018/00547 ,  A61B2018/00988 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1475

Abstract: A one-piece, single-use disposable device for transurethral needle ablation (TUNA) of prostate tissue to alleviate BPH is disclosed. The device may include a flexible catheter tip including a rigid core and a flexible tip. The device may also include a single use lockout to help ensure that the device is used to perform only one ablation procedure on a single patient. The device may further include a simplified needle deployment mechanism and/or an automatic needle retraction mechanism.

Abstract translation: 公开了一种用于经尿道针消融（TUNA）的前列腺组织以缓解BPH的单件式一次性一次性装置。 该装置可以包括柔性导管尖端，其包括刚性芯和柔性尖端。 该装置还可以包括单次使用锁定，以帮助确保该装置仅用于在单个患者上执行一个消融程序。 该装置还可以包括简化的针展开机构和/或自动针回缩机构。