公开(公告)号：US07094894B2

公开(公告)日：2006-08-22

申请号：US10513030

申请日：2003-04-30

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A01N43/90 ,  C07C69/618

CPC分类号： C07D487/04 ,  A01N43/90 ,  C07C69/65

摘要： Disclosed are a method for producing fungicidal triazolopyrimidine compounds, agents containing said compounds, and the use thereof for controlling harmful fungi. Also disclosed are triazolopyrimidines of formula (I), in which the substituents have the following meaning: L1 represents alkyl; L2 represents halogen; L3represents hydrogen or halogen; X represents halogen, cyano, alkyl, alkoxy, or haloalkoxy; R1, R2 represent hydrogen, alkyl, haloalkyl, cycloalkyl, alkenyl, alkadienyl, alkinyl, or cycloalkinyl, phenyl, naphthyl, or a five-unit to ten-unit saturated, partially unsaturated, or aromatic heterocycle containing one to four heteroatoms from the group O, N, or S, R1 and R2 can also form a five-unit or six-unit ring along with the nitrogen atom to which they are linked. Said ring can be interrupted and/or substituted by an atom from the group O, N, and S while R1 and/or R2 can be substituted according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing said compounds, and the use thereof for controlling harmful fungi

摘要翻译： 公开了生产杀真菌三唑并嘧啶化合物的方法，含有所述化合物的试剂及其用于控制​​有害真菌的用途。 还公开了式（I）的三唑并嘧啶，其中取代基具有以下含义：L 1表示烷基; L 2表示卤素; L 3表示氢或卤素; X表示卤素，氰基，烷基，烷氧基或卤代烷氧基; R 1，R 2代表氢，烷基，卤代烷基，环烷基，烯基，链二烯基，炔基或环炔基，苯基，萘基或五个单元至十个单元 饱和的，部分不饱和的或含有一至四个O，N或S杂原子的杂环，R 1和R 2也可以形成五单元或 六单元环与它们所连接的氮原子一起。 所述环可以被O，N和S基团的原子中断和/或取代，而R 1和/或R 2可以根据描述被取代 。 本发明还涉及用于生产所述化合物的方法和中间产物，含有所述化合物的试剂及其用于控制​​有害真菌的用途

公开(公告)号：US20050256138A1

公开(公告)日：2005-11-17

申请号：US10513030

申请日：2003-04-30

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewhr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Muller ,  Markus Gewhr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  C07C69/65 ,  C07D487/04 ,  A61K31/519

CPC分类号： C07D487/04 ,  A01N43/90 ,  C07C69/65

摘要： Disclosed are a method for producing fungicidal triazolopyrimidine compounds, agents containing said compounds, and the use thereof for controlling harmful fungi. Also disclosed are triazolopyrimidines of formula (1), in which the substituents have the following meaning: L1 represents alkyl; L2 represents halogen; L3represents hydrogen or halogen; X represents halogen, cyano, alkyl, alkoxy, or haloalkoxy; R1, R2 represent hydrogen, alkyl, haloalkyl, cycloalkyl, alkenyl, alkadienyl, alkinyl, or cycloalkinyl, phenyl, naphthyl, or a five-unit to ten-unit saturated, partially unsaturated, or aromatic heterocycle containing one to four heteroatoms from the group O, N, or S. R1 and R2 can also form a five-unit or six-unit ring along with the nitrogen atom to which they are linked. Said ring can be interrupted and/or substituted by an atom from the group O, N, and S while R1 and/or R2 can be substituted according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing said compounds, and the use thereof for controlling harmful fungi.

摘要翻译： 公开了生产杀真菌三唑并嘧啶化合物的方法，含有所述化合物的试剂及其用于控制​​有害真菌的用途。 还公开了式（1）的三唑并嘧啶，其中取代基具有以下含义：L 1表示烷基; L 2表示卤素; L 3表示氢或卤素; X表示卤素，氰基，烷基，烷氧基或卤代烷氧基; R 1，R 2代表氢，烷基，卤代烷基，环烷基，烯基，链二烯基，炔基或环炔基，苯基，萘基或五个单元至十个单元 饱和的，部分不饱和的或芳族杂环，其含有一至四个O，N或S的杂原子.R 1和R 2也可以形成五单元或 六单元环与它们所连接的氮原子一起。 所述环可以被O，N和S基团的原子中断和/或取代，而R 1和/或R 2可以根据描述被取代 。 本发明还涉及用于生产所述化合物的方法和中间产物，含有所述化合物的试剂及其用于控制​​有害真菌的用途。

公开(公告)号：US06855718B2

公开(公告)日：2005-02-15

申请号：US10416467

申请日：2001-11-09

申请人： Jordi Tormo i Blasco ,  Klaus Ditrich ,  Hubert Sauter ,  Oliver Cullmann ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Klaus Ditrich ,  Hubert Sauter ,  Oliver Cullmann ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  C07B53/00 ,  C07C209/62 ,  C07C211/03 ,  C07D487/04

CPC分类号： C07D487/04 ,  A01N43/90

摘要： A 7-(R)-Aminotriazolopyrimidines of formula I where the substituents and index are as defined below: R1 is hydrogen or methyl; R2 is methyl; R3 is C2-C10-alkyl, C1-C4-alkoxymethyl, C3-C10-cycloalkyl; Y is halogen, cyano, C1-C4-alkyl or C1-C4-alkoxy; where * is a center of chirality in the R configuration, processes for their preparation, compositions comprising them and their use for controlling harmful fungi.

摘要翻译： 式I的7-（R） - 氨基三唑并嘧啶，其中取代基和指数如下所定义：R 1是氢或甲基; R 2是甲基; R 3是C 2 -C 10 - 烷基，C 1 -C 4 - 烷氧基甲基，C 3 -C 10 - 环烷基; Y是卤素，氰基，C 1 -C 4 - 烷基或C 1 -C 4 - 烷氧基;其中*是R构型的手性中心，其制备方法，包含它们的组合物及其用途 用于控制有害真菌。

公开(公告)号：US06455515B2

公开(公告)日：2002-09-24

申请号：US09879902

申请日：2001-06-14

申请人： Andreas Gypser ,  Thomas Grote ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Oliver Cullmann ,  Markus Gewehr ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Bernd Müller ,  Hubert Sauter ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Andreas Gypser ,  Thomas Grote ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Oliver Cullmann ,  Markus Gewehr ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Bernd Müller ,  Hubert Sauter ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： A01N3740

CPC分类号： C07C255/66 ,  A01N37/40 ,  A01N37/46 ,  A01N47/20 ,  A01N47/30 ,  C07C251/86

摘要： Salicylohydrazide derivatives of the formula I in which the index and the substituents have the following meanings: X is halogen, NO2, cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to differ from each other if n is greater than 1; R1 is NO2, NH2 or NH—CO—A; A is hydrogen, alkyl, alkoxy, NH2, NHCH3 or N(CH3)2; R2 is hydrogen, cyano, alkyl, alkenyl, alkynyl, haloalkyl, alkoxy or alkylthio; it being possible for the hydrocarbon radicals to be unsubstituted or substituted, R3 is phenyl, naphthyl, cycloalkyl, 5-membered or 6-membered hetaryl or 5-membered or 6-membered heterocyclyl containing one to three N atoms and/or one O or S atom or one or two O and/or S atoms, the ring systems being unsubstituted or substituted; the preparation of these compounds, compositions comprising them, and their use for controlling harmful fungi.

摘要翻译： 指数和取代基具有以下含义的式Iin的磺酰肼衍生物：X是卤素，NO 2，氰基，烷基或烷氧基; m是0,1,2或3，取代基X可能与每个 另外，如果n大于1，则R1为NO2，NH2或NH-CO-A; A为氢，烷基，烷氧基，NH2，NHCH3或N（CH3）2; R2为氢，氰基，烷基，烯基，炔基， 卤代烷基，烷氧基或烷硫基;烃基可以是未取代的或取代的，R3是苯基，萘基，环烷基，含有1至3个N原子的5元或6元杂芳基或5元或6元杂环基 和/或一个O或S原子或一个或两个O和/或S原子，所述环系是未取代或取代的;这些化合物的制备，包含它们的组合物及其用于控制​​有害真菌的用途。

公开(公告)号：US07465735B2

公开(公告)日：2008-12-16

申请号：US10495280

申请日：2002-11-15

申请人： Andreas Gypser ,  Thomas Grote ,  Anja Schwögler ,  Joachim Rheinheimer ,  Frank Schieweck ,  Jordi Tormo i Blasco ,  Ingo Rose ,  Peter Schäfer ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Andreas Gypser ,  Thomas Grote ,  Anja Schwögler ,  Joachim Rheinheimer ,  Frank Schieweck ,  Jordi Tormo i Blasco ,  Ingo Rose ,  Peter Schäfer ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Müller ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D239/42 ,  C07D239/46 ,  C07D239/48 ,  C07D239/52 ,  C07D401/12 ,  C07D403/12 ,  A61K31/505 ,  A61K31/506 ,  A01N43/54

CPC分类号： C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/52 ,  C07D403/12

摘要： 5-Phenylpyrimidines, their preparation, compositions comprising them and their use 5-Phenylpyrimidines of the formula I in which the substituents and the index are as defined below: R1,R2 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, alkynyl or haloalkynyl, and R1 and R2 together with the nitrogen atom to which they are attached may also form a saturated or unsaturated ring which may be interrupted by an ether, thio, sulfoxyl or sulfonyl group and may be substituted by one to four groups Ra and/or Rb; R3 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy or alkenyloxy; R4 is hydrogen, halogen, cyano, hydroxyl, mercapto, azido, alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, alkylthio, alkenylthio, alkynylthio, haloalkylthio, —ON═CRaRb, —CRc═NORa, —NRcN═CRaRb, —NRaRb, —NRcNRaRb, —NORa, —NRcC(═NRc′)NRaRb, —NRcC(═O)NRaRb, —NRaC(═O)Rc, —NRaC(═NORc)Rc′, —OC(═O)Rc, —C(═NORc)NRaRb, —CRc(═NNRaRb), —C(═O)NRaRb or —C(═O)Rc; in which Ra, Rb and Rc are as defined in the description; X is halogen, alkyl, alkoxy or haloalkyl; and m is an integer from 1 to 5; processes for preparing these compounds, compositions comprising them and their use for controlling harmful fungi are described.

摘要翻译： 其中取代基和指数如下定义的式I的5-苯基嘧啶：R1，R2是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，卤代烯基，炔基或卤代炔基，R1和R2与氮原子一起 它们所连接的也可以形成可被醚，硫代，亚砜基或磺酰基中断的饱和或不饱和环，并且可以被一至四个基团R a和/或R b取代; R3是氢，卤素，氰基，烷基，卤代烷基，烷氧基，卤代烷氧基或烯氧基; R4是氢，卤素，氰基，羟基，巯基，叠氮基，烷基，烯基，炔基，卤代烷基，烷氧基，烯氧基，炔氧基，卤代烷氧基，烷硫基，烯硫基，炔硫基，卤代烷硫基，-ON-CRaRb，-CRc-NORa，-NRcN -CRaRb，-NRaRb，-NRcNRaRb，-NORa，-NRcC（-NRc'）NRaRb，-NRcC（-O）NRaRb，-NRaC（-O）Rc，-NRaC（-NORc）Rc'，-OC（ - O）R c，-C（-NOR c）NR a R b，-CR c（-NNR a R b）， - C（-O）NR a R b或-C（-O）R c; 其中Ra，Rb和Rc如说明书中所定义; X是卤素，烷基，烷氧基或卤代烷基; m为1〜5的整数。 描述了制备这些化合物的方法，包含它们的组合物及其用于控制​​有害真菌的用途。

公开(公告)号：US07763622B2

公开(公告)日：2010-07-27

申请号：US10532719

申请日：2003-11-04

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  A61K31/519 ,  C07D471/00 ,  C07D487/00 ,  C07D491/00

CPC分类号： C07C69/65 ,  A01N43/90 ,  C07D487/04

摘要： Substituted 6-(2-halogenphenyl)-triazolopyrimidines of formula I in which R1 denote alkyl, alkenyl, alkynyl, alkadienyl, haloalkyl, haloalkenyl, cycloalkyl, phenyl, naphthyl, or a 5- or 6-membered saturated, unsaturated, or aromatic heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, wherein R1 and R2 radicals may be substituted as defined in the description, R2 denote hydrogen, or a group mentioned for R1; or R1 and R2 together with the interjacent nitrogen atom represent a 5- or 6-membered heterocycle, containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, which ring may be substituted as defined in the description; Hal is halogen; L1, L3 independently denote hydrogen, halogen, or alkyl; L2 is hydrogen, halogen, haloalkyl, or NH2, NHRb, or N(Rb)2, wherein Rb is as defined in the description, wherein at least one from L1, L2, and L3 is not hydrogen; X is halogen, cyano, alkyl, alkoxy, haloalkoxy or alkenyloxy. processes for their preparation, compositions containing them and to their use for combating phytopathogenic fungi.

摘要翻译： 取代的式I的6-（2-卤代苯基） - 三唑并嘧啶，其中R 1表示烷基，烯基，炔基，链二烯基，卤代烷基，卤代烯基，环烷基，苯基，萘基或5-或6-元饱和，不饱和或芳族杂环 含有一至四个氮原子或一至三个氮原子和一个硫或氧原子，其中R 1和R 2基团可以如说明书中所定义而被取代，R 2表示氢或R 1所提及的基团; 或R1和R2与相邻的氮原子一起表示含有1-4个氮原子或一至三个氮原子和一个硫或氧原子的5-或6-元杂环，该环可以如说明书中所定义而被取代; 卤素是卤素; L 1，L 3独立地表示氢，卤素或烷基; L2是氢，卤素，卤代烷基或NH2，NHRb或N（Rb）2，其中Rb如说明书中所定义，其中L1，L2和L3中的至少一个不是氢; X是卤素，氰基，烷基，烷氧基，卤代烷氧基或烯氧基。 其制备方法，含有它们的组合物及其用于对抗植物病原真菌的用途。

公开(公告)号：US07709637B2

公开(公告)日：2010-05-04

申请号：US11548864

申请日：2006-10-12

申请人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D403/04 ,  C07D239/38

CPC分类号： C07D239/42 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/647 ,  A01N43/653 ,  A01N43/713 ,  A01N43/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04 ,  C07D473/06 ,  C07D487/04

摘要： 5-Phenylpyrimidines of the formula I, in which the substituents have the following meanings: R1 is a five- to ten-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle comprising one to four hetero atoms selected from the group consisting of O, N or S, which heterocycle can be substituted as defined in the description, R2 is hydrogen, halogen, cyano, alkyl, haloalkyl or alkoxy; R3, R4 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, R3 and R4 together with the nitrogen atom to which they are bonded may also form a five- or six-membered ring which can be interrupted by a hetero atom and have attached to it one or more substituents; R5, R6 are hydrogen, halogen, alkyl, haloalkyl or alkoxy; R7, R8 are hydrogen, halogen, alkyl or haloalkyl; R9 is hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, haloalkoxy or alkoxycarbonyl, Processes and intermediates for the preparation of these compounds, and their use for controlling harmful fungi.

摘要翻译： 式I的5-苯基嘧啶，其中取代基具有以下含义：R 1是5至10元饱和的，部分不饱和的或芳族的单环或双环杂环，其包含一至四个选自O ，N或S，该杂环可以如描述中所定义而被取代，R 2是氢，卤素，氰基，烷基，卤代烷基或烷氧基; R3，R4是氢，烷基，卤代烷基，环烷基，卤代环烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，R3和R4与它们所键合的氮原子一起也可以形成五元或六元环 其可以被杂原子中断并且与其连接一个或多个取代基; R5，R6是氢，卤素，烷基，卤代烷基或烷氧基; R 7，R 8为氢，卤素，烷基或卤代烷基; R9是氢，卤素，烷基，烷氧基，环烷氧基，卤代烷氧基或烷氧羰基。用于制备这些化合物的方法和中间体及其用于控制​​有害真菌的用途。

公开(公告)号：US07335661B2

公开(公告)日：2008-02-26

申请号：US10532770

申请日：2003-11-14

申请人： Jordi Tormo i Blasco ,  Thomas Grote ,  Eberhard Ammermann ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schöfl

发明人： Jordi Tormo i Blasco ,  Thomas Grote ,  Eberhard Ammermann ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schöfl

IPC分类号： A01N43/90 ,  A01N43/40

CPC分类号： A01N43/90 ,  A01N43/40 ,  A01N2300/00

摘要： Fungicidal mixtures, comprising A) the triazolopyrimidine of the formula I  and B) amide compounds of the formula II where X1 and X2 are halogen, nitro, cyano, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, alkoxy, haloalkoxy, haloalkylthio, alkylsulfinyl or alkylsulfonyl; x is 1, 2, 3 or 4; and y is 1, 2, 3, 4 or 5; in a synergistically effective amount, methods for controlling harmful fungi using mixtures of the compounds I and II, compositions comprising these compounds and the use of the compounds I and II for preparing such mixtures are described.

摘要翻译： 杀真菌混合物，其包含A）式I的三唑并嘧啶和B）式II的酰胺化合物，其中X 1和X 2是卤素，硝基，氰基，烷基， 烯基，炔基，卤代烷基，卤代烯基，卤代炔基，烷氧基，卤代烷氧基，卤代烷硫基，烷基亚磺酰基或烷基磺酰基; x为1,2,3或4; y为1,2,3,4或5; 在协同有效量下，描述了使用化合物I和II的混合物来控制有害真菌的方法，包含这些化合物的组合物以及化合物I和II用于制备这种混合物的用途。

公开(公告)号：US07320975B2

公开(公告)日：2008-01-22

申请号：US10505146

申请日：2003-02-06

申请人： Frank Schieweck ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Müller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwögler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Frank Schieweck ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Bernd Müller ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Wassilios Grammenos ,  Markus Gewehr ,  Anja Schwögler ,  Carsten Blettner ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D401/04 ,  A01N43/54

CPC分类号： C07D401/04

摘要： The invention relates to 2-(2-pyridyl)-5-phenyl-6-aminopyrimidines of formula I, wherein the substitutes and the index have the following meaning: R1 represents halogen, hydroxy, hyano, hxo, nitro, amino, mercapto, alkyl, halogenalkyl, alkenyl, alkinyl, cycloalkyl, alkoxy, halogenalkoxy, carboxyl, alkoxycarbonyl, carbamoyl, alkylaminocarbonyl, dialkylamincarbonyl, morpholinocarbonyl, pyrrolidinocarbonyl, alkylcarbonylamino, alkylamino. dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, hydroxysulfonyl, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl; m=0 or 1-4; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3, R4 represents hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, R3 and R4 together with the nitrogen atom to which they are connected, form a five or six-membered ring which is interrupted by an atom from the group O, N or S and/or can be substituted according to the description; R5 represents halogen, alkyl or halogenalkyl; R6 represents hydrogen or one of the known groups in R5; R7, R8 represent hydrogen, halogen, alkyl or halogenalkyl; R9 represents hydrogen, halogen, hydroxy, cyano, alkyl, alkoxy, cycloalkoxy, halogenalkoxy, alkoxycarbonyl or alkylaminocarbonyl. The invention also relates to a method and intermediate product for the production of said compound in addition to the use thereof for combating undesirable plants

摘要翻译： 本发明涉及式I的2-（2-吡啶基）-5-苯基-6-氨基嘧啶，其中取代基和指数具有以下含义：R 1表示卤素，羟基，杂环基， 烷氧基，烷氧基羰基，氨基甲酰基，烷基氨基羰基，二烷基氨基羰基，吗啉代羰基，吡咯烷基羰基，烷基羰基氨基，烷基氨基。 二烷基氨基，烷硫基，烷基亚磺酰基，烷基磺酰基，羟基磺酰基，氨基磺酰基，烷基氨基磺酰基，二烷基氨基磺酰基; m = 0或1-4; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3，R 4表示氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，R 3 O 和R 4与它们连接的氮原子一起形成5或6元环，其被来自基团O，N或S的原子和/或可被取代 根据说明; R 5表示卤素，烷基或卤代烷基; R 6表示氢或R 5中的已知基团之一; R 7，R 8表示氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，羟基，氰基，烷基，烷氧基，环烷氧基，卤代烷氧基，烷氧基羰基或烷基氨基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物，除了其用于对抗不期望的植物之外

公开(公告)号：US07153860B2

公开(公告)日：2006-12-26

申请号：US10471532

申请日：2002-03-13

申请人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： C07D239/42 ,  A01N43/54 ,  C07D239/47

CPC分类号： C07D239/42 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/647 ,  A01N43/653 ,  A01N43/713 ,  A01N43/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04 ,  C07D473/06 ,  C07D487/04

摘要： The invention relates to 5-phenylpyrimidine of formula (I) wherein the substituents have the following designations: R1 represents a five to ten-membered saturated, partially unsaturated or aromatic monocyclic or bicyclic heterocycle which contains between one and four heteroatoms from the group O, N or S, and which can be substituted as defined in the description; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3 and R4 represent hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl; together with the nitrogen atom to which they are bonded, R3 and R4 can also form a five or six-membered ring which can be split by a heteroatom and can carry at least one substituent; R5 and R6 represent hydrogen, halogen, alkyl, halogenalkyl or alkoxy; R1 and R8 represent hydrogen, halogen, alkyl or halogenalkyl; and R9 represents hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, halogenalkoxy or alkoxycarbonyl. The invention also relates to methods and intermediate products for producing said compounds and the use of the same for controlling pathogenic fungi

摘要翻译： 本发明涉及式（I）的5-苯基嘧啶，其中取代基具有以下指定：R 1表示5至10元饱和，部分不饱和或芳族单环或双环杂环，其含有一个 和来自O，N或S基团的四个杂原子，并且可以如说明书中定义的那样被取代; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3和R 4代表氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基; 与它们所键合的氮原子一起，R 3和R 4还可以形成五元或六元环，其可以被杂原子分解并且可以携带 至少一个取代基; R 5和R 6代表氢，卤素，烷基，卤代烷基或烷氧基; R 1和R 8代表氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，烷基，烷氧基，环烷氧基，卤代烷氧基或烷氧基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物及其用于控制​​致病真菌的用途