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11.
公开(公告)号:US20080089930A1
公开(公告)日:2008-04-17
申请号:US11945614
申请日:2007-11-27
CPC分类号: A61K8/042 , A61F2013/530481 , A61F2013/530613 , A61K8/65 , A61K9/0024 , A61K9/06 , A61K9/146 , A61K9/2063 , A61K9/7007 , A61K38/015 , A61K38/17 , A61K47/42 , A61K47/6953 , A61L15/32 , A61L15/60 , A61L27/227 , A61L27/52 , A61Q19/00
摘要: A hydratable, highly absorbent keratin solid fiber or powder capable of absorbing a large weight excess of water may be produced by partially oxidizing hair keratin disulfide bonds to sulfonic acid residues and reacting the sulfonic acid residues with a cation. The neutralized suspension can be filtered, washed, and dried, leaving keratin solid which can be shredded into fibers and further ground into powder. Addition of water to the solid produces a hydrogel. The powder or hydrogel may be useful as an absorbent material, as a therapeutic for skin, or as an excipient. The keratin materials can be incorporated into nonwoven films. The hydrogel can be used as a biocompatible viscoelastic filler for implant applications. Another use for the absorbent keratin and keratin hydrogel is as an excipient in pharmaceutical and cosmetic applications.
摘要翻译: 可以通过将毛发角蛋白二硫键部分氧化成磺酸残基并使磺酸残基与阳离子反应来制备能够吸收大量过量水的可水合的高吸收性角蛋白固体纤维或粉末。 中和的悬浮液可以过滤,洗涤和干燥,留下角蛋白固体,将其切成纤维并进一步研磨成粉末。 向固体中加入水产生水凝胶。 粉末或水凝胶可用作吸收材料,作为皮肤的治疗剂或赋形剂。 角蛋白材料可以并入无纺膜中。 水凝胶可用作植入物应用的生物相容性粘弹性填料。 吸收性角蛋白和角蛋白水凝胶的另一用途是作为药物和化妆品应用中的赋形剂。
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公开(公告)号:US07001988B2
公开(公告)日:2006-02-21
申请号:US10254364
申请日:2002-09-25
申请人: Mark Van Dyke
发明人: Mark Van Dyke
IPC分类号: C07K14/47
CPC分类号: C07K14/4741 , C07K1/1136 , C08H1/06 , C08L89/06
摘要: Methods for chemically modifying peptides, preferably keratinaceous feedstocks, to achieve desired solubility characteristics; stable solvent systems for preparing the modified peptides; and, the resulting chemically modified peptides.
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公开(公告)号:US06410144B2
公开(公告)日:2002-06-25
申请号:US09342542
申请日:1999-06-29
申请人: Geoffrey Dearnaley , Mark Van Dyke
发明人: Geoffrey Dearnaley , Mark Van Dyke
IPC分类号: B32B900
CPC分类号: C25D11/18 , Y10T428/249967 , Y10T428/24997 , Y10T428/249987 , Y10T428/24999 , Y10T428/30
摘要: An amorphous carbon film, preferably disposed on and substantially filling the pores in a porous anodized aluminum outer surface, wherein the amorphous carbon film comprises as an integral component an effective amount of a lubricity-increasing agent, preferably sulfur.
摘要翻译: 无定形碳膜优选地设置在多孔阳极氧化铝外表面上并基本上填充多孔阳极氧化铝外表面中的孔,其中无定形碳膜作为积分组分包含有效量的增润剂,优选硫。
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公开(公告)号:US10400019B2
公开(公告)日:2019-09-03
申请号:US15308285
申请日:2015-05-01
申请人: Mark Van Dyke , Maria Rahmany
发明人: Mark Van Dyke , Maria Rahmany
摘要: The present disclosure relates to keratin nanomaterials, methods for obtaining keratin nanomaterials, and biomaterials made from keratin nanomaterials. In particular, keratin nanomaterials comprising Type I and Type II monomer pairs are disclosed as well as a method for obtaining keratin nanomaterials comprising obtaining a solution of keratin and processing the solution by ultrafiltration with buffer solution containing phosphate.
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公开(公告)号:US20090148488A1
公开(公告)日:2009-06-11
申请号:US12390360
申请日:2009-02-20
CPC分类号: A61L27/34 , B60Q1/2661 , B60R2019/505 , C09D189/04 , C09D189/06 , C08L89/04 , C08L2666/28
摘要: A medical device (and method for making same) comprising a passivating coating comprising keratin.
摘要翻译: 包括包含角蛋白的钝化涂层的医疗装置(及其制造方法)。
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公开(公告)号:US20070166348A1
公开(公告)日:2007-07-19
申请号:US11549748
申请日:2006-10-16
申请人: Mark Van Dyke
发明人: Mark Van Dyke
IPC分类号: A61K38/18 , A61K31/715 , A61F2/02
CPC分类号: A61L27/54 , A61L27/425 , A61L27/58 , A61L2300/406 , A61L2430/02
摘要: A malleable bone graft composition is described. The composition comprises: (a) keratose; (b) particulate filler; (c) antibiotic; and (f) water. The invention may be provided in sterile form in an container, and optionally lyophilized. Methods of treating a fracture with such compositions are also described.
摘要翻译: 描述了可延展的骨移植组合物。 组合物包含:(a)角质旋转; (b)颗粒填料; (c)抗生素; 和(d)水。 本发明可以无菌形式提供在容器中,并且任选地冻干。 还描述了用这种组合物治疗骨折的方法。
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公开(公告)号:US06514565B2
公开(公告)日:2003-02-04
申请号:US09827562
申请日:2001-04-06
申请人: Geoffrey Dearnaley , Mark Van Dyke
发明人: Geoffrey Dearnaley , Mark Van Dyke
IPC分类号: C23C1626
CPC分类号: C25D11/18 , Y10T428/249967 , Y10T428/24997 , Y10T428/249987 , Y10T428/24999 , Y10T428/30
摘要: An amorphous carbon film, preferably disposed on and substantially filling the pores in a porous anodized aluminum outer surface, wherein the amorphous carbon film comprises as an integral component an effective amount of a lubricity-increasing agent, preferably sulfur.
摘要翻译: 无定形碳膜优选地设置在多孔阳极氧化铝外表面上并基本上填充多孔阳极氧化铝外表面中的孔,其中无定形碳膜作为积分组分包含有效量的增润剂,优选硫。
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公开(公告)号:USD343721S
公开(公告)日:1994-02-01
申请号:US878781
申请日:1992-05-05
申请人: Mark Van Dyke
设计人: Mark Van Dyke
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公开(公告)号:US4502328A
公开(公告)日:1985-03-05
申请号:US406874
申请日:1982-08-10
申请人: John F. Wood , Mark Van Dyke
发明人: John F. Wood , Mark Van Dyke
IPC分类号: G01M1/22
CPC分类号: G01M1/225
摘要: A dynamic electric wheel balancer for measuring the imbalance condition in a vehicle wheel and indicating the position and correction weights required for balancing the wheel in one or two planes. The wheel balancer contains a rotating shaft in order to make the dynamic measurements. The shaft is freewheeling during measurement and is brought up to a predetermined minimum r.p.m. value through a motor and clutch arrangement. In order to take the measurements, piezoelectric sensors are used to measure the vertical force components exhibited by the imbalance condition of the vehicle wheel secured to the rotating main shaft. The measured force components are converted into digital form. The balancer finds the definite integral of each of the forces generated by the piezoelectric transducers and uses the cross correlation data generated by these integrations to find the zero crossing points and the peak determinations. Also forming part of the wheel balancer is a device for compensating for velocity variation taking place during the freewheeling rotation of the main shaft. The compensated data is processed and displayed in an eye readable format to tell an operator where to place a weight and how much the weight should be in order to correct the imbalance condition in the wheel.
摘要翻译: 一种动态电动车轮平衡器,用于测量车辆车轮的不平衡状况,并指示在一个或两个平面中平衡车轮所需的位置和校正重量。 车轮平衡器包含旋转轴以进行动态测量。 轴在测量期间自由运转,并达到预定的最小r.p.m。 通过电机和离合器装置的值。 为了进行测量,使用压电传感器来测量由固定到旋转主轴的车轮的不平衡状态所显示的垂直力分量。 测量的力分量被转换为数字形式。 平衡器找到由压电传感器产生的每个力的确定积分,并使用由这些积分产生的互相关数据来找到过零点和峰值确定。 还形成车轮平衡器的一部分是用于补偿在主轴的续流旋转期间发生的速度变化的装置。 经补偿的数据以眼睛可读的格式进行处理和显示,以告诉操作员在哪里放置重量,以及为了校正车轮中的不平衡状况应该有多少重量。
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