摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
摘要:
An entity-based search system is described herein that detects and recognizes entities in Internet-based content and uses this recognition to organize search results. The system associates one or more entity identifiers with a web page and stores this information as metadata of the page in a search engine index. This metadata will enable entity-based queries as well as rich data presentations in a search engine result page (SERP), including grouping results by entities, filtering results by one or more particular entities, or re-ranking search results based on user preference of entities. Thus, the entity-based search system allows users to identify a particular entity the user is interested in finding, and to receive search results directly related to that entity.
摘要:
A method of recovering hydrocarbons from a porous subterranean hydrocarbon-bearing formation by: (a) reducing the salinity of a saline source water by reverse osmosis using a membrane having a first surface and a second surface by (i) feeding the saline source water to the first surface of the membrane, and (ii) removing treated water of reduced salinity from the second surface of the membrane; and (b) injecting the treated water into the formation; wherein the membrane is selectively permeable to water over dissolved solids such that when (i) the saline source water has a total dissolved solids content of at least 17,500 ppm, and (ii) the applied pressure across the membrane is greater than the osmotic pressure across the membrane and lies within the range 45 to 90 bar (4.5 to 9.0 M Pa), the total dissolved solids content of the treated water is in the range 500 to 5000 ppm.
摘要:
A current measurement system includes a magnetic core having an inside area through which a conductor carrying current to be measured extends. A measurement winding is wound on the magnetic core. A voltage source couples to the measurement winding to generate current through the measurement winding. A gap of low permeability material is disposed in the magnetic core. A sensing device is positioned in the gap, wherein the sensing device generates a control signal having one of a first state and a second state based on a strength and a direction of a magnetic field in the gap.
摘要:
A computer authentication device comprising a memory containing a long secret or digital signature, portions of which are requested by a server computer or other device. The authentication device evaluates the nature and timing of authentication requests and selectively varies the time delay for responding to such authentication requests. Such selective variation in response times impedes the unauthorized or malicious copying of the authentication device's authentication credentials.