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    Verifying Operator Competence
    12.
    发明申请
    Verifying Operator Competence 审中-公开
    验证操作员能力

    公开(公告)号：US20090299827A1

    公开(公告)日：2009-12-03

    申请号：US12130037

    申请日：2008-05-30

    Applicant: Srinivasulu Puri ,  Srikanth Karimisetty ,  Savita Durgada ,  Pawan Kumar ,  Susruth Doddapaneni

    Inventor： Srinivasulu Puri ,  Srikanth Karimisetty ,  Savita Durgada ,  Pawan Kumar ,  Susruth Doddapaneni

    IPC: G06Q10/00

    CPC classification number: G06Q10/10 ,  G06Q10/06398

    Abstract: Systems and methods are disclosed herein for verifying the competence of an operator in a manufacturing facility. In one implementation, for example, an operator competence verifying system comprises one or more input/output (“I/O”) devices configured to receive information from a user and provide information to the user. The system also comprises a processing device, which is configured to enable the user to set up a competence profile of an operator in the manufacturing facility. The processing device is further configured to enable the user to define jobs related to handling sensitive material at multiple material handling stages in the manufacturing facility. Also, the processing device is configured to assign training to the operator as needed to meet industry guidelines. The processing device is also configured to enable the user to define competence levels required at each multiple material handling stage.

    Abstract translation: 本文公开的系统和方法用于验证制造设施中的操作者的能力。 在一个实现中，例如，操作员能力验证系统包括被配置为从用户接收信息并向用户提供信息的一个或多个输入/输出（“I / O”）设备。 该系统还包括处理装置，其被配置为使得用户能够在制造设施中建立操作者的能力简档。 处理装置还被配置为使得用户能够在制造设施中的多个材料处理阶段定义与处理敏感材料相关的作业。 此外，处理装置被配置为根据需要向操作者分配训练以满足行业指导。 处理设备还被配置为使得用户能够定义在每个多个物料搬运阶段所需的能力等级。

    Surface-Modified Zeolite and Process for Synthesis Thereof for Sequestration of Anions
    13.
    发明申请
    Surface-Modified Zeolite and Process for Synthesis Thereof for Sequestration of Anions 有权
    表面改性沸石及其合成方法用于阴离子螯合

    公开(公告)号：US20070210006A1

    公开(公告)日：2007-09-13

    申请号：US11466636

    申请日：2006-08-23

    Applicant: Sadhana Suresh Rayalu ,  Pawan Kumar ,  Siddharth Ulhas Meshram ,  Amit Kumar Bansiwal ,  Nitin Kumar Labhsetwar ,  Rishi Narayan Singh ,  Sukumar Devotta

    Inventor： Sadhana Suresh Rayalu ,  Pawan Kumar ,  Siddharth Ulhas Meshram ,  Amit Kumar Bansiwal ,  Nitin Kumar Labhsetwar ,  Rishi Narayan Singh ,  Sukumar Devotta

    IPC: C02F1/42

    CPC classification number: B01J20/186 ,  C01B39/026 ,  C02F1/281 ,  C02F2101/103 ,  C02F2103/06

    Abstract: Present invention deals with cost-effective surface-modified zeolite materials developed from commercial zeolites and flyash-based zeolites by treating with surface modifiers like hexadecyltrimethyl ammonium bromide (HDTMA-Br). The formation of zeolitic materials with anionic characteristics requires treatment with a surfactant with initial concentrations greater than its critical micelle concentration (CMC). The sorption of oxyanions on the surfactant-modified zeolite (SMZ) is attributed to surface complexation and surface precipitation. Incorporation of metal ions on SMZ showed improved anion uptake for dearsenification of water due to synergistic effects and is able to meet the stringent target of 10 ppb of As on potable water being adopted by most countries. High selectivity, faster kinetics and high adsorption capacity ensures cost effectiveness of this product as compared to other low-cost products for dearsenification. Zeolite analogues with anionic characteristics have been developed for their applications for removal of arsenic from water. The material developed can also be used to remove other anions like chromium and selenium.

    Abstract translation: 本发明涉及通过用诸如十六烷基三甲基溴化铵（HDTMA-Br）的表面改性剂处理从商业沸石和飞灰基沸石开发的经济有效的表面改性沸石材料。 具有阴离子特性的沸石材料的形成需要用初始浓度大于其临界胶束浓度（CMC）的表面活性剂进行处理。 氧杂阴离子对表面活性剂改性沸石（SMZ）的吸附归因于表面络合和表面沉淀。 金属离子在SMZ上的结合表现出改善的阴离子吸收，由于协同作用而使水脱水，并且能够达到大部分国家所采用的10 ppb As对饮用水的严格目标。 与其他低成本脱砷产品相比，高选择性，更快的动力学和高吸附能力确保了该产品的成本效益。 已经开发了具有阴离子特性的沸石类似物用于从水中除去砷的应用。 开发的材料也可用于除去其他阴离子如铬和硒。

    SYSTEM AND METHOD FOR DAY-ZERO AUTHENTICATION OF ACTIVEX CONTROLS
    15.
    发明申请
    SYSTEM AND METHOD FOR DAY-ZERO AUTHENTICATION OF ACTIVEX CONTROLS 审中-公开
    用于ActiveX控件的零点认证的系统和方法

    公开(公告)号：US20130055369A1

    公开(公告)日：2013-02-28

    申请号：US13216388

    申请日：2011-08-24

    Applicant: Pawan Kumar ,  Rohit Gupta ,  Manoj Badola

    Inventor： Pawan Kumar ,  Rohit Gupta ,  Manoj Badola

    IPC: H04L9/32 ,  G06F15/16 ,  G06F21/00

    CPC classification number: G06F21/572 ,  G06F21/51 ,  G06F21/52 ,  H04L9/3247 ,  H04L63/0823 ,  H04W4/50

    Abstract: A system and method in one embodiment includes modules for verifying a digital signature of a Microsoft® ActiveX® control, identifying an executable file of the ActiveX control, authorizing the executable file as an updater configured to enable trust propagation, if the digital signature is from an authorized issuer, and installing the ActiveX control. More specific embodiments include hooking an exported function in the executable file and marking a thread calling the exported function as an updater. Hooking the exported function includes patching the executable function so that when the exported function is called during execution of the executable file, a second function is executed before the exported function is executed. Other embodiments include extracting a cabinet file wrapping the ActiveX control, parsing an information file in the cabinet file, and downloading additional components for installing the ActiveX control.

    Abstract translation: 一个实施例中的系统和方法包括用于验证Microsoft ActiveX控件的数字签名的模块，识别ActiveX控件的可执行文件，将可执行文件授权为配置为启用信任传播的更新器，如果数字签名来自 授权发行人，并安装ActiveX控件。 更具体的实施例包括将可导出的功能挂接在可执行文件中，并将一个线程称为导出的函数作为更新程序。 挂接导出的函数包括修补可执行函数，以便在执行可执行文件时调用导出函数时，在执行导出函数之前执行第二个函数。 其他实施例包括提取包装ActiveX控件的机柜文件，解析橱柜文件中的信息文件，以及下载用于安装ActiveX控件的附加组件。

    NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING NUCLEIC ACIDS
    17.
    发明申请
    NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING NUCLEIC ACIDS 有权
    用于靶向核酸的核酸功能化的一致的限制性核酸和寡核苷酸

    公开(公告)号：US20130337581A1

    公开(公告)日：2013-12-19

    申请号：US13922068

    申请日：2013-06-19

    Applicant: Patrick Jerzy Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    Inventor： Patrick Jerzy Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    IPC: C07H19/16 ,  C12Q1/68 ,  C07H19/10 ,  C07H19/06

    CPC classification number: C12Q1/6883 ,  C07H19/06 ,  C07H19/10 ,  C07H19/16

    Abstract: Embodiments are disclosed herein that involve C5-functionalized nucleic acids, which can be used for detecting a target in a nucleic acid. Particular embodiments disclose methods for making these compounds, wherein the compounds can be formed by coupling of an intermediate with a linker. Certain embodiments disclose the use of these compounds for detecting single nucleotide polymorphisms, and for increasing the thermal affinity of nucleic acid complements as compared to unmodified nucleic acid complements. In addition, the disclosed compounds can decrease enzymatic degradation of nucleic acids.

    Abstract translation: 本文公开的实施方案涉及可用于检测核酸中靶标的C5官能化核酸。 具体实施方案公开了制备这些化合物的方法，其中可以通过中间体与连接体的偶联形成化合物。 某些实施方案公开了这些化合物用于检测单核苷酸多态性的用途，并且与未修饰的核酸补体相比增加了核酸补充物的热亲和力。 此外，所公开的化合物可以降低核酸的酶降解。

    Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting of nucleic acids
    18.
    发明授权
    Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting of nucleic acids 有权
    用于靶向核酸的核碱基官能化构象限制性核苷酸和寡核苷酸

    公开(公告)号：US08518908B2

    公开(公告)日：2013-08-27

    申请号：US13416906

    申请日：2012-03-09

    Applicant: Patrick J. Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    Inventor： Patrick J. Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    IPC: A01N43/04 ,  A61K31/70

    CPC classification number: C12Q1/6883 ,  C07H19/06 ,  C07H19/10 ,  C07H19/16

    Abstract: Embodiments are disclosed herein that involve C5-functionalized nucleic acids, which can be used for detecting a target in a nucleic acid. Particular embodiments disclose methods for making these compounds, wherein the compounds can be formed by coupling of an intermediate with a linker. Certain embodiments disclose the use of these compounds for detecting single nucleotide polymorphisms, and for increasing the thermal affinity of nucleic acid complements as compared to unmodified nucleic acid complements. In addition, the disclosed compounds can decrease enzymatic degradation of nucleic acids.

    Abstract translation: 本文公开的实施方案涉及可用于检测核酸中靶标的C5官能化核酸。 具体实施方案公开了制备这些化合物的方法，其中可以通过中间体与连接体的偶联形成化合物。 某些实施方案公开了这些化合物用于检测单核苷酸多态性的用途，并且与未修饰的核酸补体相比增加了核酸补充物的热亲和力。 此外，所公开的化合物可以降低核酸的酶降解。

    NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING OF NUCLEIC ACIDS
    19.
    发明申请
    NUCLEOBASE-FUNCTIONALIZED CONFORMATIONALLY RESTRICTED NUCLEOTIDES AND OLIGONUCLEOTIDES FOR TARGETING OF NUCLEIC ACIDS 有权
    用于靶向核酸的核酸功能化的限制性核酸和寡核苷酸

    公开(公告)号：US20120295862A1

    公开(公告)日：2012-11-22

    申请号：US13416906

    申请日：2012-03-09

    Applicant: Patrick J. Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    Inventor： Patrick J. Hrdlicka ,  Pawan Kumar ,  Michael E. Østergaard

    IPC: A61K31/7072 ,  C07H19/06 ,  C07H19/10 ,  C07H19/16 ,  C12Q1/68 ,  A61K31/708

    CPC classification number: C12Q1/6883 ,  C07H19/06 ,  C07H19/10 ,  C07H19/16

    Abstract: Embodiments are disclosed herein that involve C5-functionalized nucleic acids, which can be used for detecting a target in a nucleic acid. Particular embodiments disclose methods for making these compounds, wherein the compounds can be formed by coupling of an intermediate with a linker. Certain embodiments disclose the use of these compounds for detecting single nucleotide polymorphisms, and for increasing the thermal affinity of nucleic acid complements as compared to unmodified nucleic acid complements. In addition, the disclosed compounds can decrease enzymatic degradation of nucleic acids.

    Abstract translation: 本文公开的实施方案涉及可用于检测核酸中靶标的C5官能化核酸。 具体实施方案公开了制备这些化合物的方法，其中可以通过中间体与连接体的偶联形成化合物。 某些实施方案公开了这些化合物用于检测单核苷酸多态性的用途，并且与未修饰的核酸补体相比增加了核酸补充物的热亲和力。 此外，所公开的化合物可以降低核酸的酶降解。

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