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    Compounds in the family of N-acylamino-amides, compositions comprising them, and uses
    11.
    发明授权
    Compounds in the family of N-acylamino-amides, compositions comprising them, and uses 有权

    公开(公告)号：US10098827B2

    公开(公告)日：2018-10-16

    申请号：US15536362

    申请日：2015-12-15

    Applicant: L'OREAL

    Inventor： Maria Dalko

    IPC: A61K38/00 ,  A61K8/44 ,  A61K8/64 ,  C07K5/062 ,  A61Q19/08

    Abstract: The present application relates to new compounds in the family of N-acylamino-amides having formula (I), compositions, in particular cosmetic compositions comprising them, and their use to treat the signs of aging of skin of the body or face, whether chronobiological or photo-induced, and in particular aging generated by reduced skin elasticity. in which p=1, 2 or 3 R independently denotes a cyano (—CN), hydroxy (—OH), CO2R′ group in which R′ denotes a hydrogen atom or linear or branched C1-C6 alkyl group, R1 denotes a hydrogen atom or a linear or branched C1-C6 alkyl group, and also the salts and/or isomers and/or solvates thereof.

    Use of vanillin derivatives as a preservative, preservation method, compounds, and composition
    14.
    发明授权
    Use of vanillin derivatives as a preservative, preservation method, compounds, and composition 有权

    公开(公告)号：US11306051B2

    公开(公告)日：2022-04-19

    申请号：US16894258

    申请日：2020-06-05

    Applicant: L'OREAL

    Inventor： Maria Dalko

    IPC: A61K8/35 ,  A61Q19/00 ,  C07C49/255 ,  A61K47/10

    Abstract: The present invention relates to the use, in a cosmetic, dermatological or pharmaceutical composition, of at least one compound of formula (I): in which: R2 represents a hydrogen atom or a methyl or ethyl radical; R3 represents a linear C1-C12 alkyl radical, optionally substituted with a hydroxyl group; or a linear C2-C12 alkenyl radical, optionally substituted with a hydroxyl group; as a preserving agent. The invention also relates to certain novel compounds and to the cosmetic, dermatological or pharmaceutical compositions comprising them.

    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss
    20.
    发明授权
    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss 有权
    施用吡啶二羧酸化合物用于刺激或诱导人角质纤维的生长和/或阻止其损失

    公开(公告)号：US09107847B2

    公开(公告)日：2015-08-18

    申请号：US13662592

    申请日：2012-10-29

    Applicant: Societe L'Oreal S.A.

    Inventor： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC: A61K8/49 ,  A61Q7/00 ,  A61Q1/10 ,  A61K8/37

    CPC classification number: A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    Abstract: The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    Abstract translation: 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和和直链或支链的C 1 -C 18烷基或芳基， 任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代的烷基或芳基，或R'和R“一起表示杂环，该组合物旨在诱导和/或刺激人角质纤维的生长， 如头发和睫毛，和/或减慢他们的损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

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