Carrier system for water-soluble active ingredients
    13.
    发明授权
    Carrier system for water-soluble active ingredients 有权
    载体系统为水溶性活性成分

    公开(公告)号:US09237998B2

    公开(公告)日:2016-01-19

    申请号:US14136634

    申请日:2013-12-20

    Applicant: L'OREAL

    Abstract: A water releasing composition in the form of an emulsion and process for using the composition are provided. The composition includes an aqueous phase and an oil phase. The aqueous phase includes at least one water-soluble active ingredient at a concentration by weight of from about 0.1% to about 20%, based upon weight of the composition. The oil phase includes dimethicone at a concentration by weight of about 1% to about 25%, and an emulsifying crosslinked siloxane elastomer at a concentration by weight of about 0.1% to about 20%, both based upon weight of the composition. The composition has a phase ratio of the aqueous phase to the oil phase of about 3.0 to about 12.0. The composition converts from an emulsion to a plurality of droplets upon application of shear.

    Abstract translation: 提供乳液形式的释水组合物和使用该组合物的方法。 该组合物包括水相和油相。 水相包含至少一种水溶性活性成分,其浓度为组合物重量的约0.1%至约20%。 油相包括浓度为约1%至约25%的聚二甲基硅氧烷和基于组合物重量的浓度为约0.1%至约20%的乳化交联硅氧烷弹性体。 该组合物的水相与油相的相比为约3.0至约12.0。 当施加剪切时,组合物从乳液转化为多个液滴。

    TETRAPEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT
    14.
    发明申请
    TETRAPEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT 有权
    抗坏血酸和使用抗氧化剂的方法

    公开(公告)号:US20150374606A1

    公开(公告)日:2015-12-31

    申请号:US14315585

    申请日:2014-06-26

    Applicant: L'OREAL

    Abstract: A tetrapeptide having antioxidant activity is provided. The tetrapeptide has a structure comprising, in amino acid sequence from N-terminus to C-terminus: tryptophan-X-tyrosine-X; wherein X is arginine, lysine, histidine or any positively-charged amino acid derivative such as 5-hydroxylysine, ornithine, 2,4-diamino-butyrate and 2,3-diamino-propionate. Each amino acid of the sequence or its Homo-amino acid derivative is independently of the D configuration (D-stereoisomer) or of the L configuration (L-stereoisomer), and the C-terminal comprises one selected from the group consisting of carboxyl (—COOH), and carboxamide (—CONH2). A composition stabilized to oxidation or having antioxidant activity and a method for attenuating effects of free radicals on a keratinous material are also provided.

    Abstract translation: 提供了具有抗氧化活性的四肽。 四肽具有在N-末端至C末端的氨基酸序列中含有色氨酸-X-酪氨酸-X的结构; 其中X是精氨酸,赖氨酸,组氨酸或任何带正电荷的氨基酸衍生物如5-羟赖氨酸,鸟氨酸,2,4-二氨基丁酸酯和2,3-二氨基丙酸酯。 序列的每个氨基酸或其均聚氨基酸衍生物独立于D构型(D-立体异构体)或L构型(L-立体异构体),并且C-末端包括选自羧基( -COOH)和羧酰胺(-CONH 2)。 还提供稳定化为氧化或具有抗氧化活性的组合物以及减少自由基对角质材料的影响的方法。

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