METHOD OF PRODUCING PERSONALIZED BIOMIMETIC DRUG-ELUTING CORONARY STENTS BY 3D-PRINTING
    13.
    发明申请
    METHOD OF PRODUCING PERSONALIZED BIOMIMETIC DRUG-ELUTING CORONARY STENTS BY 3D-PRINTING 审中-公开
    通过3D打印生产个性化生物化学药物治疗冠状动脉瘤的方法

    公开(公告)号:US20160256610A1

    公开(公告)日:2016-09-08

    申请号:US14743782

    申请日:2015-06-18

    摘要: A method for using 3D printing technology produces personalized biomimetic drug-eluting coronary stent and the product thereof. The process of manufacturing stent, based on coronary angiography imaging data, measures the diameter of diseased coronary and conducts 3D reconstruction. A personalized stent for each patient according to diameter, length, and morphological characteristics of target vessel that suited to the lesion is produced. The coronary stent is formed from biodegradable poly-L-lactic acid (PLLA) or other materials. The stent is modeled by 3D printing and then coated with polymers carrying antiproliferative drug to reduce restenosis (the polymers is a mixture of antiproliferative drug and PDLLA at a ratio of 1:1). The biomimetic drug-eluting coronary stent produced by 3D printing technology is personalized stent for each patient according to different characteristics of diseased coronary, reduces the incidence of vascular injury, thrombosis, dissection and other complications caused by stent and vessel diameter mismatch.

    摘要翻译: 使用3D打印技术的方法产生个性化仿生药物洗脱冠状动脉支架及其产品。 制造支架的过程,基于冠状动脉造影成像数据,测量患病冠状动脉的直径并进行3D重建。 根据直径,长度和适合于病变的靶容器的形态特征,每个患者的个性化支架被产生。 冠状动脉支架由可生物降解的聚-L-乳酸(PLLA)或其他材料形成。 支架通过3D印刷进行建模,然后涂覆含有抗增殖药物的聚合物以减少再狭窄(聚合物是抗增殖药物和PDLLA的混合物,比例为1:1)。 通过3D打印技术生产的仿生药物洗脱冠状动脉支架根据患病冠状动脉的不同特点对个体化支架进行个性化支架,减少支架和血管直径不匹配引起的血管损伤,血栓形成,解剖等并发症的发生。

    PARALLEL PYRAMID ENTROPY CODING FOR VIDEO AND IMAGE COMPRESSION
    14.
    发明申请
    PARALLEL PYRAMID ENTROPY CODING FOR VIDEO AND IMAGE COMPRESSION 有权
    用于视频和图像压缩的并行PYRAMID熵编码

    公开(公告)号:US20130223536A1

    公开(公告)日:2013-08-29

    申请号:US13408404

    申请日:2012-02-29

    申请人: Lei ZHANG

    发明人: Lei ZHANG

    IPC分类号: H04N7/26

    CPC分类号: H04N19/91 H04N19/13

    摘要: Methods, systems, and computer program products are provided to divide code blocks, such as blocks of quantized coefficient of image or video data, into smaller blocks and sub-blocks that can be processed in parallel using layered entropy coding and decoding scheme. This division is accomplished while still encoding the entire code block using the same layered entropy coding scheme.

    摘要翻译: 提供了方法,系统和计算机程序产品,以将代码块(例如量化的图像或视频数据块)分割成可以使用分层熵编码和解码方案并行处理的较小块和子块。 在使用相同的分层熵编码方案仍然对整个码块进行编码的同时完成该划分。

    ADAPTING TRANSFORM COEFFICIENT SCALING IN VIDEO/IMAGE CODING TO BLOCK FEATURES IDENTIFIED IN THE TRANSFORM DOMAIN
    15.
    发明申请
    ADAPTING TRANSFORM COEFFICIENT SCALING IN VIDEO/IMAGE CODING TO BLOCK FEATURES IDENTIFIED IN THE TRANSFORM DOMAIN 审中-公开
    在视频/图像编码中适应变换系数缩放到变形域中识别的块特征

    公开(公告)号:US20130170555A1

    公开(公告)日:2013-07-04

    申请号:US13338877

    申请日:2011-12-28

    申请人: Lei ZHANG

    发明人: Lei ZHANG

    IPC分类号: H04N7/30

    摘要: Methods, systems, and computer program products are provided to provide transform coefficient scaling at a block level in both a video/image encoder and a video/image decoder, rather than at a sequence- or picture-level in existing coding techniques. When providing and communicating transform coefficient scaling at the block level, scaling matrices that adapt to block contents can be used to improve the visual acuity of a given block when encoding a video picture or still image, instead of having to select a scaling matrix that would be applied to the entire picture. This approach allows more detail to be preserved in video and image coding.

    摘要翻译: 提供方法,系统和计算机程序产品以在视频/图像编码器和视频/图像解码器中的块级提供变换系数缩放,而不是在现有编码技术中的序列或图片级。 当在块级提供和传送变换系数缩放时,可以使用适应块内容的缩放矩阵来改进对编码视频图像或静止图像时的给定块的视敏度,而不必选择缩放矩阵, 适用于整个图片。 这种方法允许在视频和图像编码中保留更多的细节。

    SYSTEMS AND METHODS FOR SELECTIVELY MIGRATING CELLS USING ELECTRIC FIELDS
    17.
    发明申请
    SYSTEMS AND METHODS FOR SELECTIVELY MIGRATING CELLS USING ELECTRIC FIELDS 有权
    使用电场选择性移动细胞的系统和方法

    公开(公告)号:US20140277273A1

    公开(公告)日:2014-09-18

    申请号:US13831655

    申请日:2013-03-15

    IPC分类号: A61N1/36

    摘要: Systems and methods are provided for migrating cells implanted or endogenous in tissue. The system may include first and second delivery electrodes configured for insertion in tissue and a direct current (DC) power source operatively coupled to the first and second delivery electrodes. The system further may include a programmable controller operatively coupled to the DC power source, wherein the programmable controller is programmed to direct the DC power source to deliver an electric field between the first delivery electrode and the second delivery electrode at a stimulation to nonstimulation ratio sufficient to cause the cells to migrate within tissue selectively.

    摘要翻译: 提供系统和方法用于迁移组织中植入或内源性的细胞。 该系统可以包括构造成用于插入组织的第一和第二输送电极以及可操作地耦合到第一和第二输送电极的直流(DC)电源。 系统还可以包括可操作地耦合到DC电源的可编程控制器,其中可编程控制器被编程为引导DC电源在第一输送电极和第二输送电极之间传递电场,以刺激足够的非刺激比 以使细胞选择性地在组织内迁移。

    THIAZOLE SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
    19.
    发明申请
    THIAZOLE SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS 审中-公开
    用于治疗神经损伤性疾病的噻唑磺酰胺化合物

    公开(公告)号:US20080108675A1

    公开(公告)日:2008-05-08

    申请号:US11935215

    申请日:2007-11-05

    申请人: Lei ZHANG

    发明人: Lei ZHANG

    摘要: The present invention relates to compounds of the Formula: wherein R1 to R6, X, Z and A are as defined. These compounds have activity inhibiting production of Aβ-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the present Formula.

    摘要翻译: 本发明涉及下式的化合物:其中R 1至R 6,X,Z和A如上所定义。 这些化合物具有抑制Abeta肽生产的活性。 本发明还涉及用于治疗疾病的药物组合物和方法,所述疾病例如包含本发明化合物的哺乳动物的神经变性疾病,例如阿尔茨海默氏病。

    ANNOTATION ADDITION METHOD, ANNOTATION ADDITION SYSTEM USING THE SAME, AND MACHINE-READABLE MEDIUM
    20.
    发明申请
    ANNOTATION ADDITION METHOD, ANNOTATION ADDITION SYSTEM USING THE SAME, AND MACHINE-READABLE MEDIUM 有权
    辅助添加方法,使用相同的补充添加系统和机器可读介质

    公开(公告)号:US20110229017A1

    公开(公告)日:2011-09-22

    申请号:US13005062

    申请日:2011-01-12

    IPC分类号: G06K9/62 G06K9/46 G06K9/00

    CPC分类号: G06F17/30038 G06F17/30256

    摘要: Disclosed are a method and a system for adding annotations into an input medium file. The method comprises a step of creating annotation detection models based on training samples formed by existing media files having annotations; a step of extracting coexistence coefficients of any two annotations based on appearance frequencies of the annotations in the training samples; a step of inputting the input medium file; a step of extracting sense-of-vision features from the input medium file; a step of obtaining initial annotations of the input medium file; a step of acquiring candidate annotations based on the initial annotations and the coexistence coefficients of the annotations in the training samples; and a step of selecting a final annotation set from the candidate annotations based on the sense-of-vision features of the input medium file and the coexistence coefficients by using the annotation detection models.

    摘要翻译: 公开了一种用于将注释添加到输入介质文件中的方法和系统。 该方法包括基于由具有注释的现有媒体文件形成的训练样本来创建注释检测模型的步骤; 基于训练样本中注释的出现频率,提取任意两个注释的共存系数的步骤; 输入输入媒体文件的步骤; 从输入介质文件中提取感觉视觉特征的步骤; 获取输入媒体文件的初始注释的步骤; 基于训练样本中注释的初始注释和共存系数获取候选注释的步骤; 以及通过使用注释检测模型,基于输入介质文件的视觉特征和共存系数从候选注释中选择最终注释集的步骤。