公开(公告)号：US08428739B2

公开(公告)日：2013-04-23

申请号：US12548275

申请日：2009-08-26

申请人： Ashish Ahuja ,  Avraham Caspi ,  Jessy Dorn ,  Robert J. Greenberg ,  Kelly H. McClure ,  Matthew J. McMahon ,  Devyani Nanduri

发明人： Ashish Ahuja ,  Avraham Caspi ,  Jessy Dorn ,  Robert J. Greenberg ,  Kelly H. McClure ,  Matthew J. McMahon ,  Devyani Nanduri

IPC分类号： A61N1/18

CPC分类号： A61N1/36046 ,  A61N1/37247

摘要： This system gives the experimenter great flexibility to present spatio-temporal stimulation patterns to a subject. A video configuration file (VCF) editor allows the experimenter to determine the electrical stimulation parameters for each electrode. A Pattern Stimulation software program allows direct stimulation of chosen patterns of electrodes, scaled by the subject's VCF, through a Graphical User Interface. The subject then responds by drawing the outline of the phosphene he or she perceives on a touchscreen. The Pattern Stimulation program saves all of the trial parameters and the parameters of an ellipse fit to their drawing, as well as a raw data file containing the input to the touchscreen is saved. After the experiment, offline image analysis can be performed to obtain a detailed quantitative description of the subject's percepts. Image descriptors can assigned to the touchscreen data; these image descriptors can be used to make formalized comparisons between various experimental conditions. Various types of image descriptors can be used, including simple ellipse fitting, projections of the 2-D drawings onto one-dimensional axes, calculations of Hu moments, PCA, and ICA.

摘要翻译： 该系统给予实验者极大的灵活性，以向受试者呈现时空刺激模式。 视频配置文件（VCF）编辑器允许实验者确定每个电极的电刺激参数。 图案刺激软件程序允许通过图形用户界面直接刺激由对象的VCF缩放的所选择的电极图案。 然后，该主题通过绘制他或她在触摸屏上感知的磷光体的轮廓来进行响应。 模式刺激程序将所有试验参数和椭圆参数保存到其图形中，并保存包含触摸屏输入的原始数据文件。 实验后，可以进行离线图像分析，以获得对主体感知的详细定量描述。 图像描述符可以分配给触摸屏数据; 这些图像描述符可用于在各种实验条件之间进行正式比较。 可以使用各种图像描述符，包括简单的椭圆拟合，将二维图纸投影到一维轴上，计算Hu矩，PCA和ICA。

公开(公告)号：US20120123501A1

公开(公告)日：2012-05-17

申请号：US13295931

申请日：2011-11-14

申请人： Robert J. Greenberg ,  Ashish Ahuja

发明人： Robert J. Greenberg ,  Ashish Ahuja

IPC分类号： A61F9/08 ,  A61N1/36

CPC分类号： A61N1/0543 ,  A61N1/36046

摘要： The present invention is an improved method of electrically stimulating percepts in a patient with a visual prosthesis, to induce a more controlled perception of light. In particular, the present invention is an improved electrode array to maximize retinal response. The array of the present invention is an array with a center section with no electrode, surrounded by a ring of small high density electrodes. Electrodes beyond to ring are gradually larger and more widely spaced.

摘要翻译： 本发明是一种用视觉假体电刺激患者感知的改进方法，以诱导对光的更受控制的感知。 特别地，本发明是一种改进的电极阵列，以使视网膜反应最大化。 本发明的阵列是具有没有电极的中心部分的阵列，被小的高密度电极的环包围。 超越环的电极逐渐变大并且间隔更广。

公开(公告)号：US06408118B1

公开(公告)日：2002-06-18

申请号：US09648948

申请日：2000-08-25

申请人： Ashish Ahuja ,  Benjamin John Eggleton ,  Jon W. Engelberth ,  Arturo Hale ,  Glen Robert Kowach ,  Sharad Ramanathan ,  Steven Herbert Simon ,  Paul Stephen Westbrook

发明人： Ashish Ahuja ,  Benjamin John Eggleton ,  Jon W. Engelberth ,  Arturo Hale ,  Glen Robert Kowach ,  Sharad Ramanathan ,  Steven Herbert Simon ,  Paul Stephen Westbrook

IPC分类号： G02B634

CPC分类号： G02B6/021 ,  G02B6/02 ,  G02B6/0229 ,  G02B6/124 ,  G02B6/138 ,  G02B6/14 ,  G02B6/245 ,  G02B6/2932 ,  G02B6/29322 ,  G02B6/29394 ,  G02B2006/12107

摘要： In accordance with the invention, an optical waveguide comprising a longitudinally extending core housing an optical grating and a cladding layer peripherally surrounding the core, is provided with an outer surface of the cladding layer having one or more perturbations. Each perturbation has a height with respect to the core that varies by at least 0.1 times a Bragg wavelength of the grating over the surface of the perturbation and covers an extent of the outer surface whose linear dimensions are less than 1 cm. The perturbations suppress cladding mode spectra and reduce short wavelength cladding mode loss.

摘要翻译： 根据本发明，包括容纳光栅的纵向延伸的芯和围绕芯的外围包层的光波导设置有包层的外表面，其具有一个或多个扰动。 每个扰动具有相对于芯的高度，其在扰动表面上变化至少0.1倍的光栅的布拉格波长，并且覆盖其线性尺寸小于1cm的外表面的程度。 扰动抑制包层模式光谱并减少短波长包层模式损耗。

公开(公告)号：US06427040B1

公开(公告)日：2002-07-30

申请号：US09533412

申请日：2000-03-22

申请人： Ashish Ahuja ,  Benjamin John Eggleton ,  Torben N. Nielson ,  John A. Rogers

发明人： Ashish Ahuja ,  Benjamin John Eggleton ,  Torben N. Nielson ,  John A. Rogers

IPC分类号： G02B634

CPC分类号： H01S3/06758 ,  G02B6/02104 ,  G02B6/02123 ,  G02B6/0218 ,  G02B6/02204 ,  G02B6/2932 ,  G02B6/29322 ,  G02B6/29395 ,  G02F1/0115 ,  G02F1/0147 ,  G02F2201/307 ,  H01S2301/04 ,  H04B10/2941

摘要： In accordance with the invention, an optical waveguide grating with an adjustable optical spacing profile comprises a waveguide grating in thermal contact with one or more resistive film coatings. A coating extends along the length of the grating and its local resistance varies along the length of the grating. In one embodiment, a plurality of overlaping coatings are chosen so the resistance variation of each is different, thereby permitting a variety of heat generation profiles to be effected by independent control of the coatings. The different heat generation profiles, in turn, proportionately change the grating geometric spacing and local refractive index along the grating length, providing the desired adjustable optical spacing profile. Other embodiments use resistive films with abruptly changing or periodically changing heating variation.

摘要翻译： 根据本发明，具有可调光学间隔分布的光波导光栅包括与一个或多个电阻膜涂层热接触的波导光栅。 涂层沿着光栅的长度延伸，其局部电阻沿光栅的长度变化。 在一个实施例中，选择多个重叠涂层，使得每个涂层的电阻变化是不同的，从而允许通过独立控制涂层来实现各种发热曲线。 不同的发热曲线反过来又沿着光栅长度成比例地改变光栅几何间距和局部折射率，从而提供所需的可调光学间距分布。 其他实施例使用具有突然变化或周期性变化的加热变化的电阻膜。