利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

54 条记录 (耗时 0.052 秒)

    Nicotine Immunonanotherapeutics
    15.
    发明申请
    Nicotine Immunonanotherapeutics 有权
    尼古丁免疫治疗

    公开(公告)号：US20100092425A1

    公开(公告)日：2010-04-15

    申请号：US12428388

    申请日：2009-04-22

    申请人： Ulrich von Andrian ,  Omid Farokhzad ,  Frank Alexis ,  Matteo Iannacone ,  Pamela Basto ,  Jinjun Shi ,  Ashley Moseman ,  Robert Langer

    发明人： Ulrich von Andrian ,  Omid Farokhzad ,  Frank Alexis ,  Matteo Iannacone ,  Pamela Basto ,  Jinjun Shi ,  Ashley Moseman ,  Robert Langer

    IPC分类号： A61K31/465 ,  A61K38/20 ,  A61K38/21 ,  A61P25/00

    CPC分类号： A61K39/00

    摘要： The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.

    摘要翻译： 本发明提供用于将纳米载体递送至免疫系统细胞的组合物和系统。 本发明提供能够刺激T细胞和/或B细胞中的免疫应答的纳米载体。 本发明提供包含具有多个尼古丁部分的免疫表面的纳米载体。 本发明提供包含本发明纳米载体的药物组合物。 本发明提供了设计，制造和使用本发明的纳米载体及其药物组合物的方法。 例如，本发明能够引发免疫应答的纳米载体和抗尼古丁抗体的产生。

    Graphite or carbon particulates for the lithium ion battery anode
    19.
    发明授权
    Graphite or carbon particulates for the lithium ion battery anode 有权
    用于锂离子电池阳极的石墨或碳颗粒

    公开(公告)号：US09437344B2

    公开(公告)日：2016-09-06

    申请号：US12804413

    申请日：2010-07-22

    申请人： Aruna Zhamu ,  Jinjun Shi ,  Guorong Chen ,  Qing Fang ,  Bor Z. Jang ,  Ming C. Wang

    发明人： Aruna Zhamu ,  Jinjun Shi ,  Guorong Chen ,  Qing Fang ,  Bor Z. Jang ,  Ming C. Wang

    IPC分类号： B32B9/00 ,  H01B1/12 ,  C01B31/04 ,  H01M4/133 ,  H01M4/587 ,  H01M10/0525

    CPC分类号： H01B1/122 ,  C01B32/20 ,  H01M4/133 ,  H01M4/587 ,  H01M10/0525 ,  Y02T10/7011 ,  Y10T428/30

    摘要： This invention provides a graphite or graphite-carbon particulate for use as a lithium secondary battery anode material having a high-rate capability. The particulate is formed of a core carbon or graphite particle and a plurality of satellite carbon or graphite particles that are each separately bonded to the core particle wherein the core particle is spherical in shape, slightly elongate in shape with a major axis-to-minor axis ratio less than 2, or fibril in shape, and wherein the satellite particles are disc-, platelet-, or flake-like particles each containing a graphite crystallite with a crystallographic c-axis dimension Lc and a lateral dimension. Preferably, Lc is less than 100 nm and the flake/platelet lateral dimension is less than 1 μm. The core particle may be selected from natural graphite, artificial graphite, spherical graphite, graphitic coke, meso-carbon micro-bead, soft carbon, hard carbon, graphitic fibril, carbon nano-fiber, carbon fiber, or graphite fiber. Preferably, the flat-shaped particles are randomly oriented with respect to one another.

    摘要翻译： 本发明提供一种用作具有高速率能力的锂二次电池负极材料的石墨或石墨 - 碳颗粒。 颗粒由芯碳或石墨颗粒和多个卫星碳或石墨颗粒形成，每个卫星碳或石墨颗粒分别与核心颗粒结合，其中核心颗粒是球形的，具有略长的形状，具有长轴对次要的 轴比小于2，或原纤维形状，并且其中卫星颗粒是盘状，片状或片状颗粒，每个颗粒含有具有晶体c轴尺寸Lc和横向尺寸的石墨微晶。 优选地，Lc小于100nm，片/横板尺寸小于1μm。 核心颗粒可以选自天然石墨，人造石墨，球形石墨，石墨焦炭，内消旋碳微珠，软碳，硬碳，石墨原纤，碳纳米纤维，碳纤维或石墨纤维。 优选地，扁平形颗粒相对于彼此是随机取向的。

    Graphene nanocomposites for electrochemical cell electrodes
    20.
    发明授权
    Graphene nanocomposites for electrochemical cell electrodes 有权
    用于电化学电池电极的石墨烯纳米复合材料

    公开(公告)号：US09190667B2

    公开(公告)日：2015-11-17

    申请号：US12220651

    申请日：2008-07-28

    申请人： Aruna Zhamu ,  Bor Z. Jang ,  Jinjun Shi

    发明人： Aruna Zhamu ,  Bor Z. Jang ,  Jinjun Shi

    IPC分类号： H01M4/13 ,  H01M4/587 ,  H01G9/04 ,  H01G11/36 ,  H01G11/38 ,  H01G11/42 ,  H01M4/133 ,  H01M4/1393 ,  H01M4/36 ,  H01M4/62 ,  H01M10/0525 ,  H01M4/02

    CPC分类号： H01M4/587 ,  H01G9/058 ,  H01G11/36 ,  H01G11/38 ,  H01G11/42 ,  H01M4/133 ,  H01M4/1393 ,  H01M4/362 ,  H01M4/621 ,  H01M10/0525 ,  H01M2004/021 ,  H01M2004/022 ,  Y02E60/122 ,  Y02E60/13

    摘要： A composite composition for electrochemical cell electrode applications, the composition comprising multiple solid particles, wherein (a) a solid particle is composed of graphene platelets dispersed in or bonded by a first matrix or binder material, wherein the graphene platelets are not obtained from graphitization of the first binder or matrix material; (b) the graphene platelets have a length or width in the range of 10 nm to 10 μm; (c) the multiple solid particles are bonded by a second binder material; and (d) the first or second binder material is selected from a polymer, polymeric carbon, amorphous carbon, metal, glass, ceramic, oxide, organic material, or a combination thereof. For a lithium ion battery anode application, the first binder or matrix material is preferably amorphous carbon or polymeric carbon. Such a composite composition provides a high anode capacity and good cycling response. For a supercapacitor electrode application, the solid particles preferably have meso-scale pores therein to accommodate electrolyte.

    摘要翻译： 一种用于电化学电池电极应用的复合组合物，所述组合物包含多个固体颗粒，其中（a）固体颗粒由分散在第一基质或粘合剂材料中或由第一基质或粘合剂材料粘合的石墨烯片晶组成，其中石墨烯片晶不是从石墨烯 第一粘合剂或基质材料; （b）石墨烯片晶的长度或宽度在10nm至10μm的范围内; （c）多个固体颗粒通过第二粘合剂材料粘合; 和（d）第一或第二粘合剂材料选自聚合物，聚合物碳，无定形碳，金属，玻璃，陶瓷，氧化物，有机材料或其组合。 对于锂离子电池阳极应用，第一粘合剂或基质材料优选为无定形碳或聚合碳。 这种复合组合物提供高阳极容量和良好的循环响应。 对于超级电容器电极应用，固体颗粒优选在其中具有中等尺度的孔以适应电解质。