公开(公告)号：US20230157595A1

公开(公告)日：2023-05-25

申请号：US18159205

申请日：2023-01-25

Applicant: Medtronic, Inc.

Inventor： David Probst ,  Randal Schulhauser ,  Patrick W. Kinzie ,  Jadin C. Jackson ,  Daniel Hahn

IPC: A61B5/1468 ,  A61B5/00 ,  A61N1/05 ,  A61K31/662 ,  A61M5/142 ,  A61N1/36

CPC classification number: A61B5/1468 ,  A61B5/4839 ,  A61B5/742 ,  A61N1/0534 ,  A61K31/662 ,  A61M5/142 ,  A61N1/36139 ,  A61M2005/14208

Abstract: An enzymatic sensor configured to determine the concentration of levodopa present in a sample according to a current or a resonant frequency produced in response to levodopa interactions with L-amino acid decarboxylase present in the sensor. A processor associated with the sensor determines levodopa concentration and produces dose recommendation or output according to levodopa concentration.

公开(公告)号：US11623102B2

公开(公告)日：2023-04-11

申请号：US16050928

申请日：2018-07-31

Applicant: Medtronic, Inc.

Inventor： Randal C. Schulhauser ,  Jian Cao ,  David Probst ,  Daniel Hahn ,  Eric C. Maass ,  Patrick W. Kinzie

IPC: A61N1/39 ,  A61B5/00 ,  A61B5/145 ,  A61N1/04 ,  A61B5/021 ,  A61B5/024 ,  A61B5/08 ,  A61B5/11 ,  A61B5/369

Abstract: In some examples, an apparatus configured to be worn by a patient for cardiac defibrillation comprises sensing electrodes configured to sense a cardiac signal of the patient, defibrillation electrodes, therapy delivery circuitry configured to deliver defibrillation therapy to the patient via the defibrillation electrodes, communication circuitry configured to receive data of at least one physiological signal of the patient from at least one sensing device separate from the apparatus, a memory configured to store the data, the cardiac signal, and a machine learning algorithm, and processing circuitry configured to apply the machine learning algorithm to the data and the cardiac signal to probabilistically-determine at least one state of the patient and determine whether to control delivery of the defibrillation therapy based on the at least one probabilistically-determined patient state.