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公开(公告)号:US20240268721A1
公开(公告)日:2024-08-15
申请号:US18626074
申请日:2024-04-03
Applicant: Medtronic, Inc.
Inventor: Daniel Hahn , Akhil Srinivasan , Patrick W. Kinzie , Randal C. Schulhauser , Jennifer L. Marckmann , Mohsen Askarinya , James K. Carney , David L. Probst , Santhisagar Vaddiraju , Alejo Chavez Gaxiola , Richard J. O'Brien , Anna M. Tycon , Omid Mahdavi , Shawn C. Kelley , David A. Anderson
IPC: A61B5/1468 , A61B5/053 , A61B5/145 , A61B5/1486 , G01N27/30 , G01N27/327
CPC classification number: A61B5/1468 , A61B5/053 , A61B5/14532 , A61B5/14546 , A61B5/1486 , G01N27/301 , G01N27/3271
Abstract: Techniques are disclosed for measuring an analyte in a biological system. A system may include a medical device with an electrochemical sensor configured to sense the concentration of a plurality of analytes present in a biological system. Processing circuitry of the system may retrieve, identify, and process a respective signal from a respective work electrode to determine the concentration of a respective analyte. The system may further include an implantable medical device configured to sense a cardiac electrogram (EGM). In some examples, the system may be configured to determine one or more patient-specific relationships between the respective signals of the electrochemical sensor and the cardiac EGM during a first period of time. Based on the patient-specific relationships, the system may estimate concentrations of the one or more analytes corresponding to the respective signals based on the cardiac EGM of the patient collected over a second period of time.
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公开(公告)号:US20210290957A1
公开(公告)日:2021-09-23
申请号:US17194943
申请日:2021-03-08
Applicant: Medtronic, Inc.
Inventor: Randal C. Schulhauser , Avram Scheiner , Linnea R. Lentz
Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.
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公开(公告)号:US20200038671A1
公开(公告)日:2020-02-06
申请号:US16050928
申请日:2018-07-31
Applicant: Medtronic, Inc.
Inventor: Randal C. Schulhauser , Jian Cao , David Probst , Daniel Hahn , Eric C. Maass , Patrick W. Kinzie
IPC: A61N1/39 , A61N1/04 , A61B5/00 , A61B5/145 , A61B5/0476 , A61B5/021 , A61B5/024 , A61B5/08 , A61B5/11
Abstract: In some examples, an apparatus configured to be worn by a patient for cardiac defibrillation comprises sensing electrodes configured to sense a cardiac signal of the patient, defibrillation electrodes, therapy delivery circuitry configured to deliver defibrillation therapy to the patient via the defibrillation electrodes, communication circuitry configured to receive data of at least one physiological signal of the patient from at least one sensing device separate from the apparatus, a memory configured to store the data, the cardiac signal, and a machine learning algorithm, and processing circuitry configured to apply the machine learning algorithm to the data and the cardiac signal to probabilistically-determine at least one state of the patient and determine whether to control delivery of the defibrillation therapy based on the at least one probabilistically-determined patient state.
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公开(公告)号:US11865341B2
公开(公告)日:2024-01-09
申请号:US18180705
申请日:2023-03-08
Applicant: Medtronic, Inc.
Inventor: Randal C. Schulhauser , Avram Scheiner , Linnea R. Lentz
CPC classification number: A61N1/3606 , A61B5/053 , A61B5/0816 , A61B5/318 , A61B5/4818 , A61N1/0548 , A61N1/0551 , A61N1/3614 , A61B2562/0219
Abstract: An example method includes receiving one or more physiological signals; detecting an apnea event based on the one or more physiological signals; determining that the apnea event cannot be characterized as one of a normal, OSA (obstructive sleep apnea), CSA (central sleep apnea), or combination OSA/CSA event; and outputting an electrical stimulation as a default based on determining that the apnea event cannot be characterized as a normal event, an OSA event, a CSA event, or combination OSA/CSA events.
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公开(公告)号:US20230404446A1
公开(公告)日:2023-12-21
申请号:US18460271
申请日:2023-09-01
Applicant: Medtronic, Inc.
Inventor: Daniel Hahn , Mohsen Askarinya , James K. Carney , Patrick W. Kinzie , Jennifer Lorenz Marckmann , Randal C. Schulhauser , Santhisagar Vaddiraju , Akhil Srinivasan , David Probst , Alejo Chavez Gaxiola
IPC: A61B5/1468 , A61B5/053 , A61B5/145
CPC classification number: A61B5/1468 , A61B5/053 , A61B5/14532 , A61B5/14546 , A61B5/1486
Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.
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公开(公告)号:US20230293024A1
公开(公告)日:2023-09-21
申请号:US18163175
申请日:2023-02-01
Applicant: Medtronic, Inc.
Inventor: Elise J. Higgins , Yong K. Cho , Richard J. O’Brien , David J. Miller , Rhea M. May , Cynthia C. Barber , Randal C. Schulhauser , Sarah J. Yoon , Heather I. Tuccolo
IPC: A61B5/0205 , A61B5/1455 , A61B5/389 , A61B5/145 , A61B5/00 , A61B5/0537 , A61B5/28 , A61B5/296 , A61B10/00
CPC classification number: A61B5/02055 , A61B5/0537 , A61B5/14532 , A61B5/14551 , A61B5/28 , A61B5/296 , A61B5/389 , A61B5/4227 , A61B5/4356 , A61B5/7475 , A61B10/0012 , A61B5/0245
Abstract: A system for sensing one or more physiological traits and obstetric conditions, such as a fertility phase, pregnancy, labor, post-partum conditions, and other conditions related to the reproductive system of the patient. The system may use the one or more physiological traits sensed to define one or more patient attributes for the patient, such as a hormone level, heart rate, blood pressure, respiration rate, temperature, oxygen saturation level, uterine contractions, fluid level, and/or other patient attributes. The system is configured to compare the one or more patient attributes to one or more attribute signs describing a threshold for the one or more patient attributes. The system is configured to issue a communication to the patient and/or a clinician based on the comparisons. The system may be configured to assess and indicate reproductive phases for the patient over a life-cycle from the fertility phase to the post-partum phase.
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公开(公告)号:US20230309832A1
公开(公告)日:2023-10-05
申请号:US17999986
申请日:2021-05-28
Applicant: MEDTRONIC, INC.
Inventor: Peter N. Braido , Randal C. Schulhauser , Richard J. O'Brien , Anthony W. Rorvick , Zhongping Yang , Nicolas Coulombe , David A. Anderson , Angela M. Liu , Robert Kowal , Brian D. Pederson , Angela N. Burgess , Shinichi J. Takayama
CPC classification number: A61B5/0035 , A61B5/0044 , A61B18/1492 , A61B5/068 , A61B5/0036
Abstract: Novel tools and techniques are provided for presenting patient information to a user. In some embodiments, a computer system may: receive device data associated with one or more devices configured to perform a cardiac shunting procedure to change a cardiac blood flow pattern to improve cardiac blood flow efficiency or cardiac pumping efficiency; receive one or more imaging data associated with one or more imaging devices configured to generate images of one or more internal portions of the patient; analyze the device data and the imaging data; map the device data and the imaging data to a multi-dimensional representation of the one or more internal portions of the patient; generate one or more image-based outputs based at least in part on the mapping; and present, using a user experience (“UX”) device, the generated one or more image-based outputs.
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公开(公告)号:US20230241391A1
公开(公告)日:2023-08-03
申请号:US18068932
申请日:2022-12-20
Applicant: Medtronic, Inc.
Inventor: Avram Scheiner , Randal C. Schulhauser , Becky L. Dolan
CPC classification number: A61N1/3611 , A61N1/36139 , A61N1/37235 , A61N1/36514
Abstract: An implantable medical device (IMD) includes therapy delivery circuitry, sensing circuitry, and processing circuitry. The processing circuitry is configured to determine one or more sleep apnea therapy parameters, control the therapy delivery circuitry to deliver sleep apnea therapy via a first set of electrodes implantable within the patient in accordance with the one or more sleep apnea therapy parameters, and at least one of: (1) monitor a cardiac signal sensed with the sensing circuitry, or (2) determine one or more cardiac therapy parameters, and control the therapy delivery circuitry to deliver cardiac therapy via a second set of electrodes implantable within the patient in accordance with the one or more cardiac therapy parameters.
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公开(公告)号:US20230218899A1
公开(公告)日:2023-07-13
申请号:US18180705
申请日:2023-03-08
Applicant: Medtronic, Inc.
Inventor: Randal C. Schulhauser , Avram Scheiner , Linnea R. Lentz
CPC classification number: A61N1/3606 , A61B5/318 , A61B5/4818 , A61N1/0551 , A61N1/0548 , A61B5/053 , A61N1/3614 , A61B5/0816 , A61B2562/0219
Abstract: An example method includes receiving one or more physiological signals; detecting an apnea event based on the one or more physiological signals; determining that the apnea event cannot be characterized as one of a normal, OSA (obstructive sleep apnea), CSA (central sleep apnea), or combination OSA/CSA event; and outputting an electrical stimulation as a default based on determining that the apnea event cannot be characterized as a normal event, an OSA event, a CSA event, or combination OSA/CSA events.
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公开(公告)号:US20230001200A1
公开(公告)日:2023-01-05
申请号:US17930645
申请日:2022-09-08
Applicant: Medtronic, Inc.
Inventor: Randal C. Schulhauser , Avram Scheiner , Linnea R. Lentz
Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.
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