公开(公告)号：US20210052798A1

公开(公告)日：2021-02-25

申请号：US17093964

申请日：2020-11-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/14 ,  A61M1/28

Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.

公开(公告)号：US10905816B2

公开(公告)日：2021-02-02

申请号：US13757794

申请日：2013-02-02

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61M1/16 ,  A61M1/34

Abstract: Systems and methods for managing the sodium concentration of a dialysate fluid during hemodialysis therapy and adjusting sodium concentration using a sodium management system to generate a sodium-modified fluid are provided. The systems and methods also provide a mechanism for controlled addition of sodium ions to the dialysate to generate a predetermined total sodium concentration in a dialysate.

公开(公告)号：US10744249B2

公开(公告)日：2020-08-18

申请号：US16106116

申请日：2018-08-21

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber ,  Mark F. Daniels

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36

Abstract: Systems and methods for cleaning and disinfecting a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The system has a base module that has at least one segment of a controlled compliant flow path and at least one pair of jumpered ports configured on the base module. One or more components have connections connectable to the jumpered ports of the base module to provide for fluid communication between the segment of the controlled compliant flow path in the base module and a flow path defined by the one or more components. The base module is connected to the one or more components that define a flow path configurable for carrying out in part at least one function performed during any one of hemodialysis, hemodiafiltration or hemofiltration.

公开(公告)号：US20200179583A1

公开(公告)日：2020-06-11

申请号：US16691686

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/28

Abstract: The invention relates to devices, systems, and methods for performing a precision or personalized Peritoneal Dialysis (PD) therapy session or cycle based on dialysis adequacy measurements in patients undergoing peritoneal dialysis treatment. The settings for the precision peritoneal dialysis therapy session can be obtained using one or more flow sensors and one or more uremic solute sensors that measure the uremic solute concentration and volume of the peritoneal dialysate removed from the patient. The desired dialysis adequacy for a specific patient, group of patients, or class of patients, can then be calculated based on the measured peritoneal dialysate concentration and volume. Using the calculated dialysis adequacy, the system and methods can then set one or more peritoneal dialysis parameters for subsequent cycles or sessions.

公开(公告)号：US20200054807A1

公开(公告)日：2020-02-20

申请号：US16435976

申请日：2019-06-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/16

Abstract: The invention relates to devices, systems, and methods for preforming a precision dialysis therapy session based on an analysis of an effluent from a zirconium phosphate sorbent module during an ammonium removal process. The settings for the precision dialysis therapy session can be obtained by estimating a patient's physiological state, such as BUN level, based on the analysis of the effluent for a particular sorbent module linked to a particular patient.

公开(公告)号：US10561776B2

公开(公告)日：2020-02-18

申请号：US14555414

申请日：2014-11-26

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/36 ,  A61M1/34

Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.

公开(公告)号：US10532142B2

公开(公告)日：2020-01-14

申请号：US15651369

申请日：2017-07-17

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: A61M1/16 ,  B01D15/36 ,  B01J47/012 ,  A61M1/36 ,  A61M1/28 ,  A61M1/34 ,  B01D15/08 ,  B01J39/10 ,  B01J39/12 ,  B01J39/18 ,  B01J41/10 ,  B01J41/12 ,  B01J47/026 ,  B01J47/14 ,  B01J20/04 ,  B01J20/06 ,  B01J20/08 ,  B01J20/20 ,  B01J20/02 ,  B01J20/28

Abstract: A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.

公开(公告)号：US20190291079A1

公开(公告)日：2019-09-26

申请号：US16435772

申请日：2019-06-10

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.

公开(公告)号：US20190038824A1

公开(公告)日：2019-02-07

申请号：US16154755

申请日：2018-10-09

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: A61M1/16 ,  B01D15/36 ,  B01D15/08 ,  A61M1/34 ,  A61M1/28 ,  A61M1/14

Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.

公开(公告)号：US10124274B2

公开(公告)日：2018-11-13

申请号：US14644576

申请日：2015-03-11

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01D15/20 ,  A61M1/16

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.