Process for the direct synthesis of organotin compounds and their use
    11.
    发明授权
    Process for the direct synthesis of organotin compounds and their use 失效
    用于直接合成有机锡化合物的方法及其用途

    公开(公告)号:US5258531A

    公开(公告)日:1993-11-02

    申请号:US860507

    申请日:1992-06-17

    IPC分类号: B01J31/02 C07B61/00 C07F7/22

    CPC分类号: C07F7/2216

    摘要: The invention relates to a process for the direct synthesis of organotin compounds of the formulaR.sub.n SnCl.sub.4-nwhereinn=1-4, and,R=a linear or branched or cycloaliphatic alkyl having 4-18 C atoms,by reacting metallic tin with alkyl chlorides, characterized in that the reaction is carried out in the presence of amines of the general formulaA) R.sup.1.sub.a N [(CH.sub.2 CH.sub.2 O).sub.m CH.sub.2 CH.sub.2 OR.sup.2 ].sub.3-a and/or ammonium chlorides of the formulaB) R.sup.1.sub.b N [(CH.sub.2 CH.sub.2 O).sub.m CH.sub.2 CH.sub.2 OR.sup.2 ].sub.4-b.sup.Clwhereina=0, 1 or 2;b=0, 1, 2 or 3;R.sup.1 =linear or branched or cycloaliphatic alkyl having 2 to 24 C atoms, aryl, alkyl aryl or substituted aryl and, if a=2, or b=2 or 3, the R.sup.1 groups may be the same or different;R.sup.2 =H, linear or branched alkyl having 1 to 20 C. atoms, aryl, substituted aryl or alkyl aryl; andm=1-20.

    摘要翻译: PCT No.PCT / EP90 / 02219 Sec。 371日期:1992年6月17日 102(e)日期1992年6月17日PCT 1990年12月17日PCT PCT。 公开号WO91 / 09039 日本1991年6月27日。本发明涉及直接合成式RnSnCl4-n的有机锡化合物的方法,其中n = 1-4,并且R =具有4-18个C原子的直链或支链或脂环族烷基 通过使金属锡与烷基氯反应,其特征在于反应在通式为A)的胺存在下进行:R1aN [(CH2CH2O)mCH2CH2OR2] 3-a和/或式B的铵氯化物)R1bN [ (CH 2 CH 2 O)mCH 2 CH 2 OR 2] 4-bCl其中a = 0,1或2; b = 0,1,2或3; R1 =具有2至24个C原子的直链或支链或脂环族烷基,芳基,烷基芳基或取代芳基,如果a = 2或b = 2或3,则R1基团可以相同或不同; R2 = H,具有1至20个C原子的直链或支链烷基,芳基,取代的芳基或烷基芳基; m = 1-20。

    INTRA-AORTIC RENAL DRUG DELIVERY CATHETER
    12.
    发明申请
    INTRA-AORTIC RENAL DRUG DELIVERY CATHETER 审中-公开
    INTRA-AORTIC肾脏药物输送管

    公开(公告)号:US20080103442A1

    公开(公告)日:2008-05-01

    申请号:US11968237

    申请日:2008-01-02

    IPC分类号: A61M31/00 A61M29/02

    摘要: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.

    摘要翻译: 用于将治疗剂或诊断剂递送到主要血管的分支金黄色血管的导管包括细长轴,其具有至少一个内腔,其与所述轴的远侧部分中的药剂输送端口流体连通,所述可扩张管状构件 所述轴的远端部分和所述管状部件上的径向可扩张部件。 管状构件构造成在分支容器的上游和下游的血管内延伸,并且具有在血管内可径向扩张的内部通道,以将通过血管的血液分离成外部血流 管状构件的外部和管状构件的内部通道内的内部血流。

    Debulking catheters and methods
    15.
    发明申请
    Debulking catheters and methods 有权
    去污导管和方法

    公开(公告)号:US20050222663A1

    公开(公告)日:2005-10-06

    申请号:US11012876

    申请日:2004-12-14

    摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.

    摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。 该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。