公开(公告)号：US5353859A

公开(公告)日：1994-10-11

申请号：US944487

申请日：1992-09-14

申请人： John Oltahfer ,  Glenn Nicol ,  David Noon ,  David Leppert ,  Mark Ungs ,  Peter S. Schulte ,  Richard J. Dunkin

发明人： John Oltahfer ,  Glenn Nicol ,  David Noon ,  David Leppert ,  Mark Ungs ,  Peter S. Schulte ,  Richard J. Dunkin

IPC分类号： E05B47/02 ,  E05B65/00 ,  E06B9/56 ,  E06B9/58 ,  E06B9/70 ,  E06B9/80 ,  E06B9/82

CPC分类号： E05B47/023 ,  E05B47/0002 ,  E05B65/0021 ,  E06B9/56 ,  E06B9/581 ,  E06B9/70 ,  E06B9/82 ,  E05B47/0004 ,  E06B2009/585 ,  E06B2009/689

摘要： A roller door apparatus is provided that includes a roller means and a means journalling the roller means for reversible rotation about a central longitudinal roller axis. The roller door also includes end rail means for a reciprocal linear movement between a first position adjacent the roller means and a second position away from the roller means. Also included is a flexible curtain means with one end attached to the end rail means and the other end attached to the roller means, such that the curtain means closes a door opening with the end rail means in the second position. The curtain means winds onto the roller means when the end rail moves from the second position to the first position and vice versa. The roller door further includes a reversible electric drive motor means coupled to the roller means, and an electrical control means for controlling the drive means during movement of the end rail means for rapid acceleration of the curtain means during an initial portion of each movement, and for control of declaration of the curtain means to zero velocity during a final portion of each movement.

摘要翻译： 提供了一种滚子门装置，其包括滚子装置和一个装置，用于支撑滚子装置，用于围绕中央纵向滚轴轴线可逆地旋转。 辊门还包括用于在与辊装置相邻的第一位置和远离辊装置的第二位置之间的往复线性运动的端轨装置。 还包括柔性帘式装置，其一端连接到端轨装置，另一端连接到辊装置，使得帘式装置关闭具有端轨装置的第二位置的门开口。 当端轨从第二位置移动到第一位置时，帘子意味着卷绕到辊装置上，反之亦然。 辊门还包括联接到辊装置的可逆电驱动马达装置，以及用于在端轨装置运动期间控制驱动装置的电控制装置，用于在每次运动的初始部分期间快速加速幕装置;以及 用于控制帘幕的声明意味着在每次移动的最后部分期间零速度。

公开(公告)号：US09242081B2

公开(公告)日：2016-01-26

申请号：US13231807

申请日：2011-09-13

申请人： William Drasler ,  Wesley Pedersen ,  Mark Ungs

发明人： William Drasler ,  Wesley Pedersen ,  Mark Ungs

IPC分类号： A61M31/00 ,  A61B5/00 ,  A61M29/02 ,  A61M25/10

CPC分类号： A61M29/02 ,  A61M25/1002 ,  A61M25/104 ,  A61M2025/1059 ,  A61M2025/1072 ,  A61M2025/1084

摘要： In one embodiment, a balloon catheter is provided for use during annuloplasty. Preferably, the balloon includes a distal, noncompliant portion and a proximal semi-compliant portion which allows for sequential inflation, reliable positioning, and compliance measurement.

摘要翻译： 在一个实施例中，提供气囊导管用于瓣环成形术期间。 优选地，气囊包括远侧不合格部分和近侧半柔顺部分，其允许顺序充气，可靠的定位和顺应性测量。

公开(公告)号：US20060263339A1

公开(公告)日：2006-11-23

申请号：US11406508

申请日：2006-04-18

申请人： Mark Poznansky ,  Traci Goodchild ,  Mark Ungs ,  Nicholas Chronos ,  Nadine Weich

发明人： Mark Poznansky ,  Traci Goodchild ,  Mark Ungs ,  Nicholas Chronos ,  Nadine Weich

IPC分类号： A61K35/14 ,  C12N5/08

CPC分类号： A61K35/17 ,  A61K2035/124 ,  C12N5/0635

摘要： The present invention relates generally to systems and methods of enhancing recovery of function of injured tissue through administration of a composition comprising a relatively pure populations of B lymphocyte cells in a pharmaceutically acceptable carrier to the injured tissue. Kits are provided to aid in purification of B cells from heterogeneous mixtures of cells and administration of B cells to injured tissue.

公开(公告)号：US20050267517A1

公开(公告)日：2005-12-01

申请号：US11184644

申请日：2005-07-19

申请人： Mark Ungs

发明人： Mark Ungs

IPC分类号： A61B17/22 ,  A61B17/00 ,  A61F2/01 ,  A61M25/00 ,  A61M29/00

CPC分类号： A61F2/01 ,  A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/0078

摘要： Distal protection filter and method of using the same. A distal protection filter may be coupled to an elongate shaft. The filter includes a filter material coupled to a filter frame. The shape of the filter may be generally cylindrical or disc shaped. The filter material may capture embolic debris generated during an intravascular intervention.

公开(公告)号：US20050042254A1

公开(公告)日：2005-02-24

申请号：US10892518

申请日：2004-07-15

申请人： Toby Freyman ,  Maria Palasis ,  Mark Ungs

发明人： Toby Freyman ,  Maria Palasis ,  Mark Ungs

IPC分类号： A61K35/12 ,  A61L27/36 ,  A61L27/54 ,  A61L27/60 ,  C12N5/00 ,  C12N5/02 ,  C12N5/071 ,  C12N5/077 ,  A61F2/00

CPC分类号： C12N5/00 ,  A61K35/12 ,  A61L27/3604 ,  A61L27/367 ,  A61L27/54 ,  A61L27/60 ,  A61L2300/252 ,  A61L2300/254 ,  A61L2300/256 ,  A61L2300/414 ,  A61L2300/426 ,  A61L2300/43 ,  A61L2300/604 ,  C12N5/0068 ,  C12N5/0657 ,  C12N5/0698 ,  C12N2502/094 ,  C12N2502/1323 ,  C12N2533/74 ,  C12N2533/92 ,  C12N2535/10

摘要： The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly useful for regeneration and repair of cardiac tissue. The scaffold contains layers of alternating A-strips and S-strips, wherein the A-strips within each layer are aligned parallel to each other and preferentially promote cellular attachment over attachment to the S-strips. Methods of producing and implanting the scaffold are also provided.

摘要翻译： 本发明涉及生物相容的三维支架，其可用于生长细胞并且以预定取向再生或修复组织。 支架对心脏组织的再生和修复特别有用。 支架包含交替的A带和S带的层，其中每层内的A带彼此平行对准，并优先促进通过附着到S带的细胞附着。 还提供了生产和植入支架的方法。

公开(公告)号：US07951111B2

公开(公告)日：2011-05-31

申请号：US12576970

申请日：2009-10-09

申请人： William Drasler ,  Wes Pedersen ,  Mark Ungs

发明人： William Drasler ,  Wes Pedersen ,  Mark Ungs

IPC分类号： A61M31/00 ,  A61M37/00 ,  A61M29/00

CPC分类号： A61M25/1002 ,  A61B17/22012 ,  A61B2017/22098 ,  A61M25/1011 ,  A61M25/10186 ,  A61M25/10188 ,  A61M25/1029 ,  A61M29/02 ,  A61M2025/0002 ,  A61M2025/1031 ,  A61M2025/1047 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088

摘要： A valvuloplasty catheter has a dog-bone shaped balloon with semi-compliant smaller diameter waist and non-compliant larger diameter bulbous end regions. The balloon centers across the valve with the waist adjacent to the annulus. One bulbous region serves to hyperextend the valve leaflets and the other assists in stabilizing the balloon position to reduce migration. The semi-compliant waist increases in diameter as fluid enters the balloon until it comes into contact with the valve annulus. The pressure within the balloon per unit of volume delivery has a greater slope after contact with the annulus than before resulting in a change in slope for the pressure versus volume curve. The diameter of the balloon and annulus are determined at this inflection point when the balloon contacts the annulus.

摘要翻译： 瓣膜成形术导管具有具有半顺应性较小直径的腰部和非顺应性较大直径球形末端区域的狗骨形气囊。 气囊穿过瓣膜，腰围与环带相邻。 一个球茎区域用于过度扩张瓣叶，另一个有助于稳定气囊位置以减少迁移。 随着流体进入气囊直到与阀环接触，半顺应性腰部直径增加。 每单位体积输送中气囊内的压力与空气接触之后具有比之前更大的斜率，导致压力与体积曲线的斜率变化。 当球囊接触环形空间时，在该拐点处确定球囊和环的直径。

公开(公告)号：US07579189B2

公开(公告)日：2009-08-25

申请号：US12111482

申请日：2008-04-29

申请人： Toby Freyman ,  Maria Palasis ,  Mark Ungs

发明人： Toby Freyman ,  Maria Palasis ,  Mark Ungs

IPC分类号： C12N5/00 ,  A61K9/00

CPC分类号： C12N5/00 ,  A61K35/12 ,  A61L27/3604 ,  A61L27/367 ,  A61L27/54 ,  A61L27/60 ,  A61L2300/252 ,  A61L2300/254 ,  A61L2300/256 ,  A61L2300/414 ,  A61L2300/426 ,  A61L2300/43 ,  A61L2300/604 ,  C12N5/0068 ,  C12N5/0657 ,  C12N5/0698 ,  C12N2502/094 ,  C12N2502/1323 ,  C12N2533/74 ,  C12N2533/92 ,  C12N2535/10

摘要： The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly useful for regeneration and repair of cardiac tissue. The scaffold contains layers of alternating A-strips and S-strips, wherein the A-strips within each layer are aligned parallel to each other and preferentially promote cellular attachment over attachment to the S-strips. Methods of producing and implanting the scaffold are also provided.

摘要翻译： 本发明涉及生物相容的三维支架，其可用于生长细胞并且以预定取向再生或修复组织。 支架对心脏组织的再生和修复特别有用。 支架包含交替的A带和S带的层，其中每层内的A带彼此平行对准，并优先促进通过附着到S带的细胞附着。 还提供了生产和植入支架的方法。

公开(公告)号：US08900264B2

公开(公告)日：2014-12-02

申请号：US13108938

申请日：2011-05-16

申请人： William Drasler ,  Wes Pedersen ,  Mark Ungs

发明人： William Drasler ,  Wes Pedersen ,  Mark Ungs

IPC分类号： A61M29/00 ,  A61M29/02 ,  A61M37/00 ,  A61M31/00 ,  A61M25/10 ,  A61B17/22 ,  A61M25/00

CPC分类号： A61M25/1002 ,  A61B17/22012 ,  A61B2017/22098 ,  A61M25/1011 ,  A61M25/10186 ,  A61M25/10188 ,  A61M25/1029 ,  A61M29/02 ,  A61M2025/0002 ,  A61M2025/1031 ,  A61M2025/1047 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088

摘要： A valvuloplasty catheter has a dog-bone shaped balloon with semi-compliant smaller diameter waist and non-compliant larger diameter bulbous end regions. The balloon centers across the valve with the waist adjacent to the annulus. One bulbous region serves to hyperextend the valve leaflets and the other assists in stabilizing the balloon position to reduce migration. The semi-compliant waist increases in diameter as fluid enters the balloon until it comes into contact with the valve annulus. The pressure within the balloon per unit of volume delivery has a greater slope after contact with the annulus than before resulting in a change in slope for the pressure versus volume curve. The diameter of the balloon and annulus are determined at this inflection point when the balloon contacts the annulus.

摘要翻译： 瓣膜成形术导管具有具有半顺应性较小直径的腰部和非顺应性较大直径球形末端区域的狗骨形气囊。 气囊穿过瓣膜，腰围与环带相邻。 一个球茎区域用于过度扩张瓣叶，另一个有助于稳定气囊位置以减少迁移。 随着流体进入气囊直到与阀环接触，半顺应性腰部直径增加。 每单位体积输送中气囊内的压力与空气接触之后具有比之前更大的斜率，导致压力与体积曲线的斜率变化。 当球囊接触环形空间时，在该拐点处确定球囊和环的直径。

公开(公告)号：US20110218564A1

公开(公告)日：2011-09-08

申请号：US13108938

申请日：2011-05-16

申请人： William Drasler ,  Wes Pedersen ,  Mark Ungs

发明人： William Drasler ,  Wes Pedersen ,  Mark Ungs

IPC分类号： A61M29/00

CPC分类号： A61M25/1002 ,  A61B17/22012 ,  A61B2017/22098 ,  A61M25/1011 ,  A61M25/10186 ,  A61M25/10188 ,  A61M25/1029 ,  A61M29/02 ,  A61M2025/0002 ,  A61M2025/1031 ,  A61M2025/1047 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088

摘要： A valvuloplasty catheter has a dog-bone shaped balloon with semi-compliant smaller diameter waist and non-compliant larger diameter bulbous end regions. The balloon centers across the valve with the waist adjacent to the annulus. One bulbous region serves to hyperextend the valve leaflets and the other assists in stabilizing the balloon position to reduce migration. The semi-compliant waist increases in diameter as fluid enters the balloon until it comes into contact with the valve annulus. The pressure within the balloon per unit of volume delivery has a greater slope after contact with the annulus than before resulting in a change in slope for the pressure versus volume curve. The diameter of the balloon and annulus are determined at this inflection point when the balloon contacts the annulus.

摘要翻译： 瓣膜成形术导管具有具有半顺应性较小直径的腰部和非顺应性较大直径球形末端区域的狗骨形气囊。 气囊穿过瓣膜，腰围与环带相邻。 一个球茎区域用于过度扩张瓣叶，另一个有助于稳定气囊位置以减少迁移。 随着流体进入气囊直到与阀环接触，半顺应性腰部直径增加。 每单位体积输送中气囊内的压力与空气接触之后具有比之前更大的斜率，导致压力与体积曲线的斜率变化。 当球囊接触环形空间时，在该拐点处确定球囊和环的直径。

公开(公告)号：US20100132894A1

公开(公告)日：2010-06-03

申请号：US12325944

申请日：2008-12-01

申请人： Perry W. Knutson ,  Mark Ungs

发明人： Perry W. Knutson ,  Mark Ungs

IPC分类号： E06B3/48

CPC分类号： E06B9/13 ,  E06B2009/17069 ,  F25D23/021

摘要： An example of a vertically operating door includes a flexible panel comprising two pliable sheets of material with a plurality of pads or mats of thermal insulation between the two sheets. In some examples, a plurality of horizontally elongate baffles made of pliable strips of material are installed between the two sheets. The baffles effectively divide one large interior volume between the sheets into more manageable smaller volumes or chambers. The baffles restrict the air between the sheets from being forced to the bottom of the panel as the panel ascends and bends across an overhead roller. Without the baffles and smaller chambers, the panel sheets in the area near the bottom of the panel would tend to bulge outward as the door opens.

摘要翻译： 垂直操作的门的示例包括柔性面板，其包括两个柔韧的材料片材，在两个片材之间具有多个隔热垫或垫。 在一些实例中，由两个片材之间安装由柔韧材料条制成的多个水平细长的挡板。 挡板有效地将纸张之间的一个大的内部容积分成更易于管理的较小体积或室。 挡板限制板之间的空气在面板上升并弯曲穿过高架辊时被强制到面板的底部。 没有挡板和较小的腔室，靠近面板底部区域的面板在门打开时会向外凸出。