公开(公告)号：US5938940A

公开(公告)日：1999-08-17

申请号：US95189

申请日：1998-06-10

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: A61M1/02 ,  A61M1/36 ,  B01D19/00 ,  B01D29/00 ,  B01D29/01 ,  B01D29/92 ,  B01D35/02 ,  B01D36/00 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  B01D65/00 ,  B01D37/00

CPC classification number: A61M1/3633 ,  A61M1/3627 ,  A61M1/3643 ,  A61M1/3652 ,  B01D19/0031 ,  B01D29/012 ,  B01D36/001 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  B01D63/087 ,  B01D65/00 ,  A61M2202/0439 ,  A61M2205/7527 ,  A61M2206/12

Abstract: An in-line liquid filtration device useable for filtration of blood, blood products or the like includes a housing having an inlet port, an outlet port, at least one filter element disposed in the housing between the inlet port and outlet port so as to filter liquid which flows into the filtration device via the inlet port. The filter element divides the housing into a first chamber and a second chamber. The device allows gases to vent the filtration device through the outlet port. The means may include a flow deflector within the first chamber and/or the second chamber. The means may also include a channel, preferably spiral, within either the first chamber and/or second chamber. The filtration device allows air therein to be purged downstream into either an air collecting bag or into the blood receiving bag without the manipulation of the height of the filtration device or the blood receiving bag.

Abstract translation: 可用于血液，血液制品等的过滤的在线液体过滤装置包括具有入口端口，出口端口，设置在入口端口和出口端口之间的壳体中的至少一个过滤元件的壳体，以便过滤 通过入口流入过滤装置的液体。 过滤元件将壳体分成第一室和第二室。 该装置允许气体通过出口端口排出过滤装置。 该装置可以包括在第一室和/或第二室内的导流器。 该装置还可以包括在第一室和/或第二室内的通道，优选地是螺旋的。 过滤装置允许其中的空气在下游进入空气收集袋或进入血液接收袋中，而不用操纵过滤装置或血液接收袋的高度。

公开(公告)号：US5902490A

公开(公告)日：1999-05-11

申请号：US680674

申请日：1996-07-16

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: A61M1/36 ,  B01D19/00 ,  B01D36/00 ,  B01D46/00 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  B01D37/00 ,  B01D35/00

CPC classification number: B01D63/087 ,  A61M1/3627 ,  A61M1/3633 ,  A61M1/3643 ,  A61M1/3652 ,  B01D19/0031 ,  B01D36/001 ,  B01D46/0012 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  A61M2202/0439 ,  A61M2205/7527 ,  A61M2205/7536

Abstract: The filtration method involves processing biological liquid from an enclosed flexible supply bag to a filtration media within a processing system wherein the flow of biological liquid within the system is restricted to allow the biological liquid to back up above the level of a port located upstream within the system and preventing gas from entering into the processing system through the port by maintaining the level of biological liquid above the port until the flow of biological liquid from the flexible supply bag ceases. The system automatically allows gas to enter into the system through the port when the flow of biological liquid ceases thereby draining the biological liquid into a receiving bag. The flow may be restricted by a narrow cross-sectional area within the processing system and the port may be covered by a hydrophobic filter media.

Abstract translation: 过滤方法包括将生物液体从封闭的柔性供应袋处理到处理系统内的过滤介质，其中系统内的生物液体的流动受到限制，以允许生物液体回到高于位于 系统，并通过将端口上方的生物液体的水平维持，直到来自柔性供应袋的生物液体的流动停止，从而防止气体通过端口进入处理系统。 当生物液体的流动停止时，系统自动允许气体通过端口进入系统，从而将生物液体排放到接收袋中。 流动可以由处理系统内的窄横截面积限制，并且端口可被疏水性过滤介质覆盖。

公开(公告)号：US5472605A

公开(公告)日：1995-12-05

申请号：US209523

申请日：1994-03-10

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: A61M1/36 ,  B01D19/00 ,  B01D36/00 ,  B01D46/00 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  B01D29/00 ,  B01D35/01

CPC classification number: B01D63/087 ,  A61M1/3627 ,  A61M1/3633 ,  A61M1/3643 ,  A61M1/3652 ,  B01D19/0031 ,  B01D36/001 ,  B01D46/0012 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  A61M2202/0439 ,  A61M2205/7527 ,  A61M2205/7536

Abstract: A liquid filtration device useable for removing leukocytes from blood contains a first chamber which is in fluid flow relationship with a second chamber. Filtration elements separate the first chamber from the second chamber so that liquid flowing from the first chamber is filtered thereby prior to entry into the second chamber. A passage leads from the second chamber into the first chamber and a hydrophobic filter may be used to prevent liquid from the first chamber from flowing through the passage into the second chamber while allowing air to flow therethrough. An outlet is located in the second chamber, preferably at the bottom thereof. A second outlet may be located within the second chamber and may be placed in fluid flow relationship therewith by a conduit or the like.

公开(公告)号：US5234585A

公开(公告)日：1993-08-10

申请号：US811473

申请日：1991-12-19

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D29/01 ,  B01D29/05 ,  B01D29/60 ,  B01D35/30

CPC classification number: B01D29/05 ,  B01D2201/204

Abstract: The vacuum filtration device has a disposable filter funnel and a disposable filtrate receptacle. The funnel and receptacle are used with a reusable base that is connected to a vacuum source. When the receptacle and funnel are mounted on the base the vacuum is applied through a connecting passage to the receptacle to draw the filtrate from the funnel into the receptacle.

Abstract translation: 真空过滤装置具有一次性过滤漏斗和一次性滤液容器。 漏斗和插座与可重复使用的基座一起使用，该基座连接到真空源。 当容器和​​漏斗安装在基座上时，真空通过连接通道施加到容器，以将滤液从漏斗抽入容器中。

公开(公告)号：US08158009B2

公开(公告)日：2012-04-17

申请号：US12023685

申请日：2008-01-31

Applicant: Jeffrey F. Kane ,  Thomas Taylor ,  Peter Zuk, Jr. ,  Sean Landis Phillips

Inventor： Jeffrey F. Kane ,  Thomas Taylor ,  Peter Zuk, Jr. ,  Sean Landis Phillips

IPC: B01D35/00

CPC classification number: B01D29/05 ,  B01D29/085 ,  B01D29/925 ,  B01D29/965 ,  B01D2201/204 ,  B01L3/502 ,  B01L2300/0681 ,  B01L2400/049 ,  G01N1/4077 ,  G01N2001/4088

Abstract: A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system includes an upper sample reservoir, a filter and a lower storage bottle. A vacuum is applied below the sample filter to draw sample liquid through the sample filter into the storage bottle. A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming.

Abstract translation: 替代地或结合使用液体过滤系统的分流器，真空控制和倾斜来减少过滤的液体样品中的泡沫产生。 液体过滤系统包括上部样品储存器，过滤器和下部储存瓶。 在样品过滤器下方施加真空，将样品液体通过样品过滤器吸入储存瓶中。 流量分流器可以用于将过滤的液体样品的流动引导到存储瓶的侧壁或引导流到存储瓶的底部。 可以调节真空以减少起泡。 液体过滤系统可以倾斜以将流体引导到下储存瓶的侧壁并减少发泡。

公开(公告)号：US07798333B2

公开(公告)日：2010-09-21

申请号：US11516011

申请日：2006-09-05

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D29/085

CPC classification number: G01N1/4077 ,  B01D29/085 ,  B01D2201/204 ,  B01L3/563 ,  G01N2035/1053

Abstract: A liquid filtering system and methods for filtering are disclosed. One embodiment of the system includes a filtering apparatus having a receiving receptacle coupled with an adapter. The adapter has an adapter port for receiving a vacuum and an interface for coupling with an output receptacle that receives filtered liquid from the filtering apparatus. The adapter is between the receiving receptacle and output receptacle when the output receptacle is coupled with the adapter interface. The system also includes a base having a substantially rigid housing containing an internal vacuum channel terminating at a base vacuum delivery port. The adapter is couplable with the base to connect the adapter port to the base vacuum delivery port.

Abstract translation: 公开了一种液体过滤系统和过滤方法。 该系统的一个实施例包括具有与适配器耦合的接收容器的过滤装置。 适配器具有用于接收真空的适配器端口和用于与从过滤装置接收过滤液体的输出插座耦合的接口。 当输出插座与适配器接口耦合时，适配器位于接收插座和输出插座之间。 该系统还包括具有基本上刚性的壳体的底座，其包含终止于基底真空输送口的内部真空通道。 适配器可与基座连接，以将适配器端口连接到基本真空输送端口。

公开(公告)号：US06660171B2

公开(公告)日：2003-12-09

申请号：US09818108

申请日：2001-03-27

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D3700

CPC classification number: A61M1/3633

Abstract: A high capacity gravity feed filter for filtering blood and blood products or the like includes a body having an inlet port, an outlet port, two filter wells, at least one filter element disposed in each of said filter wells, between the inlet port and outlet port so as to filter liquid which flows into the filtration device via the inlet port. The filter elements divide each of said filter wells into a first chamber and a second chamber. The device allows gases to vent the filtration device through the outlet port. The means may include a vertical channel within each of said second chambers. The filtration device allows air therein to be purged downstream into a receiving blood bag without the manipulation of the height of the filtration device or the receiving blood bag.

公开(公告)号：US06251292B1

公开(公告)日：2001-06-26

申请号：US09434182

申请日：1999-11-04

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D3700

CPC classification number: B01D36/001 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/0231 ,  A61M1/3627 ,  A61M1/3633 ,  A61M1/3652 ,  A61M2202/0439 ,  A61M2205/7536 ,  B01D19/0031 ,  B01D61/18 ,  B01D61/20 ,  B01D63/08 ,  A61M2202/005

Abstract: An in-line gravity filtration device for biological fluids such as blood or blood products is disclosed. The device includes a series of channels formed downstream of filtration elements. The channels are defined in cross sectional area by the distance between the filtration elements and their bottoms. The channels are configured to form flow paths to an outlet port so that air within the channels is forced downstream through the outlet port thereby minimizing air being trapped on the downstream side of the device. For optimum performance, the cross section area of a single continuous channel, or the sum of the cross sectional area of parallel channels, leading to a single outlet port, should not exceed the cross sectional area of the outlet port.

Abstract translation: 公开了一种生物流体如血液或血液制品的在线重力过滤装置。 该装置包括在过滤元件下游形成的一系列通道。 通道以横截面积限定过滤元件与其底部之间的距离。 通道被配置成形成到出口的流动路径，使得通道内的空气被迫通过出口端口下游，从而最小化被捕获在设备的下游侧的空气。 为获得最佳性能，单个连续通道的横截面面积或通向单个出口的平行通道的横截面积之和应不超过出口的横截面面积。

公开(公告)号：US5948246A

公开(公告)日：1999-09-07

申请号：US104339

申请日：1993-08-09

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D29/01 ,  B01D24/38 ,  B01D29/05 ,  B01D29/60 ,  B01D29/88 ,  B01D35/30 ,  B01D36/00 ,  B01D29/085

CPC classification number: B01D29/05 ,  B01D2201/204

Abstract: The vacuum filtration device has a disposable filter funnel and a disposable filtrate receptacle. The funnel and receptacle are used with a reusable base that is connected to a vacuum source. When the receptacle and funnel are mounted on the base the vacuum is applied through a connecting passage to the receptacle to draw the filtrate from the funnel into the receptacle.

Abstract translation: 真空过滤装置具有一次性过滤漏斗和一次性滤液容器。 漏斗和插座与可重复使用的基座一起使用，该基座连接到真空源。 当容器和​​漏斗安装在基座上时，真空通过连接通道施加到容器，以将滤液从漏斗抽入容器中。

公开(公告)号：US5112484A

公开(公告)日：1992-05-12

申请号：US595533

申请日：1990-10-11

Applicant: Peter Zuk, Jr.

Inventor： Peter Zuk, Jr.

IPC: B01D29/11 ,  B01D61/18 ,  B01D63/08 ,  B01D63/16 ,  B01L3/00

CPC classification number: B01D61/18 ,  B01D29/111 ,  B01D63/082 ,  B01D63/16 ,  B01L3/502

Abstract: A filtration device for separating filtrate and concentrate from a solution may contain a variable dead stop feature. The apparatus includes a housing with a means for collecting filtrate and a multiple sided filter unit insertable within the housing. The filter unit contains a semipermeable membrane thereon for separating filtrate from concentrate and a means for directing filtrate to a discharge within the housing. The apparatus also contains a means for preventing concentrate within the housing from escaping through the discharge opening of the housing.