公开(公告)号：US20080027517A1

公开(公告)日：2008-01-31

申请号：US11773555

申请日：2007-07-05

申请人： Phillip Burwell ,  Zihong Guo ,  Jennifer Matson ,  Steven Daly ,  David Shine ,  Gary Lichttenegger ,  Jean Bishop ,  Nick Yeo ,  Hugh Narciso

发明人： Phillip Burwell ,  Zihong Guo ,  Jennifer Matson ,  Steven Daly ,  David Shine ,  Gary Lichttenegger ,  Jean Bishop ,  Nick Yeo ,  Hugh Narciso

IPC分类号： A61N5/06

CPC分类号： A61N5/0601 ,  A61B2018/2261 ,  A61N5/062 ,  A61N2005/0602 ,  A61N2005/0652 ,  A61N2005/1003

摘要： Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element. The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.

摘要翻译： 用于照射血管组织部分的光产生装置，以进行光动力疗法。 在一个实施例中，优选地包括多个发光二极管的光源阵列，聚焦透镜和光漫射元件被包括在导管的远端中。 可选地提供气囊以中断可阻挡光的传播的血流，并使装置居中在血管中。 光纤可选地将来自光源的光引导到漫射元件。 光源阵列可以具有径向或线性配置并且可以产生多于一个波长的光以激活不同的光反应剂。 线性光源元件特别适用于处理容器中组织的细长部分。 旨在用于常规气囊导管的一个实施例将光源集成到导丝中。

公开(公告)号：US20090118816A1

公开(公告)日：2009-05-07

申请号：US11991589

申请日：2006-09-05

申请人： Nicholas Kipshidze ,  Gary Lichttenegger ,  Alexander J. Pallenberg ,  Nick Yeo ,  Thomas L. Wenger

发明人： Nicholas Kipshidze ,  Gary Lichttenegger ,  Alexander J. Pallenberg ,  Nick Yeo ,  Thomas L. Wenger

IPC分类号： A61F2/06

CPC分类号： A61L31/16 ,  A61L31/14 ,  A61L2300/602 ,  A61L2300/80

摘要： A treatment system to provide energy therapy to a patient includes an implantable device and an activation system having a plurality of energy emitters that transmit energy towards the device. In one embodiment, the implantable device is a stent carrying a treatment agent. The treatment agent can be selectively activated by the activation system before, during, or after implantation in a subject's body. The activated treatment agent can react with adjacent tissues.

摘要翻译： 向患者提供能量治疗的治疗系统包括可植入装置和激活系统，该系统具有向能量传递能量的多个能量发射器。 在一个实施例中，可植入装置是承载处理剂的支架。 处理剂可以在植入人体内之前，之中或之后被激活系统选择性地活化。 活化处理剂可与相邻组织反应。