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公开(公告)号：US11896840B2
公开(公告)日：2024-02-13
申请号：US18060073
申请日：2022-11-30
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Shuai Xu , Chenkai Xu , Hao Zhang , Hangbo Zhao , John A. Rogers
CPC classification number: A61N5/0601 , A61M37/0015 , A61N5/062 , A61M2037/003 , A61M2037/0061 , A61N2005/0602 , A61N2005/063 , A61N2005/0652 , A61N2005/0661
Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.
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公开(公告)号：US20230405351A1
公开(公告)日：2023-12-21
申请号：US18332643
申请日：2023-06-09
Applicant: Alucent Biomedical Inc.
Inventor： James D. ISAACSON , RB Eugene HAYES , Dylan James BLAIR
CPC classification number: A61N5/062 , A61N5/0601 , A61L2202/24 , A61N2005/0602 , A61L2/087
Abstract: An apparatus includes a catheter including light fibers extending from a proximal section to a distal section. The apparatus may include an emission section positioned on the distal section that is coated with an NVS agent. The material of the emission section may be different from the other sections of the catheter. The apparatus can be sterilized using E-beam sterilization.
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公开(公告)号：US11786751B2
公开(公告)日：2023-10-17
申请号：US16720841
申请日：2019-12-19
Applicant: CORNING INCORPORATED
Inventor： Michael Lucien Genier , William Spencer Klubben, III
CPC classification number: A61N5/0624 , A61N5/067 , A61N2005/0602 , A61N2005/063 , A61N2005/0651 , A61N2005/0654
Abstract: A therapeutic illumination assembly includes a catheter and a point source treatment fiber. The catheter comprises a catheter wall encircling a luminal fluid pathway. The point source treatment fiber is positioned within the luminal fluid pathway of the catheter. Further, the point source treatment fiber comprises a plurality of light emitting point sources intermittently positioned along a treatment length of the point source treatment fiber such that the plurality of light emitting point sources irradiate the catheter when the plurality of light emitting point sources emit light.
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公开(公告)号：US20180079833A1
公开(公告)日：2018-03-22
申请号：US15815855
申请日：2017-11-17
Applicant: Alumend, LLC
Inventor： Ronald E. Utecht , Kaia L. Kloster , Millard M. Judy , Kevin J. Vaska , James L. Matthews
IPC: C08B37/08 , A61Q19/00 , A61Q17/04 , A61B17/00 , A61B17/08 , A61K8/73 , A61K31/722 , A61N5/06 , A61L24/08 , A61K41/00
CPC classification number: C08B37/003 , A61B17/00 , A61B17/08 , A61K8/736 , A61K31/722 , A61K41/00 , A61K41/0042 , A61K41/0057 , A61K47/61 , A61K2800/57 , A61K2800/81 , A61K2800/94 , A61L24/08 , A61N5/062 , A61N2005/0602 , A61N2005/0663 , A61Q17/04 , A61Q19/00
Abstract: Naphthalimide compounds as used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bone tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.
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公开(公告)号：US20170340896A1
公开(公告)日：2017-11-30
申请号：US15660881
申请日：2017-07-26
Applicant: ROCOMP GLOBAL, L.L.C.
Inventor： CHARLES BRIAN ROGERS , SCOTT DAVID COMPTON
CPC classification number: A61N5/0601 , A61B18/24 , A61B2018/00404 , A61B2018/2255 , A61N5/0624 , A61N2005/0602 , A61N2005/063 , A61N2005/0632 , A61N2005/0644 , A61N2005/0664
Abstract: The present application is directed to devices, assemblies, systems and methods for targeting one or more sites with electromagnetic radiation. The devices, assemblies and systems are operationally configured to transform and convey electromagnetic radiation to one or more targeted sites. The devices, assemblies and systems may also convey one or more fluids or fluid solutions to the one or more targeted sites.
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Patent Agency Ranking
公开(公告)号：US20170173349A1
公开(公告)日：2017-06-22
申请号：US14978321
申请日：2015-12-22
Applicant: DePuy Synthes Products, LLC
Inventor： Martin Pfleiderer , Philippe Margairaz , Blaise Lovisa , Yanik S. Tardy
CPC classification number: A61N5/0601 , A61B17/1695 , A61B2090/103 , A61F2/82 , A61N5/0622 , A61N2005/0602 , A61N2005/0612 , A61N2005/063 , A61N2005/0665
Abstract: An apparatus for efficient delivery of light to a target site in a human body wherein the apparatus includes a light source and at least one stent having a lumen defined longitudinally therethrough. The light source is disposed longitudinally within the lumen of the stent and/or on a surface of the stent. Also, a method for efficient delivery of phototherapy to the brain in the human body. A hole is drilled in the skull without penetrating dura matter in the brain. Each drilled hole is fitted with a transparent light conductor so that each light conductor fully penetrates the skull. Light emitted from a light source disposed on a first side exteriorly of the skull is transmitted through to an opposite side interiorly of the skull to a target site within the brain via the transparent light conductor.
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7.发明申请IMPLANTABLE MEDICAL DEVICE, SYSTEM AND METHOD FOR INDUCING THROMBOSIS IN AN ARTERY OF A LIVING ANIMAL 审中-公开可植入医疗装置，用于诱导生物动物中的血栓形成的系统和方法公开(公告)号：US20160367831A1
公开(公告)日：2016-12-22
申请号：US14742071
申请日：2015-06-17
Applicant: Chang Gung Memorial Hospital, Linkou
Inventor： Tsong-Hai Lee , Shyh-Liang Lou , Jih-Chao Yeh
IPC: A61N5/06
CPC classification number: A61N5/0601 , A61N2005/0602 , A61N2005/0626 , A61N2005/0632 , A61N2005/0651
Abstract: A method for inducing thrombosis in an artery of a living animal includes: implanting an implantable medical device into a living animal, the implantable medical device including a light-emitting element and a wireless power receiver; administrating a photo-sensitizing dye material into the living animal; and providing wirelessly a control signal, from an external power controller, to the wireless power receiver which transmits electrical power to the light-emitting element in response to the control signal to drive the light-emitting element to emit light for irradiating the artery of the living animal.
Abstract translation: 一种用于在动物动脉中引起血栓形成的方法包括：将植入式医疗装置植入到活体动物中，所述可植入医疗装置包括发光元件和无线电力接收器; 向感染动物施用光敏染料; 以及从外部功率控制器向所述无线电力接收器提供控制信号，所述无线电力接收器响应于所述控制信号而向所述发光元件发送电力，以驱动所述发光元件发射用于照射所述发光元件的动脉的光 活的动物
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公开(公告)号：US20160089547A1
公开(公告)日：2016-03-31
申请号：US14868950
申请日：2015-09-29
Applicant: TERUMO KABUSHIKI KAISHA
Inventor： Katsuhiko SHIMIZU , Yuuichi TADA , Yuuki ITOU , Kazuyuki TAKAHASHI
CPC classification number: A61N5/0601 , A61N5/0625 , A61N2005/0602 , A61N2005/063 , A61N2005/0665 , A61N2005/067 , G02B6/00 , G02B6/262
Abstract: A laser light irradiation device is disclosed, which can include an optical guide having a columnar portion and transmitting laser light through the columnar portion; a reflecting portion having a reflecting surface that reflects the laser light transmitted through the optical guide; and a transmitting portion having a window part and disposed between the columnar portion of the optical guide and the reflecting portion in such a manner that one end of the transmitting portion is in contact with the columnar portion, the transmitting portion transmitting the laser light emitted from the columnar portion to the reflecting portion and transmitting the laser light reflected by the reflecting surface to cause the laser light to be radiated to an external through the window part. A diameter of the reflecting surface gradually becomes smaller as distance from a boundary between the transmitting portion and the reflecting portion increases.
Abstract translation: 公开了一种激光照射装置，其可以包括具有柱状部分的光导，并且透射通过柱状部分的激光; 具有反射透过光导的激光的反射面的反射部; 以及透光部，其具有窗部，并且以使得所述透射部的一端与所述柱状部接触的方式配置在所述导光体的柱状部与所述反射部之间，所述透射部透射从所述透光部发出的激光 向反射部分的柱状部分，并透射由反射表面反射的激光，以使激光通过窗口部分辐射到外部。 随着与透射部分和反射部分之间的边界的距离增加，反射表面的直径逐渐变小。
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9.发明申请公开(公告)号：US20160059035A1
公开(公告)日：2016-03-03
申请号：US14933112
申请日：2015-11-05
Inventor： Karin Jarverud , Cecilia Emmanuelsson , Anders Bjorling , Kjell Noren
CPC classification number: A61N5/0613 , A61B5/0408 , A61B5/05 , A61B5/103 , A61B5/117 , A61B18/18 , A61B18/20 , A61B2018/00577 , A61N1/00 , A61N1/056 , A61N1/30 , A61N1/362 , A61N1/39 , A61N5/06 , A61N5/0603 , A61N2005/0602 , A61N2005/0609 , A61N2005/0612 , A61N2005/0626 , A61N2005/063 , A61N2005/0659 , A61N2005/0662
Abstract: In response to local or systemic inflammation in a patient, photobiomodulation therapy is applied to a cardiac location to reduce the risk and/or occurrence of cardiac arrhythmia. Once inflammation is identified, photobiomodulation therapy can be applied in any suitable fashion (e.g., via a catheter- or transesophageal probe-mounted photoemitter, via an externally-applied photoemitter, or via photoemitter incorporated into an implantable medical device). Photobiomodulation therapy can also be employed to good advantage in conjunction with non-photobiomodulation therapy (e.g., traditional cardiac rhythm management therapies).
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10.发明申请ELECTROMAGNETIC RADIATION TARGETING DEVICES, ASSEMBLIES, SYSTEMS AND METHODS 审中-公开电磁辐射瞄准装置，装配，系统和方法公开(公告)号：US20150360048A1
公开(公告)日：2015-12-17
申请号：US14764564
申请日：2014-02-07
Applicant: ROCOMP GLOBAL, LLC
Inventor： CHARLES BRIAN ROGERS , SCOTT DAVID COMPTON
IPC: A61N5/06
CPC classification number: A61N5/0601 , A61B18/24 , A61B2018/00404 , A61B2018/20355 , A61B2018/206 , A61N5/0624 , A61N2005/0602 , A61N2005/063 , A61N2005/0632 , A61N2005/0644 , A61N2005/0664
Abstract: The present application is directed to devices, assemblies, systems and methods for targeting one or more sites with electromagnetic radiation. The devices, assemblies and systems are operationally configured to transform and convey electromagnetic radiation to one or more targeted sites. The devices, assemblies and systems may also convey one or more fluids or fluid solutions to the one or more targeted sites.
Abstract translation: 本申请涉及用于利用电磁辐射瞄准一个或多个站点的设备，组件，系统和方法。 设备，组件和系统在操作上被配置为将电磁辐射转换并传送到一个或多个目标位置。 装置，组件和系统还可以将一种或多种流体或流体溶液传送到一个或多个目标位点。
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