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52 条记录 (耗时 0.03 秒)

    Apparatus and method for selective laser-induced heating of biological tissue
    11.
    发明授权
    Apparatus and method for selective laser-induced heating of biological tissue 失效
    选择性激光诱导生物组织加热的装置和方法

    公开(公告)号：US6126655A

    公开(公告)日：2000-10-03

    申请号：US132878

    申请日：1998-08-11

    申请人： Yacov Domankevitz ,  R. Rox Anderson

    发明人： Yacov Domankevitz ,  R. Rox Anderson

    IPC分类号： A61B18/20 ,  A61B18/22 ,  A61B18/24 ,  A61B17/36

    CPC分类号： A61B18/22 ,  A61B18/20 ,  A61B18/201 ,  A61B18/24 ,  A61B2018/2272

    摘要： The invention features a probe for selectively delivering laser radiation to a first tissue having a first index of refraction relative to a second tissue having a second index of refraction less than the first index. The probe includes a laser transmitting medium having an optical axis and a tissue-contacting surface. In some embodiments, the optical axis contacts the tissue-contacting surface at an angle that is less than the critical angle for an interface between the tissue-contacting surface and the first tissue and greater than or equal to the critical angle for an interface between the tissue-contacting surface and the second tissue, wherein during operation the probe directs the laser radiation along the optical axis to the tissue-contacting surface. In other embodiments, the optical axis forms an angle with the tissue-contacting surface, and during operation the probe directs the laser radiation along the optical axis to the tissue-contacting surface, transmits a first amount of laser energy through the tissue-contacting surface when contacting the first tissue, and transmits a second amount of laser energy through the tissue-contacting surface when contacting the second tissue, wherein the angle is selected such that the first amount of laser energy is at least twice the second amount of laser energy. The invention also features related methods for selectively delivering laser radiation to tissue based on refractive index.

    摘要翻译： 本发明的特征在于一种用于选择性地将激光辐射递送到具有相对于具有小于第一指数的第二折射率的第二组织的第一折射率的第一组织的探针。 探针包括具有光轴和组织接触表面的激光传输介质。 在一些实施例中，光轴以小于组织接触表面和第一组织之间的界面的临界角度的角度接触组织接触表面，并且大于或等于临界角之间的界面 组织接触表面和第二组织，其中在操作期间，探针将沿着光轴的激光辐射引导到组织接触表面。 在其它实施例中，光轴与组织接触表面形成一角度，并且在操作期间，探针将沿着光轴的激光辐射引导到组织接触表面，将第一量的激光能量透过组织接触表面 当接触所述第一组织时，并且当接触所述第二组织时，透射所述组织接触表面的第二量的激光能量，其中所述角度被选择为使得所述第一激光能量的量是所述第二激光能量的至少两倍。 本发明还涉及基于折射率选择性地将激光辐射递送到组织的相关方法。

    Three-dimensional scanning confocal laser microscope
    12.
    发明授权
    Three-dimensional scanning confocal laser microscope 失效
    三维扫描共焦激光显微镜

    公开(公告)号：US5995283A

    公开(公告)日：1999-11-30

    申请号：US190689

    申请日：1998-11-12

    申请人： R. Rox Anderson ,  Robert H. Webb ,  Milind Rajadhyaksha

    发明人： R. Rox Anderson ,  Robert H. Webb ,  Milind Rajadhyaksha

    IPC分类号： G02B26/10 ,  G02B21/00 ,  G02B27/22 ,  G02B21/06 ,  G02B26/08

    CPC分类号： G02B21/0084 ,  G02B21/0036 ,  G02B21/0048

    摘要： A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.

    摘要翻译： 用于产生样本图像的共焦显微镜包括用于沿着第一轴扫描光束的第一扫描元件和用于沿垂直于第一轴线的第二轴以预定幅度扫描光束的第二扫描元件。 第三扫描元件沿着垂直于由第一和第二轴限定的成像平面的第三轴以预定幅度扫描光束。 第二和第三扫描元件被同步以相同的频率进行扫描。 第二和第三预定幅度是其最大振幅的百分比。 选择器确定第二和第三预定幅度，使得百分比之和等于百分之一百。

    Methods and apparatus for joining collagen-containing materials
    13.
    发明授权
    Methods and apparatus for joining collagen-containing materials 失效
    用于连接胶原蛋白的材料的方法和装置

    公开(公告)号：US5925078A

    公开(公告)日：1999-07-20

    申请号：US744518

    申请日：1996-11-04

    申请人： R. Rox Anderson

    发明人： R. Rox Anderson

    IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/20 ,  A61L24/10 ,  A61F2/54

    CPC分类号： A61B17/00491 ,  A61L24/102 ,  A61B18/00 ,  A61B18/20 ,  A61B2017/00508 ,  Y10S623/909

    摘要： A method of permanently joining a first collagen-containing material to a second collagen-containing material, each material having free ends of collagen fibrils at a surface, by bringing the free ends of collagen fibrils at the surfaces of the first and second materials into contact, heating the first and second materials for a time and to a temperature sufficient to permanently join the first and second materials at an area of contact of the free ends, wherein the temperature is above a melting temperature of the collagen fibril free ends, and below a melting temperature of intact collagen fibrils, such that collagen fibrils in the first and second materials are not denatured except at their free ends, and optionally thereafter crosslinking the collagen along the area of contact.

    摘要翻译： 通过使第一和第二材料的表面处的胶原原纤维的自由端接触，将第一含胶原材料永久性地接合到第二含胶原的材料上，每种材料在表面具有胶原原纤维的自由端 ，将第一和第二材料加热一段时间，并将其温度足以在第一和第二材料在自由端的接触区域处永久地接合，其中温度高于胶原原纤维自由端的熔融温度，并在下面 完整的胶原纤维的熔化温度，使得第一和第二种材料中的胶原原纤维在其自由端不变性，并且任选地随后沿着接触区域交联胶原蛋白。

    Hair removal using optical pulses
    16.
    发明授权
    Hair removal using optical pulses 失效
    使用光脉冲脱毛

    公开(公告)号：US5735844A

    公开(公告)日：1998-04-07

    申请号：US593565

    申请日：1996-01-30

    申请人： R. Rox Anderson ,  Melanie Grossman ,  William Farinelli

    发明人： R. Rox Anderson ,  Melanie Grossman ,  William Farinelli

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/30 ,  A61B18/00 ,  A61B18/20 ,  A61B18/22 ,  A61B19/00 ,  A61N5/06

    CPC分类号： A61B18/203 ,  A61B18/22 ,  A61B2017/00154 ,  A61B2017/00172 ,  A61B2017/22085 ,  A61B2017/306 ,  A61B2018/00023 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2090/065

    摘要： A method and apparatus for simultaneously effecting the removal of multiple hairs from a skin region by using light energy to destroy hair follicles in the region. Light energy is applied to the region through an applicator which converges the light energy to enhance destruction of desired portions of the follicles, is preferably pressed against the skin region to deform the upper layers of the skin reducing the distance from the skin surface to portions of hair follicles which are to be destroyed, including the bulge and papilla of the follicles, and which applicator is preferably cooled to minimize or eliminate thermal damage to the epidermis in the region being irradiated. Parameters for the irradiation, including pulse duration, are selected to effect complete damage of desired portions of the hair follicles in the region with minimal damage to surrounding tissue and to the patient's epidermis.

    摘要翻译： 一种用于通过使用光能来同时实现从皮肤区域去除多个毛发以破坏该区域中的毛囊的方法和装置。 光能通过会聚光能以增加卵泡所需部分的破坏的施加器施加到该区域，优选地压靠皮肤区域以使皮肤的上层变形，从而减少从皮肤表面到部分的皮肤表面的距离 要被破坏的毛囊，包括卵泡的隆起和乳头，并且哪个施用器优选被冷却以最小化或消除被照射的区域中对表皮的热损伤。 选择包括脉冲持续时间在内的照射参数，以对周围组织和患者表皮的损伤最小的区域完成对该区域毛囊期望部分的完全损伤。

    Heads for dermatology treatment
    17.
    发明授权
    Heads for dermatology treatment 有权
    头皮肤科治疗师

    公开(公告)号：US07935107B2

    公开(公告)日：2011-05-03

    申请号：US12782961

    申请日：2010-05-19

    申请人： Gregory B. Altshuler ,  R. Rox Anderson

    发明人： Gregory B. Altshuler ,  R. Rox Anderson

    IPC分类号： A61B18/18

    CPC分类号： A61B18/203 ,  A61B2018/00005 ,  A61B2018/00041 ,  A61B2018/00458 ,  A61B2018/00476 ,  A61B2090/065 ,  A61N5/0617

    摘要： Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to reduce scattering and/or other techniques for reducing the cost and/or increasing the efficacy of optical radiation for use in hair removal and other dermatological treatments. A number of embodiments are included for achieving the various objectives indicated above.

    摘要翻译： 提供了用于皮肤病学治疗的方法和装置，其涉及使用连续波（CW）辐射，治疗体积的预热，预冷，治疗期间的冷却和治疗体积后的表皮后处理冷却，各种束聚焦技术以减少 散射和/或其它降低成本和/或增加用于脱毛和其它皮肤病治疗的光辐射的功效的技术。 包括多个实施例以实现上述各种目的。