Abstract:
Methods of adjusting an intraocular lens after implantation. In some embodiments the methods include positioning an accommodating intraocular lens within an eye, the intraocular lens comprising an optic portion in fluid communication with a peripheral chamber, wherein movement of a fluid between the peripheral chamber and the optic portion in response to ciliary muscle movement changes the optical power of the lens, and reducing a power of the intraocular lens by causing the fluid to move between the optic portion and the peripheral chamber, wherein the reduction in power of the intraocular lens is not in response to ciliary muscle movement, and wherein the positioning step occurs prior to reducing the power.
Abstract:
An accommodating intraocular lens includes an optic portion, a haptic portion. The optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens responsive to forces applied to the haptic portion of the lens by contraction of the ciliary muscles and a secondary deflection mechanism. Movement of the lens element by the actuator causes the lens element to deform and the secondary deflection mechanism causes the lens to further deform.
Abstract:
The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
Abstract:
The invention generally relates to conducting an assay on a sample that isolates a bacterium from the sample, in which the assay isolates as low as about 1 CFU/ml of bacteria in the sample.
Abstract:
A fiber optic radiation transmission system is provided in which an optical fiber and a radiation source are connected to establish optical communication therebetween. Additionally, a connecting system is provided for connecting an optical fiber and a radiation source such that optical communication is established therebetween. The systems include a connector which carries the optical fiber therein. The connector is extendable within the system toward the radiation source to bring the optical fiber into optical communication with the radiation source. More particularly, the systems are configured in such a way that when the connector is extended sufficiently within the system, it seats the optical fiber relative to the radiation source under bias, thereby establishing a reliable optical connection. Once the optical connection is thus established, the connector engages a connection port associated with the radiation source to secure the system in a fully connected configuration appropriate for use. Thus, in a method of using such a system, the user simply extends the connector until the connector engages the connection port. The present invention thus provides efficient and reliable systems in which optical communication is established between an optical fiber and a radiation source.
Abstract:
The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most 24 hrs of culturing) or no culturing of the pathogen. In certain embodiments, the invention provides methods for identifying a pathogen from a sample that involve obtaining a sample including a pathogen, conducting an assay that isolates the pathogen from the sample, culturing the isolated pathogen for at most about 24 hrs, and analyzing the pathogen.
Abstract:
The invention generally relates to compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen.
Abstract:
The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
Abstract:
A method for treating benign prostatic hyperplasia using a laser is provided. The method includes emitting, in proximity to prostatic tissue, laser light at a wavelength that is controlled to be within at least one of (i) a range between about 1275 nm and about 1475 nm or (ii) a range between about 1830 nm and about 2010 nm. The wavelength is selected to have a higher absorption by water than laser light at a wavelength of 830 nm and a lower absorption by hemoglobin than laser light at the wavelength of 830 nm. Emission of the laser light is controlled such that the prostatic tissue is heated to a temperature of less than about 100° C. to coagulate the prostatic tissue.
Abstract:
Embodiments are described for a light-based dermal enhancing apparatus and methods of use. In general, the dermal enhancing apparatus includes elongated housing having opposite top and bottom ends. The housing has a translucent outer shell that defines a translucent window at the top end of the housing that is capable of permitting passage of light therethrough from one or more treatment light emitting diodes (LEDs) located in the housing. The housing may also include an inner shell that provides an interior cavity in which the interior components of the dermal enhancing apparatus are located. In addition to the treatment LEDs, a tube with a reflective lumen is located in the housing to afford a passage between the window and the LEDs. In some embodiments, the outer shell may have an elongated indicator guide that extends from the translucent window towards the bottom end of the housing so that refracted light from the light passing through the window illuminates the indicator guide.