公开(公告)号：US5512249A

公开(公告)日：1996-04-30

申请号：US336898

申请日：1994-11-10

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： A61L2/07 ,  A61L2/24 ,  F16T1/00 ,  F16K31/00

CPC分类号： F16T1/00 ,  A61L2/07 ,  A61L2/24 ,  Y10T137/4266 ,  Y10T137/7737

摘要： Apparatus for sterilizing a transfer conduit having(a) a source of steam connected to the transfer conduit,(b) a condensate conduit for draining steam condensate from the transfer conduit,(c) a valve in the condensate conduit having a valve body with an upstream portion and a downstream portion, the portions are separated by a rapidly opening flow control means, such as a diaphragm,(d) a temperature sensor in the upstream portion of the valve body, and(e) a temperature controller connected to the temperature sensor adapted to read the temperature in the upstream portion of the valve body and to open the valve when the temperature drops below a fixed set point and to close the valve when the temperature is above the fixed set point.A steam condensate drain control system and a steam condensate valve are also described and claimed.

摘要翻译： 一种用于对传输管道进行灭菌的设备，其具有（a）连接到传送管道的蒸汽源，（b）用于从传送导管排出蒸汽冷凝物的冷凝物导管，（c）冷凝物导管中的阀，其具有阀体， 上游部分和下游部分通过诸如隔膜的快速打开的流量控制装置分离，（d）阀体上游部分中的温度传感器，以及（e）温度控制器，其连接到温度 传感器适于读取阀体的上游部分中的温度，并且当温度低于固定设定点时打开阀门，并且当温度高于固定设定点时关闭阀门。 蒸汽冷凝水排放控制系统和蒸汽冷凝阀也被描述和要求保护。

公开(公告)号：US08688480B1

公开(公告)日：2014-04-01

申请号：US12799624

申请日：2010-04-28

申请人： Vijay Singh ,  C. Shane Colley ,  Paul T. Cottey ,  Logan Johnston ,  Noel Juaire ,  Akshya Kumar ,  John Sparby

发明人： Vijay Singh ,  C. Shane Colley ,  Paul T. Cottey ,  Logan Johnston ,  Noel Juaire ,  Akshya Kumar ,  John Sparby

IPC分类号： G06Q40/00 ,  G06Q10/00 ,  G06Q50/00

CPC分类号： G06Q40/08 ,  G06F19/00 ,  G06F19/328 ,  G06Q50/22

摘要： An automated system is disclosed for managing accounts receivable for outstanding healthcare accounts. In particular, the system in accordance with the present invention is an automated system which preemptively assesses the risk of denials of outstanding healthcare accounts by way of a self-learning engine driven by current data and prioritizes those accounts for follow up according to the risk profile of the account. As such, the system is able to minimize denials by the respective payers thereby improving optimizing the efforts of healthcare accounts receivable personnel while improving the revenue yield and minimizing the revenue cycle.

摘要翻译： 披露了一个自动化系统来管理优秀医疗账户的应收账款。 特别地，根据本发明的系统是一种自动化系统，其通过根据当前数据驱动的自学习引擎来先发性地评估拒绝未完成的医疗保健账户的风险，并且根据风险简档来优先考虑这些账户的后续跟踪 的帐户。 因此，该系统能够最大限度地减少相应付款人的否认，从而改善医疗保健应收账款人员的努力，同时提高收入收益并最大限度地减少收入周期。

公开(公告)号：US08621781B2

公开(公告)日：2014-01-07

申请号：US13246335

申请日：2011-09-27

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： A01G31/02

CPC分类号： A01G31/02 ,  Y02P60/216

摘要： A low cost valve and system for automated ebb and flow irrigation utilizes a collapsible sleeve to control fluid flow direction. No external power, moving parts, or floats are needed to operate the valve, resulting in improved reliability, low operating cost, and minimal need for maintenance. The valve operates using feed pressure to close the drain when hydroponic nutrient solution is pumped into the cultivation chamber. The valve drains automatically once the pump is stopped, usually by means of a timer, and the spent hydroponic solution is recovered. The fill/drain cycle is repeated as needed to keep the plants moist, yet not waterlogged.

摘要翻译： 低成本的阀门和自动化潮流灌溉系统利用可折叠套管来控制流体流动方向。 不需要外部电源，移动部件或浮子来操作阀门，从而提高了可靠性，降低了运行成本，并且维护费用也很少。 当水培营养液被泵入培养室时，阀门使用进料压力关闭排水管。 一旦泵停止，阀门就会自动排水，通常通过定时器排出，并回收废水溶液。 根据需要重复填充/排出循环，以保持植物潮湿，但不会淹水。

公开(公告)号：US20110006878A1

公开(公告)日：2011-01-13

申请号：US12921459

申请日：2008-08-20

申请人： Manuel Nyffeler ,  Radislav A. Potyrailo ,  Vincent F. Pizzi ,  William G. Morris ,  Gerard J. Gach ,  Vijay Singh

发明人： Manuel Nyffeler ,  Radislav A. Potyrailo ,  Vincent F. Pizzi ,  William G. Morris ,  Gerard J. Gach ,  Vijay Singh

IPC分类号： G06F7/04

CPC分类号： G06K19/0723 ,  C12M41/48 ,  G06Q20/3278 ,  G06Q20/409 ,  G11C11/22

摘要： This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written into the memory chip, so that the information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.

摘要翻译： 本发明提供一种系统和装置，其能够认证并防止一次性生物处理部件的非法制造和未经授权的操作。 本发明利用铁电随机存取存储器（FRAM）芯片来存储附着在一次性生物处理部件上的RFID标签上的错误纠正信息，其中将错误纠正信息写入存储器芯片，使得信息可以保持 当RFID标签和一次性生物处理组件被伽马灭菌时在芯片中。 此外，本发明还包括一种用于认证一次性生物过程组件的方法，其减少责任，因为在硬件上不使用假劣质的一次性部件，因此用户不会提出不合理的投诉。

公开(公告)号：US20100068336A1

公开(公告)日：2010-03-18

申请号：US12466250

申请日：2009-05-14

申请人： Vijay Singh ,  James E. Pettigrew ,  Carl M. Parsons ,  George C. Fahey

发明人： Vijay Singh ,  James E. Pettigrew ,  Carl M. Parsons ,  George C. Fahey

IPC分类号： A23L1/20 ,  A23K1/00 ,  A23K1/18 ,  A23J1/14 ,  A23J3/30 ,  A23J3/32 ,  A23J3/34 ,  B02C11/08

CPC分类号： A23K10/30 ,  A23L11/07

摘要： Methods and systems for processing oilseed meal. Oilseed meal is hydrated to provide a hydrated oilseed meal. A particle size of the hydrated oilseed meal is reduced to provide a size-reduced oilseed meal. Enhanced oilseed meal is physically separated from the size-reduced oilseed meal.

摘要翻译： 油籽粉加工方法与系统 油籽粉水合，提供水合油籽粉。 减少水合油籽粉的粒度以提供尺寸减小的油籽粉。 增强的油籽粉与大小减少的油籽粉物理分离。

公开(公告)号：US20070195642A1

公开(公告)日：2007-08-23

申请号：US11702754

申请日：2007-02-06

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： B01F11/00

CPC分类号： B01F11/0017 ,  B01F15/00824 ,  B01F15/0085 ,  B01F15/00915

摘要： A method and apparatus is provided for non-invasively mixing ingredients in closed containers. Mixing is performed by inducing waves in the liquid to be mixed. This is achieved by rocking the container in precise phase so as to produce resonance. With the waves moving back and forth in resonance, it is possible to mix with very low energy requirements compared to prior art. Mixing ingredients with resonant waves in a closed container eliminates the need for an invasive mixer and has obvious advantages in minimizing contamination. This makes the device ideal for biological processing that typically require sterile operation.

摘要翻译： 提供了一种用于在密闭容器中非侵入性地混合成分的方法和装置。 通过在待混合的液体中引起波而进行混合。 这是通过以精确的相位摆动容器来实现的，以便产生共振。 随着波浪在谐振中来回移动，与现有技术相比，可以以非常低的能量需求进行混合。 在密闭容器中将共振波混合成分消除了对侵入式混合器的需要，并且在污染最小化方面具有明显的优势。 这使得该装置成为通常需要无菌操作的生物处理的理想选择。

公开(公告)号：US07195394B2

公开(公告)日：2007-03-27

申请号：US10787656

申请日：2004-07-19

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： B01F11/00

CPC分类号： B01F11/0017 ,  B01F15/00824 ,  B01F15/0085 ,  B01F15/00915

摘要： A method and apparatus is provided for non-invasively mixing ingredients in closed containers. Mixing is performed by inducing waves in the liquid to be mixed. This is achieved by rocking the container in precise phase so as to produce resonance. With the waves moving back and forth in resonance, it is possible to mix with very low energy requirements compared to prior art. Mixing ingredients with resonant waves in a closed container eliminates the need for an invasive mixer and has obvious advantages in minimizing contamination. This makes the device ideal for biological processing that typically require sterile operation.

摘要翻译： 提供了一种用于在密闭容器中非侵入性地混合成分的方法和装置。 通过在待混合的液体中引起波而进行混合。 这是通过以精确的相位摆动容器来实现的，以便产生共振。 随着波浪在谐振中来回移动，与现有技术相比，可以以非常低的能量需求进行混合。 在密闭容器中将共振波混合成分消除了对侵入式混合器的需要，并且在污染最小化方面具有明显的优势。 这使得该装置成为通常需要无菌操作的生物处理的理想选择。

公开(公告)号：US06544788B2

公开(公告)日：2003-04-08

申请号：US09784568

申请日：2001-02-15

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： C12N500

CPC分类号： C12M23/14 ,  B01F11/0017 ,  C12M27/16 ,  C12M29/10 ,  C12M33/14 ,  Y10S435/818

摘要： A disposable bioreactor for perfusion cell culture. Cells are grown in a plastic bag that is rocked and aerated on a mechanical platform. The bioreactor bag contains a filter that allows liquid to be removed from the bioreactor-without losing cells. Nutrients may be added through another port. The perfusion filter is constructed such that it can move freely on the liquid surface. The filter is flicked rapidly across the surface as a result of the rocking motion of the bioreactor and this tangential motion of the filter keeps it from clogging. A weight-based control system regulates feed and harvest rates and allows weeks of continuous operation. This invention has numerous applications in biotechnology and medicine.

摘要翻译： 用于灌注细胞培养的一次性生物反应器。 细胞在塑料袋中生长，该塑料袋在机械平台上摇动并充气。 生物反应器袋包含允许从生物反应器中除去液体而不损失细胞的过滤器。 营养素可以通过另一个港口加入。 灌注过滤器被构造成使得其可以在液体表面上自由移动。 过滤器由于生物反应器的摇摆运动而快速地飞过表面，并且过滤器的这种切向运动使其不被堵塞。 基于重量的控制系统调节饲料和收获率，并允许持续数周的操作。 本发明在生物技术和医药方面有许多应用。

公开(公告)号：US06190913B1

公开(公告)日：2001-02-20

申请号：US09138590

申请日：1998-08-22

申请人： Vijay Singh

发明人： Vijay Singh

IPC分类号： C12N502

CPC分类号： C12M35/04 ,  B01F11/0017 ,  C12M23/14 ,  C12M23/56 ,  C12M27/16

摘要： The present invention provides a novel apparatus for culturing animal, insect, microbial, or plant cells whereby an inflated plastic bag provides a sterile, disposable cultivation chamber. The inflated bag is partially filled with liquid cultivation media and cells, and placed on rocking mechanism that moves the bag to and fro thereby inducing a wave-like motion to the liquid contained therein. This motion ensures cell suspension, bulk mixing, and oxygen transfer from the liquid surface to the respiring cells without damaging shear forces or foam generation. Air is passed through the bag to provide oxygen, and sweep out evolved carbon dioxide.

摘要翻译： 本发明提供了一种用于培养动物，昆虫，微生物或植物细胞的新型装置，由此充气的塑料袋提供无菌的一次性培养室。 充气袋部分地填充有液体培养基和细胞，并且放置在摇动机构上，使得袋子来回移动，从而对其中所含的液体引起波浪状运动。 该运动确保细胞悬浮，本体混合和从液体表面到呼吸细胞的氧传递，而不损害剪切力或发泡。 空气通过袋子提供氧气，并吹扫出二氧化碳。

公开(公告)号：US09428482B2

公开(公告)日：2016-08-30

申请号：US13981279

申请日：2012-01-24

申请人： Sundeep Dugar ,  Dinesh Mahajan ,  Peter Giannousis Pantelis ,  Vijay Singh ,  Kamal Kishore Kapoor

发明人： Sundeep Dugar ,  Dinesh Mahajan ,  Peter Giannousis Pantelis ,  Vijay Singh ,  Kamal Kishore Kapoor

IPC分类号： C07D311/74 ,  C07D311/30

CPC分类号： C07D311/74 ,  C07D311/30

摘要： The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives. A principle objective of the disclosure is to provide a new and useful method of synthesis to obtain polyphenols in isomerically pure and/or racemic forms.

摘要翻译： 本发明提供用于制备外消旋和/或光学纯的表儿茶素，表没食子儿茶素和相关多酚本身或其各种官能化衍生物的合成方法。 本公开的主要目的是提供一种新的有用的合成方法以获得异构纯和/或外消旋形式的多酚。