Method and system for monitoring intracranial pressure
    11.
    发明授权
    Method and system for monitoring intracranial pressure 有权
    监测颅内压的方法和系统

    公开(公告)号:US08696593B2

    公开(公告)日:2014-04-15

    申请号:US11528218

    申请日:2006-09-27

    IPC分类号: A61B5/00

    摘要: Embodiments of the present invention relate to a system and method for monitoring intracranial pressure. Embodiments of the present invention include emitting an electromagnetic wavelength into forehead tissue of a patient and detecting characteristics of the electromagnetic wavelength after the electromagnetic wavelength has been scattered by the tissue. The characteristics may include variations in the electromagnetic wavelength corresponding to a pulse. Further, embodiments of the present invention include analyzing the variations to identify venous pulsations, and determining whether intracranial pressure is elevated in the patient based on a correlation between the venous pulsations and levels of intracranial pressure.

    摘要翻译: 本发明的实施例涉及一种用于监测颅内压的系统和方法。 本发明的实施例包括将电磁波长发射到患者的前额组织中,并且在电磁波长被组织散射之后检测电磁波长的特性。 特征可以包括对应于脉冲的电磁波长的变化。 此外,本发明的实施例包括分析变异以识别静脉脉动,并且基于静脉脉动与颅内压水平之间的相关性来确定患者中颅内压是否升高。

    SYSTEM AND SENSOR FOR EARLY DETECTION OF SHOCK OR PERFUSION FAILURE AND TECHNIQUE FOR USING THE SAME
    12.
    发明申请
    SYSTEM AND SENSOR FOR EARLY DETECTION OF SHOCK OR PERFUSION FAILURE AND TECHNIQUE FOR USING THE SAME 失效
    用于早期检测震动或灌注失败的系统和传感器及其使用技术

    公开(公告)号:US20090171237A1

    公开(公告)日:2009-07-02

    申请号:US12338797

    申请日:2008-12-18

    IPC分类号: A61B5/053

    摘要: According to various embodiments, a system, method, and sensor are provided that is capable of monitoring electrical impedance of oral or nasal mucosal tissue. Such sensors may be appropriate for assessing gut hypoperfusion, gut ischemia, or the onset of shock. The electrical impedance of the oral mucosa or other tissues in the upper respiratory tract may be used to non-invasively assess the clinical state of gastrointestinal tissue.

    摘要翻译: 根据各种实施例,提供能够监测口腔或鼻粘膜组织的电阻抗的系统,方法和传感器。 这样的传感器可能适用于评估肠灌注不足,肠缺血或休克的发作。 上呼吸道口腔粘膜或其他组织的电阻抗可用于非侵入性地评估胃肠组织的临床状态。

    Method and system for monitoring intracranial pressure
    14.
    发明申请
    Method and system for monitoring intracranial pressure 有权
    监测颅内压的方法和系统

    公开(公告)号:US20080077023A1

    公开(公告)日:2008-03-27

    申请号:US11528218

    申请日:2006-09-27

    IPC分类号: A61B5/02

    摘要: Embodiments of the present invention relate to a system and method for monitoring intracranial pressure. Embodiments of the present invention include emitting an electromagnetic wavelength into forehead tissue of a patient and detecting characteristics of the electromagnetic wavelength after the electromagnetic wavelength has been scattered by the tissue. The characteristics may include variations in the electromagnetic wavelength corresponding to a pulse. Further, embodiments of the present invention include analyzing the variations to identify venous pulsations, and determining whether intracranial pressure is elevated in the patient based on a correlation between the venous pulsations and levels of intracranial pressure.

    摘要翻译: 本发明的实施例涉及一种用于监测颅内压的系统和方法。 本发明的实施例包括将电磁波长发射到患者的前额组织中,并且在电磁波长被组织散射之后检测电磁波长的特性。 特征可以包括对应于脉冲的电磁波长的变化。 此外,本发明的实施例包括分析变异以识别静脉脉动,并且基于静脉脉动与颅内压水平之间的相关性来确定患者中颅内压是否升高。

    DYNAMIC ADJUSTMENT OF TUBE COMPENSATION FACTOR BASED ON INTERNAL CHANGES IN BREATHING TUBE
    15.
    发明申请
    DYNAMIC ADJUSTMENT OF TUBE COMPENSATION FACTOR BASED ON INTERNAL CHANGES IN BREATHING TUBE 审中-公开
    基于呼吸管内部变化的管补偿因子的动态调整

    公开(公告)号:US20100288283A1

    公开(公告)日:2010-11-18

    申请号:US12467113

    申请日:2009-05-15

    IPC分类号: A61M16/04

    摘要: This disclosure describes systems and methods for adjusting a determination of the amount of breathing assistance a patient requires while on a ventilator. In general, in determining the amount of breathing assistance required, the ventilator takes into account an airflow resistance attributable to the tube used to deliver ventilation to the patient's lungs. A tube compensation factor is calculated using a tube compensation algorithm, or similar equation. In particular, the tube compensation factor represents the resistance to airflow attributable to the breathing tube itself based on, inter alia, frictional drag, turbulence, and an internal diameter of the tube. Changes in the tube during ventilation impact the calculation of the breathing assistance required by the patient and are accounted for when compensating for the breathing tube.

    摘要翻译: 本公开描述了用于在通气机上调整患者呼吸辅助量的确定的系统和方法。 通常,在确定所需的呼吸辅助量时,呼吸机考虑到归因于用于向患者的肺部传递通气的管的气流阻力。 使用管补偿算法或类似方程计算管补偿系数。 特别地,管补偿系数表示基于呼吸管本身的气流阻力,尤其是基于摩擦阻力,湍流和管的内径。 通气期间管中的变化影响患者所需呼吸辅助的计算,并在补偿呼吸管时予以考虑。

    System and methods for optical sensing and drug delivery using microneedles
    16.
    发明申请
    System and methods for optical sensing and drug delivery using microneedles 失效
    使用微针的光学感应和药物输送的系统和方法

    公开(公告)号:US20080221408A1

    公开(公告)日:2008-09-11

    申请号:US11716145

    申请日:2007-03-09

    IPC分类号: A61M37/00

    摘要: The current techniques provide a system for monitoring a physiological parameter of a patient using microneedles that are coupled to an optical system, allowing spectroscopic measurements to be made immediately below the outer layer of the epidermis. In embodiments of the present invention, the results of the spectroscopic measurements are used to control the administration of a drug through an intravenous tube. In other embodiments, the microneedles may be coated with a drug for administration to the patient. In other embodiments, the microneedles may be mounted in a probe, wherein an actuator is used to move the needles into contact with the skin, and a drug delivery system is used to infuse the drug into the patient. A method for making needles is also provided.

    摘要翻译: 目前的技术提供了一种用于使用耦合到光学系统的微针来监测患者的生理参数的系统,允许在表皮的外层的正下方进行光谱测量。 在本发明的实施方案中,光谱测量的结果用于通过静脉内管来控制药物的给药。 在其它实施方案中,可以用用于给患者给药的药物涂覆微针。 在其他实施例中,微针可以安装在探针中,其中致动器用于将针移动到与皮肤接触,并且药物递送系统用于将药物注入患者体内。 还提供了制造针的方法。

    Endotracheal cuff and technique for using the same
    17.
    发明申请
    Endotracheal cuff and technique for using the same 审中-公开
    气管内袖口及使用技巧

    公开(公告)号:US20070289596A1

    公开(公告)日:2007-12-20

    申请号:US11453161

    申请日:2006-06-14

    IPC分类号: A62B9/06 A61M16/00

    摘要: An inflatable balloon cuff may be adapted to seal a patient's trachea via a mucoadhesive coating when associated with an endotracheal tube. The mucoadhesive seal may enhance a cuffs mechanical pressure seal, or may be used to seal the trachea at very low cuff inflation pressures. Also provided are inflatable balloon cuffs that include agents that may promote tracheal tissue growth and/or regeneration.

    摘要翻译: 充气气囊可以适合于当与气管内导管相关联时通过粘膜粘附剂包封密封患者的气管。 粘膜粘附密封可以增强袖带机械压力密封,或者可以用于在非常低的袖带充气压力下密封气管。 还提供了包括可促进气管组织生长和/或再生的药剂的可充气气囊。

    Hydrogel thin film for use as a biosensor
    20.
    发明授权
    Hydrogel thin film for use as a biosensor 有权
    水凝胶薄膜用作生物传感器

    公开(公告)号:US08092993B2

    公开(公告)日:2012-01-10

    申请号:US12338806

    申请日:2008-12-18

    IPC分类号: C12Q1/68 G01N33/53

    摘要: The present disclosure provides a biosensor capable of producing an indicator response upon detection of the presence of certain metabolites in a biological sample. The biosensor includes a hydrogel that is functionalized with affinity molecules specific to markers for one or more pathogens. The biosensor also includes a detection system adapted to detect the binding the pathogen-specific markers with their corresponding affinity molecules.

    摘要翻译: 本公开提供了一种生物传感器,其能够在检测到生物样品中某些代谢物的存在时产生指示剂反应。 生物传感器包括水凝胶,该水凝胶用一种或多种病原体的标记特异的亲和分子官能化。 生物传感器还包括适于检测病原体特异性标记物与其相应的亲和分子的结合的检测系统。