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    UNIVERSAL VALVE ANNULUS SIZING DEVICE
    11.
    发明申请
    UNIVERSAL VALVE ANNULUS SIZING DEVICE 审中-公开
    通用阀门尺寸设备

    公开(公告)号：US20140207011A1

    公开(公告)日：2014-07-24

    申请号：US14222598

    申请日：2014-03-22

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Giovanni Righini ,  Felice Giuseppe Carlino ,  Giovanni Rolando

    IPC: A61B5/107 ,  A61B5/02

    CPC classification number: A61F2/2496 ,  A61B5/02 ,  A61B5/103 ,  A61B5/1076 ,  A61B5/6871

    Abstract: A device for measuring an internal dimension of a native cardiac valve annulus includes an elongated support member having a proximal portion and a distal portion. A measuring portion is coupled to the distal portion, and an indicator is coupled to the proximal portion of the support member. The measuring portion is biased towards a deployed configuration such that when deployed it applies an outwardly directed radial force to the native valve annulus.

    Abstract translation: 用于测量天然心脏瓣膜环的内部尺寸的装置包括具有近端部分和远端部分的细长支撑构件。 测量部分联接到远端部分，并且指示器联接到支撑构件的近端部分。 测量部分被朝向展开构型偏置，使得当其展开时，其将向外指向的径向力施加到自然瓣膜环。

    SUPPORT DEVICE FOR HEART VALVE PROSTHESES
    12.
    发明申请
    SUPPORT DEVICE FOR HEART VALVE PROSTHESES 有权
    用于心脏瓣膜的支持装置

    公开(公告)号：US20130268068A1

    公开(公告)日：2013-10-10

    申请号：US13835593

    申请日：2013-03-15

    Applicant: SORIN GROUP ITALIA S.R.L.

    Inventor： Andrea Marchisio ,  Giovanni Rolando ,  Paolo Gaschino

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2427

    Abstract: A support device for implanting a stentless heart valve prosthesis having three leaflets adapted for coapting and defining three corresponding commissures is disclosed. The support device includes a shaft defining a manipulation axis, the shaft having a proximal portion and a distal portion, and three support formations integrally formed and extending from the proximal end of the shaft, the support formations angularly distributed about the manipulation axis of the shaft, such that each of the support formations correspond to locations of each of the commissures of the stentless heart valve prosthesis. The shaft includes a connection portion flexibly connecting the shaft and the support formations to permit a displacement of the manipulation axis with respect to the support formations. The shaft, the plurality of support formations and the connection portion are integrally formed from a single tubular element.

    Abstract translation: 公开了一种用于植入无支架心脏瓣膜假体的支撑装置，其具有三个适用于起皱和限定三个相应连合的小叶。 所述支撑装置包括限定操作轴的轴，所述轴具有近端部分和远端部分，以及从所述轴的近端一体地形成并延伸的三个支撑结构，所述支撑结构围绕所述轴的操纵轴线成角度地分布 ，使得每个支撑结构对应于无支架式心脏瓣膜假体的每个连合的位置。 轴包括连接部分，该连接部分柔性地连接轴和支撑结构，以允许操纵轴相对于支撑结构的位移。 轴，多个支撑结构和连接部分由单个管状元件整体形成。

    METHOD FOR PREPARING BIOLOGICAL TISSUES FOR USE IN BIOLOGICAL PROSTHESES
    16.
    发明申请
    METHOD FOR PREPARING BIOLOGICAL TISSUES FOR USE IN BIOLOGICAL PROSTHESES 有权
    制备生物组织用于生物学前景的方法

    公开(公告)号：US20160095957A1

    公开(公告)日：2016-04-07

    申请号：US14966675

    申请日：2015-12-11

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Marina Strasly ,  Giovanni Rolando

    IPC: A61L27/36

    CPC classification number: A61L27/3687 ,  A61K35/12 ,  A61L27/3683

    Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.

    Abstract translation: 用于生物假体处理生物组织的方法包括通过包含戊二醛的固定溶液固定生物组织并通过用解毒溶液处理来固定固定的生物组织的步骤。 解毒步骤包括通过用消除溶液处理和用解毒溶液处理来消除磷脂的一种或两种。 消除溶液包括1,2-辛二醇和乙醇。 解毒溶液包括牛磺酸或高半胱氨酸。

    Valve prosthesis and kit
    17.
    发明授权
    Valve prosthesis and kit 有权
    阀门假体和试剂盒

    公开(公告)号：US09186249B2

    公开(公告)日：2015-11-17

    申请号：US13962789

    申请日：2013-08-08

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Laura Ghione ,  Andrea Marchisio ,  Monica Achiluzzi

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075

    Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.

    Abstract translation: 描述了一种阀门假体，其包括：环形结构，以及多个瓣叶，以及围绕环形结构附接的多个锚固构件，所述锚定构件包括：腹板部分，其联接到所述环形结构并且轴向延伸， 所述端部具有用于插入所述假体的插入状态，其中所述端部与所述腹板部分对准并且相对于所述环形结构轴向延伸; 以及用于锚定假体的锚固条件，其中端部部分以与环形结构的径向外侧的腹板部分成一定角度延伸，以分别使瓣膜近端和远端锚固假体，并且其中一个端部形成 与网部分呈钝角。

    VALVE PROSTHESIS AND KIT
    18.
    发明申请
    VALVE PROSTHESIS AND KIT 有权
    阀门检查和工具包

    公开(公告)号：US20140046434A1

    公开(公告)日：2014-02-13

    申请号：US13962789

    申请日：2013-08-08

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Laura Ghione ,  Andrea Marchisio ,  Monica Achiluzzi

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075

    Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.

    Abstract translation: 描述了一种阀门假体，其包括：环形结构，以及多个瓣叶，以及围绕环形结构附接的多个锚固构件，所述锚定构件包括：腹板部分，其联接到所述环形结构并且轴向延伸， 所述端部具有用于插入所述假体的插入状态，其中所述端部与所述腹板部分对准并且相对于所述环形结构轴向延伸; 以及用于锚定假体的锚固条件，其中端部部分以与环形结构的径向外侧的腹板部分成一定角度延伸，以分别使瓣膜近端和远端锚固假体，并且其中一个端部形成 与网部分呈钝角。

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