公开(公告)号：US20180271593A1

公开(公告)日：2018-09-27

申请号：US15923489

申请日：2018-03-16

Applicant: St. Jude Medical, Atrial Fibrillation Division, Inc.

Inventor： Saurav Paul ,  Harry A. Puryear ,  Riki Chou Thao ,  Hong Cao

IPC: A61B18/14 ,  A61B18/00 ,  A61B18/12

CPC classification number: A61B18/1492 ,  A61B18/1206 ,  A61B2018/00023 ,  A61B2018/00577 ,  A61B2018/00875

Abstract: The present invention is directed to bipolar ablation systems. A bipolar electrode system for ablation therapy is disclosed, including a pressure-sensitive conducting composite layer and a pair of electrodes in electrical conductive contact or communication with the pressure-sensitive conducting composite layer. Energy (e.g., ablation energy) is delivered via the pressure-sensitive conductive composition when sufficient pressure is applied to transform the pressure-sensitive conductive composite to an electrical conductor. An electrically insulative flexible layer, which may include a passageway for a fill material is also disclosed. In some embodiments, the systems can also be used for targeted delivery of compounds, such as drugs, using a bipolar electrode.

公开(公告)号：US20170360448A1

公开(公告)日：2017-12-21

申请号：US15634904

申请日：2017-06-27

Applicant: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.

Inventor： James V. Kauphusman ,  Andre d'Avila ,  Vivek Reddy ,  William M. Sutton ,  Steven C. Christian ,  Harry A. Puryear

IPC: A61B17/12 ,  A61B18/14 ,  A61B18/00

CPC classification number: A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12122 ,  A61B17/12136 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00285 ,  A61B2018/00577 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821

Abstract: A method is provided for ablating a portion of the myocardium. The method includes inserting an occlusion catheter into a vessel on a heart, occluding the vessel using the occlusion catheter, inserting an ablation catheter into a chamber of the heart, positioning the ablation catheter against the myocardium, and ablating a portion of the myocardium while the vessel is occluded. The system includes an occlusion catheter having a catheter body including a tubular member having a distal portion and a bend located in the distal portion, a balloon located proximal of the bend and configured to contact an inner surface of the CS when positioned therewithin, a plurality of marker bands positioned on the catheter body, and a plurality of electrodes positioned on the catheter body. One or more electrodes or coils can be used as a reference for an electroanatomical system and can be disposed on the occlusion catheter.

公开(公告)号：US09610119B2

公开(公告)日：2017-04-04

申请号：US14087991

申请日：2013-11-22

Applicant: St. Jude Medical, Atrial Fibrillation Division, Inc.

Inventor： Jeffrey M. Fish ,  Israel A. Byrd ,  Lynn E. Clark ,  Jeremy D. Dando ,  Christopher J. Geurkink ,  Harry A. Puryear ,  Saurav Paul

IPC: A61B18/10 ,  A61B18/14 ,  A61B5/00 ,  A61B5/01 ,  A61B5/053 ,  A61B5/107 ,  A61B5/0402 ,  A61B5/042 ,  A61B18/12 ,  A61B18/00 ,  A61B18/02 ,  A61B34/30 ,  A61B90/00

CPC classification number: A61B18/1492 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/0538 ,  A61B5/1076 ,  A61B5/1079 ,  A61B5/4836 ,  A61B5/742 ,  A61B18/1233 ,  A61B18/14 ,  A61B2018/00178 ,  A61B2018/00351 ,  A61B2018/00714 ,  A61B2018/00738 ,  A61B2018/00779 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61B2034/301 ,  A61B2090/065 ,  A61B2218/002

Abstract: A method and system for assessing lesion formation in tissue is provided. The system includes an electronic control unit (ECU) configured to acquire magnitudes for a component of a complex impedance between an electrode and tissue, and the power applied to the tissue during lesion formation. The ECU is configured to calculate a value responsive to the complex impedance component and the power. The value is indicative of a predicted lesion depth, a likelihood the lesion has reached a predetermined depth, or a predicted tissue temperature. The method includes acquiring magnitudes for a component of a complex impedance between an electrode and tissue and the power applied during lesion formation. The method includes calculating a value responsive to the complex impedance component and the power, the value being indicative of a predicted lesion depth, a likelihood the lesion has reached a predetermined depth, and/or a predicted tissue temperature.

公开(公告)号：US20160256682A1

公开(公告)日：2016-09-08

申请号：US15064664

申请日：2016-03-09

Applicant: St. Jude Medical, Atrial Fibrillation Division, Inc.

Inventor： Saurav Paul ,  Troy T. Tegg ,  Israel A. Byrd ,  Riki Thao ,  Harry A. Puryear ,  Linda Nemec ,  John M. Berns

IPC: A61N1/32 ,  A61B18/14

Abstract: Catheter systems include direction-sensitive, multi-polar tip electrode assemblies for electroporation-mediated therapy, electroporation-induced primary necrosis therapy and electric field-induced apoptosis therapy, including configurations for producing narrow, linear lesions as well as distributed, wide area lesions. A monitoring system for electroporation therapy includes a mechanism for delivering electrochromic dyes to a tissue site as well as a fiber optic arrangement to optically monitor the progress of the therapy as well as to confirm success post-therapy. A fiber optic temperature sensing electrode catheter includes a tip electrode having a cavity whose inner surface is impregnated or coated with thermochromic/thermotropic material that changes color with changes in temperature. An optic fiber/detector arrangement monitors the thermochromic or thermotropic materials, acquiring a light signal and generating an output signal indicative of the spectrum of the light signal. An analyzer determines an electrode temperature based on the detector output and predetermined spectrum versus temperature calibration data.

Abstract translation: 导管系统包括用于电穿孔介导治疗的方向敏感的多极尖端电极组件，电穿孔诱导的原发性坏死治疗和电场诱导的凋亡治疗，包括用于产生狭窄的线性损伤以及分布的广泛区域损伤的构造。 用于电穿孔治疗的监测系统包括将电致变色染料递送到组织部位的机制以及光学配置以光学监测治疗进展以及确认疗法后的成功。 光纤温度感测电极导管包括具有腔体的尖端电极，其内表面被浸渍或涂覆有随着温度变化而改变颜色的热变色/热致变色材料。 光纤/检测器装置监测热致变色或热致变色材料，获取光信号并产生指示光信号光谱的输出信号。 分析仪基于检测器输出和预定的频谱对温度校准数据来确定电极温度。