公开(公告)号：US20130252261A1

公开(公告)日：2013-09-26

申请号：US13849056

申请日：2013-03-22

Applicant: SURMODICS, INC.

Inventor： Gary Opperman ,  Wendy Nelson

IPC: G01N21/78

CPC classification number: G01N33/581 ,  C12Q1/28 ,  G01N21/78 ,  G01N33/52 ,  G01N33/535 ,  G01N33/558

Abstract: The invention provides compositions, kits, and methods for performing colorimetric analysis. A substrate is reacted to generate a chromogenic reaction product, and a reaction stop reagent that is a sulfonic acid is added to stop and stabilize the reaction product. The absorbance properties of the chromogenic reaction product can be maintained over significantly longer periods of time of that of conventional reagents and methods. The sulfonic acid can be used in assays such as ELISAs in order to provide a more accurate and safer detection of analytes in a biological sample.

Abstract translation: 本发明提供用于进行比色分析的组合物，试剂盒和方法。 使底物反应生成显色反应产物，并加入作为磺酸的反应停止试剂以停止并稳定反应产物。 显色反应产物的吸光度特性可以在常规试剂和方法的显着更长的时间内保持。 磺酸可用于诸如ELISA的测定中，以便提供对生物样品中分析物的更准确和更安全的检测。

公开(公告)号：US11576774B2

公开(公告)日：2023-02-14

申请号：US16914950

申请日：2020-06-29

Applicant: Surmodics, Inc.

Inventor： Bruce M. Jelle ,  Joram Slager ,  Joseph S. McGonigle ,  Rick Murphy ,  Andrew G. Bach ,  Teryl L. Woodwick Sides ,  Ambereen Angamuthu ,  Sean Lundquist ,  Gary Opperman ,  Nathan A. Lockwood

IPC: A61F2/24 ,  A61M25/10 ,  A61M25/01 ,  A61M25/06 ,  A61M25/09

Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.

公开(公告)号：US20210015613A1

公开(公告)日：2021-01-21

申请号：US16914950

申请日：2020-06-29

Applicant: Surmodics, Inc.

Inventor： Bruce M. Jelle ,  Joram Slager ,  Joseph S. McGonigle ,  Rick Murphy ,  Andrew G. Bach ,  Teryl L. Woodwick Sides ,  Ambereen Angamuthu ,  Sean Lundquist ,  Gary Opperman ,  Nathan A. Lockwood

IPC: A61F2/24 ,  A61M25/10

Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.

公开(公告)号：US20170367824A1

公开(公告)日：2017-12-28

申请号：US15543704

申请日：2016-01-14

Applicant: SURMODICS, INC.

Inventor： Bruce M. Jelle ,  Joram Slager ,  Joseph S. McGonigle ,  Rick Murphy ,  Andrew G. Bach ,  Teryl L. Woodwick Sides ,  Ambereen Angamuthu ,  Sean Lundquist ,  Gary Opperman ,  Nathan A. Lockwood

IPC: A61F2/24 ,  A61M25/01 ,  A61M25/09 ,  A61M25/10

CPC classification number: A61F2/2433 ,  A61M25/0102 ,  A61M25/0668 ,  A61M25/09041 ,  A61M25/10 ,  A61M2025/0681 ,  A61M2025/1081

Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.

公开(公告)号：US08632877B2

公开(公告)日：2014-01-21

申请号：US13632936

申请日：2012-10-01

Applicant: Surmodics, Inc.

Inventor： Gary Opperman

IPC: B32B27/32 ,  B32B3/26 ,  B32B27/34 ,  B32B27/00

CPC classification number: A61L29/085 ,  A61L27/34 ,  A61L31/10 ,  A61L2420/02 ,  B01D67/0088 ,  B01D67/0093 ,  B01D71/36 ,  B01D2323/02 ,  B01D2323/345 ,  B01D2323/38 ,  B01D2325/04 ,  B05D1/18 ,  B05D3/061 ,  B05D7/02 ,  B82Y30/00 ,  Y10T428/24322 ,  Y10T428/249953 ,  Y10T428/26 ,  Y10T428/265 ,  Y10T428/31725 ,  Y10T428/31855

Abstract: The invention provides methods for forming ultra-thin hydrophilic polymeric coatings on articles, as well as articles formed therefrom. The coatings are formed by irradiating a composition including a polymer having pendent photoreactive groups while the composition is in contact with a surface of the article.

Abstract translation: 本发明提供了在物品上形成超薄亲水性聚合物涂层以及由其形成的制品的方法。 通过在组合物与制品的表面接触的同时照射包含具有侧基光反应性基团的聚合物的组合物来形成涂层。