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公开(公告)号:US20180214643A1
公开(公告)日:2018-08-02
申请号:US15933082
申请日:2018-03-22
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall SMITH
CPC classification number: A61M11/005 , A61M11/001 , A61M2205/33 , A61M2205/3317 , B05B12/004 , B05B12/081 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , G01N29/22 , G01N29/42 , G06F19/3456 , G16H20/13
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US11998678B2
公开(公告)日:2024-06-04
申请号:US17194369
申请日:2021-03-08
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
CPC classification number: A61M11/00 , A61M11/005 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , A61M2205/3317 , A61M2205/3386 , A61M2205/50 , A61M2205/583 , B05B12/081 , B06B2201/77
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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公开(公告)号:US11839891B2
公开(公告)日:2023-12-12
申请号:US16621604
申请日:2018-08-23
Applicant: STAMFORD DEVICES LIMITED
Inventor: Joseph Grehan , Noel Coyle , Russell Greaney , Stephen Thornton
CPC classification number: B05B12/081 , A61M11/005 , A61M15/0085 , B05B17/0646 , B05B17/0669 , A61M2205/3317 , A61M2205/50
Abstract: An aerosol delivery system has an aerosol generator with a vibrating aperture plate (10) and an actuator (11, 16, 17, 19), a controller (18, 19). The controller in real time monitors (201) the aerosol generator as it is driven for vibration of the aperture plate, and detects (202) a change in an electrical characteristic in response to a transition from a wet state to a dry state of the aperture plate. It automatically modifies (203, 205, 206), during the transition, operation of the aerosol generator in response to the detected change. The modification includes reducing applied power (203). The controller continues (204) to monitor during the transition, including monitoring the aperture plate for presence of residual liquid on the aperture plate first surface. The controller monitors at a number of drive frequencies and maintains data representing trends in a combination of the electrical characteristic signals at the different frequencies, and identifies a start of a transition if a calculated value rises above a threshold. There is one threshold for triggering a check scan for residual volume and a higher threshold to trigger an immediate shut down.
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公开(公告)号:US11065399B2
公开(公告)日:2021-07-20
申请号:US16572298
申请日:2019-09-16
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , B05B17/00 , B06B1/02 , B05B15/14 , G16H20/10 , G16H20/13 , B05B12/00 , B05B12/08
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US20210187209A1
公开(公告)日:2021-06-24
申请号:US17194369
申请日:2021-03-08
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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