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公开(公告)号:US11660404B2
公开(公告)日:2023-05-30
申请号:US17350562
申请日:2021-06-17
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , G01N29/22 , G01N29/42 , B05B17/00 , B05B17/06 , B06B1/02 , B05B15/14 , G16H20/10 , G16H20/13 , B05B12/00 , B05B12/08
CPC classification number: A61M11/005 , A61M11/001 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , G01N29/22 , G01N29/42 , G16H20/10 , G16H20/13 , A61M2205/33 , A61M2205/3317 , B05B12/004 , B05B12/081
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US10449307B2
公开(公告)日:2019-10-22
申请号:US15933082
申请日:2018-03-22
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , G06F19/00 , B05B17/00 , B06B1/02 , G16H20/13 , B05B15/14 , B05B12/00 , B05B12/08
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US20210308387A1
公开(公告)日:2021-10-07
申请号:US17350562
申请日:2021-06-17
Applicant: Stamford Devices Limited
Inventor: Joseph GREHAN , Niall Smith
IPC: A61M11/00 , G01N29/22 , G01N29/42 , B05B17/00 , B05B17/06 , B06B1/02 , B05B15/14 , G16H20/10 , G16H20/13
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US09956356B2
公开(公告)日:2018-05-01
申请号:US14423046
申请日:2014-05-23
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , G06F19/00 , B05B17/00 , B06B1/02 , B05B12/00 , B05B12/08
CPC classification number: A61M11/005 , A61M11/001 , A61M2205/33 , A61M2205/3317 , B05B12/004 , B05B12/081 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , G01N29/22 , G01N29/42 , G06F19/00 , G06F19/3456 , G16H20/13
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US11998678B2
公开(公告)日:2024-06-04
申请号:US17194369
申请日:2021-03-08
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
CPC classification number: A61M11/00 , A61M11/005 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , A61M2205/3317 , A61M2205/3386 , A61M2205/50 , A61M2205/583 , B05B12/081 , B06B2201/77
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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公开(公告)号:US11065399B2
公开(公告)日:2021-07-20
申请号:US16572298
申请日:2019-09-16
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , B05B17/00 , B06B1/02 , B05B15/14 , G16H20/10 , G16H20/13 , B05B12/00 , B05B12/08
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US20210187209A1
公开(公告)日:2021-06-24
申请号:US17194369
申请日:2021-03-08
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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公开(公告)号:US12186477B2
公开(公告)日:2025-01-07
申请号:US18304854
申请日:2023-04-21
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Niall Smith
IPC: A61M11/00 , B05B15/14 , B05B17/00 , B05B17/06 , B06B1/02 , G01N29/22 , G01N29/42 , G16H20/10 , G16H20/13 , B05B12/00 , B05B12/08
Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号:US11833310B2
公开(公告)日:2023-12-05
申请号:US16750507
申请日:2020-01-23
Applicant: Stamford Devices Limited
Inventor: Ronan MacLoughlin , Niall Smith
IPC: A61M16/08 , A61M16/06 , A61M16/16 , A61M16/20 , A61M11/00 , A61M15/08 , A61M16/14 , A61M16/10 , A61M16/00
CPC classification number: A61M16/16 , A61M11/00 , A61M15/08 , A61M16/0666 , A61M16/0833 , A61M16/0866 , A61M16/0875 , A61M16/1095 , A61M16/14 , A61M16/202 , A61M2016/0018 , A61M2016/0027 , A61M2016/0033 , A61M2016/0036 , A61M2205/33 , A61M2205/3334
Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.
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公开(公告)号:US10967138B2
公开(公告)日:2021-04-06
申请号:US15762387
申请日:2016-09-22
Applicant: Stamford Devices Limited
Inventor: Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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