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    Pyrazole derivative
    11.
    发明申请
    Pyrazole derivative 失效
    吡唑衍生物

    公开(公告)号：US20060264430A1

    公开(公告)日：2006-11-23

    申请号：US11399379

    申请日：2006-04-07

    申请人： Hirokazu Kubota ,  Yasuhiro Yonetoku ,  Keizo Sugasawa ,  Masashi Funatsu ,  Souichirou Kawazoe ,  Akira Toyoshima ,  Yoshinori Okamoto ,  Jun Ishikawa ,  Makoto Takeuchi

    发明人： Hirokazu Kubota ,  Yasuhiro Yonetoku ,  Keizo Sugasawa ,  Masashi Funatsu ,  Souichirou Kawazoe ,  Akira Toyoshima ,  Yoshinori Okamoto ,  Jun Ishikawa ,  Makoto Takeuchi

    IPC分类号： A61K31/538 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/454 ,  A61K31/416 ,  C07D413/02 ,  C07D403/02

    CPC分类号： C07D231/12 ,  C07D231/14 ,  C07D233/56 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D417/04 ,  C07D417/12 ,  C07D417/14

    摘要： Drugs, in particular, pyrazole derivatives represented by the following general formula (I) which have a calcium release-activated calcium channel inhibitory effect and medicinal compositions, in particular, calcium release-activated calcium channel inhibitors containing the above compounds as the active ingredient, (in the formula, each symbol has the following meaning: D: pyrazolyl which may have 1 to 3 substituents selected from the group consisting of -Alk, -lower alkenyl, -lower alkynyl, -halogeno-lower alkyl, -Alk-cycloalkyl, -Alk-O-Alk, -cycloalkyl, —O-Alk, —COOH, —COO-Alk and -Hal, n: 0 or 1, B: phenylene, a nitrogen-containing, divalent, saturated ring group, or a monocyclic, divalent heteroaromatic ring group which may be substituted with Alk, X: —NR1—CR2R3—, —CR2R3—NR1—, —NR1—SO2—, —SO2—NR1— or —CR4═CR5—, and A: benzene ring which may have one or more substituents; mono-, di- or tricyclic fused heteroaryl which may have one or more substituents; cycloalkyl which may have one or more substituents; a nitrogen-containing, saturated ring group which may have one or more substituents; lower alkenyl which may have one or more substituents; lower alkynyl which may have one or more substituents; or Alk which may have one or more substituents).

    摘要翻译： 药物，特别是具有钙释放激活的钙通道抑制作用的以下通式（I）表示的吡唑衍生物和药物组合物，特别是含有上述化合物作为活性成分的钙释放激活的钙通道抑制剂， （式中，每个符号具有以下含义：D：吡唑基，其可以具有1〜3个选自-Alk， - 低级烯基， - 低级炔基， - 卤代 - 低级烷基，-Al-环烷基， -Alk-O-Alk， - 环烷基，-O-Alk，-COOH，-COO-Alk和-Hal，n：0或1，B：亚苯基，含氮二价饱和环基或单环 可以被Alk取代的二价杂芳族环基团，X：-NR 1 -CR 2，R 3，...， 2，-NR 3 -NR 1 - ， - NR 1 -SO 2 - ， - SO 2 - ， - SO 2 或者-CR 4 -CR 5 - ，以及可以具有的A：苯环 一个o 更多取代基; 可以具有一个或多个取代基的单 - ，二 - 或三环稠合杂芳基; 可以具有一个或多个取代基的环烷基; 可具有一个或多个取代基的含氮饱和环基; 可以具有一个或多个取代基的低级烯基; 可以具有一个或多个取代基的低级炔基; 或Alk，其可以具有一个或多个取代基）。

    Pyrazole derivative
    13.
    发明授权
    Pyrazole derivative 失效
    吡唑衍生物

    公开(公告)号：US07285554B2

    公开(公告)日：2007-10-23

    申请号：US11399379

    申请日：2006-04-07

    申请人： Hirokazu Kubota ,  Yasuhiro Yonetoku ,  Keizo Sugasawa ,  Masashi Funatsu ,  Souichirou Kawazoe ,  Akira Toyoshima ,  Yoshinori Okamoto ,  Jun Ishikawa ,  Makoto Takeuchi

    发明人： Hirokazu Kubota ,  Yasuhiro Yonetoku ,  Keizo Sugasawa ,  Masashi Funatsu ,  Souichirou Kawazoe ,  Akira Toyoshima ,  Yoshinori Okamoto ,  Jun Ishikawa ,  Makoto Takeuchi

    IPC分类号： C07D231/12 ,  A61K31/415

    CPC分类号： C07D231/12 ,  C07D231/14 ,  C07D233/56 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D417/04 ,  C07D417/12 ,  C07D417/14

    摘要： Drugs, in particular, pyrazole derivatives represented by the following general formula (I) which have a calcium release-activated calcium channel inhibitory effect and medicinal compositions, in particular, calcium release-activated calcium channel inhibitors containing the above compounds as the active ingredient, (in the formula, each symbol has the following meaning: D: pyrazolyl which may have 1 to 3 substituents selected from the group consisting of -Alk, -lower alkenyl, -lower alkynyl, -halogeno-lower alkyl, -Alk-cycloalkyl, -Alk-O-Alk, -cycloalkyl, —O-Alk, —COOH, —COO-Alk and -Hal, n: 0 or 1, B: phenylene, a nitrogen-containing, divalent, saturated ring group, or a monocyclic, divalent heteroaromatic ring group which may be substituted with Alk, X: —NR1—CR2R3—, —CR2R3—NR1—, —NR1—SO2—, —SO2—NR1— or —CR4═CR5—, and A: benzene ring which may have one or more substituents; mono-, di- or tricyclic fused heteroaryl which may have one or more substituents; cycloalkyl which may have one or more substituents; a nitrogen-containing, saturated ring group which may have one or more substituents; lower alkenyl which may have one or more substituents; lower alkynyl which may have one or more substituents; or Alk which may have one or more substituents).

    摘要翻译： 药物，特别是具有钙释放激活的钙通道抑制作用的以下通式（I）表示的吡唑衍生物和药物组合物，特别是含有上述化合物作为活性成分的钙释放激活的钙通道抑制剂， （式中，每个符号具有以下含义：D：吡唑基，其可以具有1〜3个选自-Alk， - 低级烯基， - 低级炔基， - 卤代 - 低级烷基，-Al-环烷基， -Alk-O-Alk， - 环烷基，-O-Alk，-COOH，-COO-Alk和-Hal，n：0或1，B：亚苯基，含氮二价饱和环基或单环 可以被Alk取代的二价杂芳族环基团，X：-NR 1 -CR 2，R 3，...， 2，-NR 3 -NR 1 - ， - NR 1 -SO 2 - ， - SO 2 - ， - SO 2 或者-CR 4 -CR 5 - ，以及可以具有的A：苯环 一个o 更多取代基; 可以具有一个或多个取代基的单 - ，二 - 或三环稠合杂芳基; 可以具有一个或多个取代基的环烷基; 可具有一个或多个取代基的含氮饱和环基; 可以具有一个或多个取代基的低级烯基; 可以具有一个或多个取代基的低级炔基; 或Alk，其可以具有一个或多个取代基）。

    Bearing structure using resin bush
    14.
    发明授权
    Bearing structure using resin bush 有权
    轴承结构采用树脂衬套

    公开(公告)号：US08827369B2

    公开(公告)日：2014-09-09

    申请号：US12978835

    申请日：2010-12-27

    申请人： Hiroshi Izawa ,  Makoto Takeuchi ,  Takahiro Kobori

    发明人： Hiroshi Izawa ,  Makoto Takeuchi ,  Takahiro Kobori

    IPC分类号： A47C7/54 ,  B60N2/46 ,  F16C17/00 ,  F16C17/02 ,  F16C33/20

    CPC分类号： A47C7/54 ,  B60N2/753 ,  F16C17/02 ,  F16C33/20 ,  F16C2208/66 ,  F16C2208/76 ,  Y10T403/3981

    摘要： According to a first aspect of the invention, there is provided a bearing structure including: a resin bush having a flange formed to be brought into contact with a plate face around a bearing hole from one side, a locking edge formed to be locked with the plate face around the bearing hole from the other side, and a circular through-hole formed to bear the support shaft inserted therethrough, wherein, upon receiving a load applied to the support shaft, the entire resin bush is flexibly displaced so that an inner circumferential surface of the through-hole is aligned with a hole edge of the bearing hole and the support shaft is born by the hole edge of the bearing hole.

    摘要翻译： 根据本发明的第一方面，提供了一种轴承结构，其包括：树脂衬套，其具有形成为与来自一侧的轴承孔周围的板面接触的凸缘，形成为与所述轴承孔锁定的锁定边缘 板形面从另一侧围绕轴承孔，形成为承载插入其中的支撑轴的圆形通孔，其中，在接收到施加到支撑轴上的负载时，整个树脂衬套被灵活地移位，使得内周 通孔的表面与轴承孔的孔边缘对齐，支撑轴由轴承孔的孔边缘承受。

    Heat engine
    15.
    发明授权
    Heat engine 有权
    热机

    公开(公告)号：US08640453B2

    公开(公告)日：2014-02-04

    申请号：US12821859

    申请日：2010-06-23

    申请人： Makoto Takeuchi

    发明人： Makoto Takeuchi

    IPC分类号： F01B29/08 ,  F01K25/00 ,  F01B29/10 ,  F02G1/04

    CPC分类号： F02G1/044 ,  F02G2243/06

    摘要： A heat engine includes: a high-temperature space portion and a low-temperature space portion, each of which has a working gas with a different temperature range from each other; a regenerator provided between both of the space portions; a first piston configured to cause volumetric changes of the working gases in the space portions and transmit motive energy on receipt of pressure changes of the working gases; and a second piston and a third piston configured to transfer the working gases between both of the space portions and move with a 180° phase difference from each other with respect to the regenerator. The second piston is slidably housed in a cylinder portion included in the first piston. Heat and motive energy are exchanged by using the volumetric changes in both of the space portions, as well as by using the transfer of the working gases.

    摘要翻译： 热机包括：高温空间部分和低温空间部分，每个部分具有彼此具有不同温度范围的工作气体; 设置在两个空间部分之间的再生器; 第一活塞构造成在空间部分中引起工作气体的体积变化，并在接收到工作气体的压力变化时传递动能; 以及第二活塞和第三活塞，其构造成在两个空间部分之间传递工作气体，并相对于再生器以180°的相位差移动。 第二活塞可滑动地容纳在包括在第一活塞中的气缸部分中。 通过使用两个空间部分中的体积变化以及通过使用工作气体的转移来交换热量和动能。

    Fluid machine
    16.
    发明授权
    Fluid machine 有权
    流体机

    公开(公告)号：US08628315B2

    公开(公告)日：2014-01-14

    申请号：US12442810

    申请日：2007-09-25

    申请人： Hajime Sato ,  Makoto Takeuchi ,  Hiroshi Yamazaki ,  Shinta Mishima ,  Kazuhide Watanabe

    发明人： Hajime Sato ,  Makoto Takeuchi ,  Hiroshi Yamazaki ,  Shinta Mishima ,  Kazuhide Watanabe

    IPC分类号： F01C1/02

    CPC分类号： F04C18/0215 ,  F01C17/06 ,  F01C17/063 ,  F04C2250/00 ,  F04C2270/16

    摘要： Intended is to provide a fluid machine that can prevent wear of a rotation preventing pin. The fluid machine includes a housing, a fixed scroll fixed with respect to the housing, a turning scroll that revolves around the fixed scroll, and a rotation preventing mechanism that prevents the rotation of the turning scroll. The rotation preventing mechanism includes a rotation preventing pin projected from a wall surface at the housing side or the turning scroll side, and a restraining member that restricts the position of the rotation preventing pin by engaging with the rotation preventing pin. A projecting side end of the rotation preventing pin has a taper shape, and the end of the taper shape has an R-shape.

    摘要翻译： 旨在提供一种能够防止旋转阻止销的磨损的流体机器。 流体机械包括壳体，相对于壳体固定的固定涡旋件，围绕固定涡旋件旋转的转动涡旋件，以及防止转动涡旋件旋转的旋转防止机构。 旋转防止机构包括从壳体侧或转动涡卷侧的壁面突出的防旋转销，以及通过与旋转防止销接合而限制防转动销的位置的限制部件。 防旋转销的突出侧端部具有锥形形状，并且锥形形状的端部具有R形状。

    Scroll type compressor having an elastic member to suppress noise and reduce variations
    17.
    发明授权
    Scroll type compressor having an elastic member to suppress noise and reduce variations 有权
    涡旋式压缩机具有弹性部件，以抑制噪音并减小变化

    公开(公告)号：US08602756B2

    公开(公告)日：2013-12-10

    申请号：US13142194

    申请日：2009-12-22

    申请人： Makoto Takeuchi ,  Takayuki Suzuki ,  Masahiro Ohta ,  Kazuhide Watanabe

    发明人： Makoto Takeuchi ,  Takayuki Suzuki ,  Masahiro Ohta ,  Kazuhide Watanabe

    IPC分类号： F03C4/00 ,  F04C2/00 ,  F04C18/00

    CPC分类号： F04C18/0215 ,  F04C29/0021 ,  F04C29/06 ,  F04C2240/60 ,  F04C2270/12

    摘要： Provided is a scroll type compressor which reduces variations in the pressing load of a rotating scroll on a fixed scroll, reduces the impact at the start of the compressor and suppresses noises, and can provide excellent durability. A peripheral elastic body 51 and a bottom-portion elastic body 52, which is brought into a compressed condition in the axis line direction of the main shaft 31, are interposed between a stopper pin 41 on the rotating scroll side and a concave portion 42 on the main shaft 31 side, whereby working errors of each part are compensated and the rotating scroll is constantly brought into close contact with the fixed scroll to maintain the sealing of the compression chamber.

    摘要翻译： 本发明提供一种能够降低固定涡旋盘上的旋转涡旋件的按压负荷变动的涡旋式压缩机，能够降低压缩机起动时的冲击，抑制噪音，能够提供优异的耐久性。 在主轴31的轴线方向上被压缩状态的周向弹性体51和底部弹性体52插入在旋转涡旋面侧的止动销41和位于旋转涡旋侧的凹部42之间 主轴31侧，由此补偿各部件的作业误差，并且使旋转涡卷恒定地与固定涡旋件紧密接触，以保持压缩室的密封。

    Fender protector structure
    19.
    发明授权
    Fender protector structure 有权
    挡泥板保护结构

    公开(公告)号：US07909392B2

    公开(公告)日：2011-03-22

    申请号：US12329805

    申请日：2008-12-08

    申请人： Makoto Takeuchi ,  Hitoshi Nito

    发明人： Makoto Takeuchi ,  Hitoshi Nito

    IPC分类号： B62D25/16

    CPC分类号： B62D25/161 ,  Y10T29/49826

    摘要： A fender protector structure of a vehicle which includes a body structure including a body panel and a fender panel. The body structure defines a wheel well. A fender protector is connected to the body structure for covering an outer periphery of the wheel well, and a reinforcing structure for the fender protector extends from the body panel to the fender panel, wherein the reinforcing structure includes fixing the fender protector to the body panel.

    摘要翻译： 一种车辆的挡泥板保护结构，其包括主体结构，其包括车身板和挡泥板。 车身结构定义了车轮井。 翼子板保护器连接到主体结构以覆盖车轮井的外周，并且用于挡泥板保护器的加强结构从车身板延伸到翼子板，其中，加强结构包括将翼子板保护器固定到车身板 。

    Torque fluctuation absorbing apparatus
    20.
    发明授权
    Torque fluctuation absorbing apparatus 有权
    扭矩波动吸收装置

    公开(公告)号：US07828663B2

    公开(公告)日：2010-11-09

    申请号：US11979805

    申请日：2007-11-08

    申请人： Tomohiro Saeki ,  Makoto Takeuchi ,  Masanori Suzuki ,  Yasuhiro Enya

    发明人： Tomohiro Saeki ,  Makoto Takeuchi ,  Masanori Suzuki ,  Yasuhiro Enya

    IPC分类号： F16D7/02

    CPC分类号： F16F15/1297

    摘要： A torque fluctuation absorbing apparatus including a limiter mechanism includes: a disc member connected to one of the driving-side member and the driven-side member, a first plate and a second plate connected to the other one of the driving-side member and the driven-side member; a frictional member fixed to the disc member and interposed between the first plate and the second plate, the frictional member including a frictional surface slidably in contact with the first and second plates. The frictional member includes a fibrous substrate and is formed with a plurality of grooves at the frictional surface. A minimum dimension between two adjacent grooves from among the plurality of grooves is designed to be greater than or equal to 2 mm and smaller than or equal to 7 mm.

    摘要翻译： 包括限幅器机构的扭矩波动吸收装置包括：连接到驱动侧构件和从动侧构件中的一个的盘构件，与驱动侧构件和从动侧构件中的另一个连接的第一板和第二板 从动侧构件; 固定到所述盘构件并且介于所述第一板和所述第二板之间的摩擦构件，所述摩擦构件包括可滑动地与所述第一和第二板接触的摩擦面。 摩擦构件包括纤维基底，并且在摩擦表面处形成有多个凹槽。 多个凹槽中的两个相邻凹槽之间的最小尺寸设计成大于或等于2mm且小于或等于7mm。