公开(公告)号：US10584097B2

公开(公告)日：2020-03-10

申请号：US16577449

申请日：2019-09-20

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Yuichi Kajita ,  Yuhei Miyanohana ,  Tatsuki Koike ,  Kohei Takeuchi ,  Yoshiteru Ito ,  Norihito Tokunaga ,  Takahiro Sugimoto ,  Tohru Miyazaki ,  Tsuneo Oda ,  Yasutaka Hoashi ,  Yasushi Hattori ,  Keisuke Imamura

IPC: C07D211/56 ,  C07D405/06 ,  C07D205/04 ,  C07D207/14 ,  C07D401/06 ,  C07D401/10 ,  C07D401/14 ,  C07D403/06 ,  C07D405/10 ,  C07D405/12 ,  C07D413/06 ,  C07D417/06 ,  C07D417/14 ,  C07D211/36 ,  A61P25/00

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof, is useful as an agent for the prophylaxis or treatment of narcolepsy.

公开(公告)号：US10577382B2

公开(公告)日：2020-03-03

申请号：US16094030

申请日：2017-04-27

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Youichi Kawakita ,  Takuto Kojima ,  Noriyuki Nii ,  Yoshiteru Ito ,  Nobuki Sakauchi ,  Hiroshi Banno ,  Xin Liu ,  Koji Ono ,  Keisuke Imamura ,  Shinichi Imamura

IPC: C07D519/00 ,  A61K31/53 ,  A61P35/00

Abstract: Provided is a compound represented by the following formula, or a salt thereof: [wherein each symbol is as defined herein].