公开(公告)号：US11122982B2

公开(公告)日：2021-09-21

申请号：US16090083

申请日：2017-04-03

Applicant: The Regents of the University of California

Inventor： Joseph Wang ,  Patrick Mercier

IPC: A61B5/02 ,  A61B5/0205 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1468 ,  A61B5/259 ,  A61B5/282 ,  A61B5/318 ,  A61B5/08 ,  A61B5/145 ,  A61B5/1486

Abstract: Methods, systems, and devices are disclosed for wearable, real-time multimodal sensing of electrochemical and electrophysiological and/or physical parameters of a user. In some aspects, a multimodal sensor device includes a flexible substrate; an electrochemical sensor disposed on the substrate and including electrochemical sensing electrodes operable to measure an electrical signal corresponding to a reaction including a chemical substance via an electrochemical sensing electrode and an analyte at the electrochemical sensor; and an electrophysiological sensor including two or more electrodes disposed on the substrate to acquire an electrophysiological signal of the user, such that when the multimodal sensor device is electrically coupled to an electronics unit and adhered to the user, the device is operable to simultaneously monitor an electrochemical parameter and an electrophysiological parameter of the user.

公开(公告)号：US20200253520A1

公开(公告)日：2020-08-13

申请号：US16785507

申请日：2020-02-07

Applicant: The Regents of the University of California

Inventor： Joseph Wang ,  Patrick Mercier ,  Ali Fazli Yeknami ,  Somayeh Imani

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  H01M8/16 ,  H01M8/04858 ,  G01N27/327

Abstract: Disclosed are self-powering biofuel cell and sensor devices, systems and techniques. In some aspects, a self-powered biosensing system includes an electronic circuit; an anode including an enzymatic layer electrically coupled to a power supply voltage terminal of the electronic circuit and configured to interact with an analyte in a fluid, such as glucose or lactate; and a cathode electrically coupled to a ground voltage terminal of the electronic circuit, where the electronic circuit is operable to control and use the electrical energy generated at the anode and cathode for powering the biosensing system and detecting a concentration of the analyte in the fluid.

公开(公告)号：US10374511B2

公开(公告)日：2019-08-06

申请号：US15545614

申请日：2016-01-29

Applicant: The Regents of the University of California

Inventor： Loai Galal Bahgat Salem ,  Patrick Mercier

IPC: H02M3/07

Abstract: A scalable controller circuit that provides faster and simpler regulation of a DC-to-DC converter is provided. Unlike such prior techniques, preferred embodiments do not require any threshold-level generation circuitry or analog compensation circuitry. Preferred embodiments implement a simple control law that requires only a few digital gates. Preferred embodiments can therefore significantly reduce the overhead power consumption and area of the controller in DC-to-DC converters to new levels.

公开(公告)号：US20190101947A1

公开(公告)日：2019-04-04

申请号：US16099400

申请日：2017-05-18

Applicant: The Regents of the University of California

Inventor： Patrick Mercier ,  Hui Wang

IPC: G05F3/26 ,  G01K7/01

Abstract: An ultra-low-power voltage reference generator in an integrated CMOS circuit includes a regular MOS transistor reference current source connected to a line voltage and a regular MOS transistor resistor between the regular MOS transistor reference current source and ground. A constant with temperature reference voltage VREF is generated from a terminal inter-connecting the regular MOS transistor reference current source and the regular MOS transistor resistor. An ultra-low-power current reference generator receives a reference voltage and generated ultra-low level current from the reference voltage with a temperature compensated gate-leakage array.

公开(公告)号：US20240030800A1

公开(公告)日：2024-01-25

申请号：US18252607

申请日：2021-11-16

Applicant: The Regents of the University of California

Inventor： Patrick Mercier ,  Abdullah Abdulslam

IPC: H02M1/00 ,  H02M3/158 ,  H02M3/07

CPC classification number: H02M1/0054 ,  H02M3/158 ,  H02M3/07

Abstract: A charge recycling circuit in an integrated circuit DC-DC converter having two power MOSFETs, the charge recycling circuit comprising a single inductor and recycling MOSFET switches arranged and sized such that when one of the two power MOSFETs is turning off, its gate capacitance charges are transferred to the single inductor, stored in the single inductor and then transferred directly to the gate of the other power MOSFET to turn it on.

公开(公告)号：US20230119392A1

公开(公告)日：2023-04-20

申请号：US17799409

申请日：2021-02-12

Applicant: The Regents of the University of California

Inventor： Po-Han Wang ,  Patrick Mercier ,  Dinesh Bharadia

IPC: H04W52/02

Abstract: A method for communicating directly with commodity Wi-Fi transceivers (TRXs) via backscatter modulation in an integrated tag device is provided. The method includes sensing an incident Wi-Fi?compliant wake-up signal. The method than reflects the incident Wi-Fi- complaint wake-up signal by encoding data from the tag device such that the reflected signal follows the Wi-Fi standard compliant and can be decoded by another WiFi-device. An integrated device includes a downlink Wi-Fi compatible wake-up receiver that checks timing of Wi-Fi compatible signals for a wake-up packet. The device has a modulator that is turned on in response to the wake-up packet and a mixer in the modulator hat mixes tag data with a payload packet from received Wi-Fi payload. Backscatter switches backscatter the response.

公开(公告)号：US20230111253A1

公开(公告)日：2023-04-13

申请号：US17904284

申请日：2021-02-22

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Joseph Wang ,  Farshad E. Tehrani ,  Patrick Mercier ,  Christopher Brown ,  Hazhir Teymourian

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/00

Abstract: Disclosed are systems, devices and methods for continuous and simultaneous monitoring of multiple analytes within interstitial fluid by an integrated system for a microneedle array sensor platform. In some aspects, the device includes a microneedle array sensor unit, an electronics unit and a housing structure. The electronics unit is in electrical communication with an array of electrode probe structures via an array of surface-mount, spring loaded pins, and the electronics unit includes a power source, a data processing unit, and a wireless transmitter. The housing structure is configured to encase, at least partially, the microneedle array sensor unit and the electronics unit, where the array of microneedles is exposed from a side of the housing structure. The device can be configured as a patch worn on skin of a patient user.

公开(公告)号：US20200367793A1

公开(公告)日：2020-11-26

申请号：US16789316

申请日：2020-02-12

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Joseph Wang ,  Patrick Mercier

IPC: A61B5/1486 ,  A61C19/04 ,  A61B5/00 ,  A61B5/145 ,  H01M8/16

Abstract: Methods, systems, and devices are disclosed mouth-based biosensors and biofuel cells. In one aspect, an electrochemical sensor device for detecting analytes in saliva includes a substrate including an electrically insulative material, a first electrode disposed on the substrate at a first location, in which the first electrode includes a surface including a chemical agent (e.g., a catalyst or a reactant) corresponding to an analyte in saliva; and a second electrode disposed on the substrate at a second location separated from the first electrode by a spacing region, the first and second electrodes capable of sustaining a redox reaction involving the chemical agent and the analyte to produce an electrical signal, such that, when the device is present in the mouth of a user and electrically coupled to an electrical circuit, the device is operable to detect the analyte in the user's saliva.

公开(公告)号：US10729379B2

公开(公告)日：2020-08-04

申请号：US15031142

申请日：2014-10-21

Applicant: The Regents of the University of California

Inventor： Chung-Kuan Cheng ,  Patrick Mercier ,  Shih-Hung Weng

IPC: A61B5/00 ,  A61B5/0428 ,  A61B5/0408

Abstract: A biosensor of the invention is a capacitive noncontact sensor with two sensor channels split into a plurality of physically interdigitated symmetrical electrodes and shield sections. Two capacitive plates are electrically connected to the two sensor channels. The capacitive noncontact sensor is sized and packaged to be worn by a person to place the capacitive plates close to the skin of the person and form first and second channel input capacitors with the skin. A signal reconstruction circuit obtains a bio signal from the first and second channel input capacitors through the electrodes by reconstructing differences in the two sensor channels. The circuit includes different parasitic input capacitance in the two channels to create channel-specific outputs that depend on input coupling capacitance.

公开(公告)号：US20200229088A1

公开(公告)日：2020-07-16

申请号：US16742476

申请日：2020-01-14

Applicant: The Regents of the University of California

Inventor： Po-Han Wang ,  Patrick Mercier

IPC: H04W52/02 ,  H04W28/02 ,  H04W40/12 ,  H04W4/80

Abstract: A low-power wake-up receiver includes a mixer-based two-stage heterodyne architecture that provides multi-stage channel filtering, including a combination of circuits and a digital signal processor that process energy in a plurality of advertising channels to detect a four-dimensional wake-up signature via frequency-hopping among the plurality of advertising channels. One receiver is a BLE/Wi-Fi dual-mode wake-up receiver.