摘要:
The present invention relates to preventives or remedies for Alzheimer's disease, or to amyloid protein fibril-formation inhibitors, which include as an active ingredient a compound of general formula (I) below or a pharmacologically permitted salt thereof; and also to nitrogen-containing heteroaryl derivatives having specific substituents, or pharmacologically permitted salts thereof, which are valuable as preventives or remedies for Alzheimer's disease, or as amyloid protein fibril-formation inhibitors: (where, R1 and R2 are H or alkyl; Z1 and Z2 are H, alkyl, alkoxy, haloalkyl or halogeno; Z3 is alkoxy, SH, alkylthio, NH2, mono- or di-alkylamino, OH or halogeno; Z4 and Z5 are H or halogeno; and A is 4,6-pyrimidine-1,3-diyl, 1,3,5-triazine-2,6-diyl, etc).
摘要:
An exhaust emission control device for an internal combustion engine, which is capable of terminating reduction control in proper timing when a NOx cleaning catalyst includes an auxiliary catalyst having an oxygen storage capacity, thereby making it possible to reduce exhaust emissions and improve fuel economy. The exhaust emission control device includes the NOx cleaning catalyst and an ECU. The NOx cleaning catalyst includes the auxiliary catalyst having an oxygen storage capacity. The ECU executes reduction control when predetermined conditions for executing the reduction control are satisfied. During execution of the reduction control, when exhaust gas temperature is higher than a predetermined value, if a second excess air ratio is lower than a predetermined value, the ECU determines that the reduction control should be terminated. When the exhaust gas temperature is not higher than the predetermined value, if the remaining NOx amount is not larger than a predetermined value, the ECU determines that the reduction control should be terminated.
摘要:
A 3,4-dihalogenoisothiazole derivative represented by the general formula [I] (wherein R1 is a halogen atom; A is an oxygen atom or a sulfur atom; and R is a C1-C6 alkyl group, a C2-C5 alkenyl group, a C2-C5 alkynyl group, a C3-C6 cycloalkyl group, a phenyl group or a 5- to 10-membered heterocyclic group containing at least one of oxygen atom, sulfur atom and nitrogen atom), or a salt thereof.
摘要翻译:由通式[I]表示的3,4-二卤代异噻唑衍生物(其中R1是卤素原子; A是氧原子或硫原子; R是C1-C6烷基,C2-C5烯基, C 2 -C 5炔基,C 3 -C 6环烷基,苯基或含有氧原子,硫原子和氮原子中的至少一个的5元至10元杂环基)或其盐。
摘要:
An exhaust emission control device for an internal combustion engine, which is capable of terminating reduction control in proper timing when a NOx cleaning catalyst includes an auxiliary catalyst having an oxygen storage capacity, thereby making it possible to reduce exhaust emissions and improve fuel economy. The exhaust emission control device includes the NOx cleaning catalyst and an ECU. The NOx cleaning catalyst includes the auxiliary catalyst having an oxygen storage capacity. The ECU executes reduction control when predetermined conditions for executing the reduction control are satisfied. During execution of the reduction control, when exhaust gas temperature is higher than a predetermined value, if a second excess air ratio is lower than a predetermined value, the ECU determines that the reduction control should be terminated. When the exhaust gas temperature is not higher than the predetermined value, if the remaining NOx amount is not larger than a predetermined value, the ECU determines that the reduction control should be terminated.
摘要:
The invention provides a sound-reproducing apparatus and a high frequency interpolation-processing method in each of which high frequency interpolation processing having a light burden imposed thereon can be executed. Compressed audio data is decoded by a decoder (202a) and the resulting audio signal is transmitted to a harmonizer (209a). Auxiliary information such as a sampling rate and a bit rate contained in the decoded audio signal is read out by a header reader (209b) and is transmitted to a harmonizer (209a). Communication of signals from/to respective portions is made through a bus (210). The harmonizer (209a) has a preset for an interpolation band obtained in accordance with a format and a sampling frequency of the compressed audio data, and executes processing by referring to file information transmitted thereto from the header reader (209b).
摘要:
The present invention aims to provide a chip-type solid electrolytic capacitor of large capacitance and low ESR. An element section of the capacitor is composed of an anode oxide film layer which functions as a dielectric, a solid electrolyte layer including conductive polymer and a cathode conductive body, which are stacked on a metallic electrode. A plurality of flat capacitor elements with the element section and an anode pulling-out section are stacked, and a laminated unit is produced where the cathode conductive layer and the anode pulling-out section of the flat capacitor elements are connected to a single metallic terminal member each. The solid electrolytic capacitor of the present invention has at least two laminated units placed parallel to each other, and connected to a transversely disposed comb terminal. The construction presented by the present invention achieves a solid electrolytic capacitor of a large capacitance and a low ESR without expanding its mounting surface area.
摘要:
An isoxazole compound having the following formula: ##STR1## wherein R.sup.1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy, alkoxycarbonyl, carboxy, (alkylthio)thiocarbonyl, carbamoyl, nitro or cyano; R.sup.2 represents an amino; m is 2 or 3; n is 1 to 6; ring A represents a phenyl ring, a naphthyl ring or an aromatic heterocycle; and X represents oxygen or sulfur. The isoxazole compound has an excellent monoamine oxidase inhibitory activity, and is useful for treating Parkinson's disease, depression and Alzheimer's disease.
摘要:
The administration of Factor I and/or Factor H to a mammal has been found to alleviate or prevent such autoimmune diseases as systemic lupus erythematosus, rheumatoid arthritis and glomerulonephritis.
摘要:
A 1,2-benzoisothiazole derivative or a salt thereof is not harmful to a crop and is remarkably effective against agricultural or horticultural plant diseases such as Pyricularia oryzae, Septoria nodorum, Pseudoperonospora cubensis and Colletotrichum orbiculare, and an agricultural or horticultural plant disease-controlling agent containing the derivative or its salt as an active ingredient. The 1,2-benzoisothiazole derivative is represented by the general formula [I]: (wherein R1 is a hydrogen atom or a halogen atom, and R2 is a methyl group or a halogen atom), or a salt thereof.
摘要:
The present invention relates to preventives or remedies for Alzheimer's disease, or to amyloid protein fibril-formation inhibitors, which include as an active ingredient a compound of general formula (I) below or a pharmacologically permitted salt thereof; and also to nitrogen-containing heteroaryl derivatives having specific substituents, or pharmacologically permitted salts thereof, which are valuable as preventives or remedies for Alzheimer's disease, or as amyloid protein fibril-formation inhibitors: (where, R1 and R2 are H or alkyl; Z1 and Z2 are H, alkyl, alkoxy, haloalkyl or halogeno; Z3 is alkoxy, SH, alkylthio, NH2, mono- or di-alkylamino, OH or halogeno; Z4 and Z5 are H or halogeno; and A is 4,6-pyrimidine-1,3-diyl, 1,3,5-triazine-2,6-diyl, etc).