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11.发明申请公开(公告)号：US20090123521A1
公开(公告)日：2009-05-14
申请号：US11983796
申请日：2007-11-09
Applicant: Jan Weber , Aiden Flanagan , Tim O'Connor , Barry J. O'Brien , John Clarke , David McMorrow
Inventor： Jan Weber , Aiden Flanagan , Tim O'Connor , Barry J. O'Brien , John Clarke , David McMorrow
IPC: A61F2/00 , A61K31/337 , A61N1/04
CPC classification number: A61F2/06 , A61F2250/0068 , A61L27/30 , A61L27/54 , A61L31/082 , A61L31/16 , A61L2300/00 , A61L2400/12 , A61N1/05
Abstract: According to an aspect of the invention, medical devices are provided, which include a nanoparticle-derived inorganic layer disposed over a least a portion of structure that includes a substrate, and optionally, a therapeutic-agent-containing layer disposed over at least a portion of the substrate. In some embodiments, the inorganic layer is a nanoporous inorganic layer. Other aspects of the invention comprise methods for forming such medical device.
Abstract translation: 根据本发明的一个方面，提供了医疗装置，其包括设置在包括基底的结构的至少一部分上的纳米颗粒衍生的无机层，以及任选地，设置在至少一部分上的治疗剂含有层 的基底。 在一些实施方案中，无机层是纳米多孔无机层。 本发明的其它方面包括用于形成这种医疗装置的方法。
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公开(公告)号：US20090081271A1
公开(公告)日：2009-03-26
申请号：US11860188
申请日：2007-09-24
Applicant: John Clarke , Tim O'Connor , Yixin Xu , Barry J. O'Brien
Inventor： John Clarke , Tim O'Connor , Yixin Xu , Barry J. O'Brien
CPC classification number: A61F2/82 , A61F2/00 , A61F2/01 , A61F2/04 , A61F2/91 , A61F2220/0058 , A61F2250/0068
Abstract: An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a pre-formed filter insert disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device in vivo.
Abstract translation: 提供了一种植入式或可插入的医疗装置，其包括作为部件：（a）底物组分，其包含至少部分地填充有包含第一治疗剂的治疗剂材料的凹陷，和（b）预形成 过滤器插入件设置在凹陷中，使得其在体内植入或插入装置时调节化学物质在装置的凹陷和外部之间的运输。
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13.发明申请公开(公告)号：US20060206191A1
公开(公告)日：2006-09-14
申请号：US11431826
申请日：2006-05-11
Applicant: Jan Weber , Tim O'Connor
Inventor： Jan Weber , Tim O'Connor
IPC: A61F2/84
CPC classification number: A61M25/104 , A61F2/958 , A61F2002/9583 , A61M25/1027 , A61M2025/1081
Abstract: In order to minimize the potential for damage to bio-compatible and/or therapeutic-containing stent coatings, there is provided a compliant elastic sheath over layer between a non-compliant stent expansion balloon and an unexpanded stent, which is secured over the balloon with a securing crimp. This stent deployment assembly, which is mounted on a catheter, is maneuvered through a patient's body to a desired deployment site and then inflated to expand the stent to the desired diameter. During expansion, the compliant elastic material between the stent and the non-compliant balloon prevents non-compliant balloon-induced damage to the stent's coating, as well as preventing degradation of the non-compliant balloon by, for example, stent-caused punctures. The deflated non-compliant stent expansion balloon and compliant elastic sheath are then withdrawn from the patient's body, leaving the deployed stent at the desired implantation site with its coating substantially intact.
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公开(公告)号：US20060136871A1
公开(公告)日：2006-06-22
申请号：US10905173
申请日：2004-12-20
Applicant: Tim O'Connor , Eric Seal , Michael Inniss
Inventor： Tim O'Connor , Eric Seal , Michael Inniss
IPC: G06F9/44
CPC classification number: G06Q10/06
Abstract: A method for holistic project management may include presenting a graphical user interface for a user to enter project information for a project. The method may also include determining a priority for the project based on an impact of the project to each of a plurality of predetermined drivers.
Abstract translation: 用于整体项目管理的方法可以包括呈现图形用户界面，供用户输入项目的项目信息。 该方法还可以包括基于项目对多个预定驱动器中的每一个的影响来确定项目的优先级。
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15.发明申请Apparatus and method for fine bore orifice spray coating of medical devices and pre-filming atomization 审中-公开医疗器械细孔喷雾涂层和预成膜雾化的装置和方法公开(公告)号：US20060038027A1
公开(公告)日：2006-02-23
申请号：US11237685
申请日：2005-09-29
Applicant: Tim O'Connor , Gabriel Sobrino
Inventor： Tim O'Connor , Gabriel Sobrino
CPC classification number: B05B7/066
Abstract: An apparatus and method for spray deposition of small targets, such as medical devices like stents. The apparatus includes a spray nozzle body which has a fine bore diameter to pressurize the coating material within the nozzle body thereby dampening vibration of the nozzle body during operation and stabilizing the spray coating plume. In another embodiment, a coating method is disclosed in which a finer atomized spray droplet size is achieved by pre-filming the coating material onto a flat face before entraining the coating material within the atomizing fluid, which improves manufacturing repeatability, reduces coating variances, and increases therapeutic dosage predictability. In certain embodiments of the invention, the coating materials include therapeutic agents and biologically active materials.
Abstract translation: 用于喷雾沉积小靶的装置和方法，例如诸如支架的医疗装置。 该装置包括具有细孔直径以对喷嘴体内的涂层材料加压的喷嘴体，从而在操作期间抑制喷嘴体的振动并稳定喷涂羽流。 在另一个实施方案中，公开了一种涂覆方法，其中通过在夹带雾化流体内的涂层材料之前将涂层材料预成膜到平坦的表面上来实现更精细的雾化喷雾液滴尺寸，这提高了制造重复性，降低了涂层的变化， 增加治疗剂量可预测性。 在本发明的某些实施方案中，涂层材料包括治疗剂和生物活性材料。
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Patent Agency Ranking
16.发明授权Method for fine bore orifice spray coating of medical devices and pre-filming atomization 有权医疗器械的细孔喷雾涂层和预成膜雾化的方法公开(公告)号：US06979473B2
公开(公告)日：2005-12-27
申请号：US10799589
申请日：2004-03-15
Applicant: Tim O'Connor , Gabriel Sobrino
Inventor： Tim O'Connor , Gabriel Sobrino
CPC classification number: B05B7/066
Abstract: A method for spray deposition of small targets, such as medical devices like stents. The method includes the steps of positioning a spray nozzle body, which has a fine bore diameter to pressurize the coating material within the nozzle body, near a medical device, and dampening vibration of the nozzle body during operation by maintaining a steady back pressure in the coating material line sufficient to eliminate or minimize vibration modes from external and internal sources; and stabilizing the spray coating plume. In another embodiment, a coating method is disclosed in which a finer atomized spray droplet size is achieved by pre-filming the coating material onto a flat face before entraining the coating material within the atomizing fluid, which improves manufacturing repeatability, reduces coating variances, and increases therapeutic dosage predictability. In certain embodiments of the invention, the coating materials include therapeutic agents and biologically active materials.
Abstract translation: 用于喷雾沉积小靶的方法，例如诸如支架的医疗装置。 该方法包括以下步骤：定位喷嘴体，其具有细孔直径以在喷嘴体内靠近医疗装置加压涂层，以及在操作期间通过保持稳定的背压来抑制喷嘴体的振动 涂层材料线足以消除或最小化来自外部和内部源的振动模式; 并稳定喷涂羽流。 在另一个实施方案中，公开了一种涂覆方法，其中通过在夹带雾化流体内的涂层材料之前将涂层材料预成膜到平坦的表面上来实现更精细的雾化喷雾液滴尺寸，这提高了制造重复性，降低了涂层的变化， 增加治疗剂量可预测性。 在本发明的某些实施方案中，涂层材料包括治疗剂和生物活性材料。
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17.发明申请公开(公告)号：US20050202156A1
公开(公告)日：2005-09-15
申请号：US10799589
申请日：2004-03-15
Applicant: Tim O'Connor , Gabriel Sobrino
Inventor： Tim O'Connor , Gabriel Sobrino
CPC classification number: B05B7/066
Abstract: A method for spray deposition of small targets, such as medical devices like stents. The method includes the steps of positioning a spray nozzle body, which has a fine bore diameter to pressurize the coating material within the nozzle body, near a medical device, and dampening vibration of the nozzle body during operation by maintaining a steady back pressure in the coating material line sufficient to eliminate or minimize vibration modes from external and internal sources; and stabilizing the spray coating plume. In another embodiment, a coating method is disclosed in which a finer atomized spray droplet size is achieved by pre-filming the coating material onto a flat face before entraining the coating material within the atomizing fluid, which improves manufacturing repeatability, reduces coating variances, and increases therapeutic dosage predictability. In certain embodiments of the invention, the coating materials include therapeutic agents and biologically active materials.
Abstract translation: 用于喷雾沉积小靶的方法，例如诸如支架的医疗装置。 该方法包括以下步骤：定位喷嘴体，其具有细孔直径以在喷嘴体内靠近医疗装置加压涂层，以及在操作期间通过保持稳定的背压来抑制喷嘴体的振动 涂层材料线足以消除或最小化来自外部和内部源的振动模式; 并稳定喷涂羽流。 在另一个实施方案中，公开了一种涂覆方法，其中通过在夹带雾化流体内的涂层材料之前将涂层材料预成膜到平坦的表面上来实现更精细的雾化喷雾液滴尺寸，这提高了制造重复性，降低了涂层方差，以及 增加治疗剂量可预测性。 在本发明的某些实施方案中，涂层材料包括治疗剂和生物活性材料。
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公开(公告)号：US20250115073A1
公开(公告)日：2025-04-10
申请号：US18933152
申请日：2024-10-31
Applicant: Tim O'Connor
Inventor： Tim O'Connor
Abstract: A storage board system including a singular, or a set of, corrugated backing members, composed of at least one write erasable outer surface, at least two vertically disposed parallel members mounted to the one, or a set of corrugated backing members, two or more horizontally disposed parallel members mounted in a perpendicular manner to the at least two vertically disposed parallel panels. The horizontally disposed parallel members comprise two or more sets of parallel members attached by a set of two perpendicular joinder members which define a linked set of rectangular areas so as to form a rectangular corrugation. One, or a series of removably attached, multi-purpose, multi-directional hanging devices disposed for attachment to the at least two horizontally disposed corrugated parallel panels including a larger first U-shaped member and a second side comprising a smaller second U-shaped member used in tandem with a self-attaching removably attached bin.
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公开(公告)号：US20240279914A1
公开(公告)日：2024-08-22
申请号：US18648559
申请日：2024-04-29
Applicant: Tim O'Connor , Shawn Stapp
Inventor： Tim O'Connor , Shawn Stapp
CPC classification number: E03C1/0403 , F16K19/006
Abstract: A mixing valve adapter is disclosed to connect water lines from a mixing valve to a sink faucet. An example of the mixing valve adapter includes an adapter body for connection between the mixing valve and the sink faucet. Valve connections of the adapter body connect to the respective water source connections and the mixing valve. Faucet connections on the adapter body connect to the sink faucet. The faucet connections have reinforcement structures. One of the valve connections also has a reinforcement structure. Connection housings connect the faucet connections to the sink faucet.
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公开(公告)号：US20230003326A1
公开(公告)日：2023-01-05
申请号：US17809186
申请日：2022-06-27
Applicant: Tim O'Connor , Shawn Stapp
Inventor： Tim O'Connor , Shawn Stapp
IPC: F16L41/03
Abstract: A mixing valve adapter is disclosed for a sink faucet with a mixing valve. An example mixing valve adapter includes an adapter body formed as a rigid unitary structure that does not flex so that the mixing valve is mounted rigid to the sink faucet without separately mounting the mixing valve apart from the sink faucet. The example mixing valve adapter also includes a first valve connection on the adapter body for connecting mixed cold and hot water from the mixing valve, and a first faucet connection on the adapter body for connecting the mixed cold and hot water to the sink faucet. The example mixing valve adapter also includes a second valve connection on the adapter body for connecting cold water from the mixing valve, and a second faucet connection on the adapter body for connecting the cold water to the sink faucet.
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