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公开(公告)号：US08398693B2
公开(公告)日：2013-03-19
申请号：US10763825
申请日：2004-01-23
申请人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
发明人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/1214 , A61B17/320725 , A61B2017/00398 , A61B2017/00871 , A61B2017/22061 , A61F2/962 , A61M25/0054 , A61M25/0158 , A61M2025/0058 , A61N1/20
摘要： The present invention relates to medical devices for implantation or insertion into body lumens, for example, catheters, guidewires, stents and aneurysm coils. The devices of the present invention comprise electrically actuated materials, such as electroactive polymers and piezoelectric and electrostrictive materials, which enhance or expand their functionality.
摘要翻译： 本发明涉及用于植入或插入体腔的医疗装置，例如导管，导线，支架和动脉瘤线圈。 本发明的装置包括电致动材料，例如电活性聚合物和压电和电致伸缩材料，其增强或扩大它们的功能。
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12.发明授权Medical devices employing conductive polymers for delivery of therapeutic agents 有权使用导电聚合物递送治疗剂的医疗装置公开(公告)号：US08275455B2
公开(公告)日：2012-09-25
申请号：US12487203
申请日：2009-06-18
IPC分类号： A61N1/30
CPC分类号： A61M25/1029 , A61F2002/0081 , A61F2250/0068 , A61K9/0009 , A61K31/00 , A61K31/337 , A61K31/4745 , A61K31/52 , A61L27/50 , A61L27/54 , A61L29/14 , A61L29/16 , A61L2300/416 , A61L2300/602 , A61M25/10 , A61M25/104 , A61M2025/0057 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1086 , A61M2025/1088 , A61M2025/1093
摘要： In accordance with one aspect, the invention relates to medical devices which comprise at least one reservoir, a therapeutic-agent-containing region disposed within the reservoir and an electrode comprising a conductive polymer. The devices of the invention are configured such that a rate of release of the therapeutic agent from the reservoir changes upon a change in the oxidation state of the conductive polymer.
摘要翻译： 根据一个方面，本发明涉及包括至少一个贮存器，设置在储存器内的含治疗剂的区域和包含导电聚合物的电极的医疗装置。 本发明的装置被配置成使得治疗剂从贮存器释放的速率随着导电聚合物的氧化态的变化而变化。
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13.发明申请Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面公开(公告)号：US20110282433A1
公开(公告)日：2011-11-17
申请号：US13189152
申请日：2011-07-22
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
IPC分类号： A61F2/84
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译： 本发明涉及减少治疗剂从支架分层的机制和方法。 这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。
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公开(公告)号：US07963940B2
公开(公告)日：2011-06-21
申请号：US11208879
申请日：2005-08-22
申请人： Thomas J. Holman , Jan Weber , Tracee Eidenschink
发明人： Thomas J. Holman , Jan Weber , Tracee Eidenschink
IPC分类号： A61M29/00
CPC分类号： A61F7/12 , A61F2007/0063 , A61F2007/126
摘要： A device for providing a fluid to a target tissue region of a body vessel is described. The device includes an elongate member having a lumen to receive a fluid, and a structure deployable from a distal portion of the elongate member to channel blood flowing in the vessel. Also described are a method of, and a system for, providing a fluid to a target tissue region inside a body.
摘要翻译： 描述了一种用于向身体血管的靶组织区域提供流体的装置。 该装置包括具有用于容纳流体的内腔的细长构件，以及可从细长构件的远侧部分展开以使在血管中流动的血液通道的结构。 还描述了向身体内的靶组织区域提供流体的方法和系统。
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公开(公告)号：US07886569B2
公开(公告)日：2011-02-15
申请号：US12510807
申请日：2009-07-28
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
CPC分类号： A61F2/958 , A61F2002/9522 , B25B27/10 , Y10T29/49913 , Y10T29/49925 , Y10T29/53065 , Y10T29/53652 , Y10T29/53987 , Y10T29/53996
摘要： In one embodiment, an apparatus for shaping an article may comprise a plurality of movable dies arranged to form a chamber whose size may be varied by moving the dies. Each of the dies may have a contacting surface for contacting the article to be shaped. The chamber may have a first portion having a first cross-section and a second portion having a second cross-section. Either portion may include a taper. The first portion may have a differently shaped cross-section than the second portion. The first portion may have a cross-section of greater area than the second portion. The longitudinal axis of the first portion may be offset from the longitudinal axis of the second portion.
摘要翻译： 在一个实施例中，用于成型物品的装置可以包括多个可移动模具，其被设置成形成其尺寸可以通过移动模具而改变的腔室。 每个模具可以具有用于接触待成形制品的接触表面。 腔室可以具有第一部分和第二部分，第一部分具有第一横截面，第二部分具有第二横截面。 任一部分可以包括锥形。 第一部分可以具有与第二部分不同的形状的横截面。 第一部分可以具有比第二部分更大的面积的横截面。 第一部分的纵向轴线可以偏离第二部分的纵向轴线。
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公开(公告)号：US20080161900A1
公开(公告)日：2008-07-03
申请号：US11763740
申请日：2007-06-15
申请人： Jan Weber , Thomas J. Holman , Tracee Eidenschink
发明人： Jan Weber , Thomas J. Holman , Tracee Eidenschink
CPC分类号： A61F2/013 , A61F2/06 , A61F2/82 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/003
摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes an elongated hollow body formed of a polymeric matrix containing one or more regions of a pre-determined weight percent of carbon nanotubes in general alignment in a pre-determined orientation. The medical device can have a compressed state with a first transverse dimension and an expanded state with a second relatively greater transverse dimension.
摘要翻译： 描述医疗装置，例如内用假体，以及制造装置的方法。 在一些实施方案中，医疗装置包括由聚合物基质形成的细长中空体，其含有预定重量百分比的碳纳米管的一个或多个区域，以预定方向大致对准。 医疗装置可以具有第一横向尺寸的压缩状态和具有第二较大横向尺寸的膨胀状态。
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公开(公告)号：US20080119923A1
公开(公告)日：2008-05-22
申请号：US12011082
申请日：2008-01-23
申请人： Thomas Tran , Tracee Eidenschink , Jan Weber
发明人： Thomas Tran , Tracee Eidenschink , Jan Weber
IPC分类号： A61F2/06
CPC分类号： A61F2/954 , A61F2/856 , A61F2/958 , A61F2002/30014 , A61F2002/30199 , A61F2002/30326 , A61F2002/3068 , A61F2002/826 , A61F2002/9583 , A61F2210/0076 , A61F2230/0063 , A61F2250/0018 , A61F2250/0037 , A61F2250/0068
摘要： A stent delivery system comprises a catheter which includes a catheter shaft and a balloon positioned thereon. A rotatable sheath is rotatably disposed about a portion of the catheter. The rotatable sheath has a distal portion which extends over the balloon and a proximal portion which extends over the catheter shaft proximal to the balloon. A stent prior to delivery is disposed about the distal portion. The rotatable sheath may also and/or alternatively be constructed of a non-compliant material where as the balloon is a compliant material.
摘要翻译： 支架输送系统包括导管，其包括导管轴和定位在其上的气囊。 可旋转护套围绕导管的一部分可旋转地设置。 可旋转护套具有在气囊上延伸的远侧部分和在导管轴上靠近气囊延伸的近端部分。 输送前的支架围绕远侧部分设置。 可旋转护套还可以和/或替代地由不顺应性材料构成，其中气囊是顺应性材料。
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公开(公告)号：US07207204B2
公开(公告)日：2007-04-24
申请号：US10788088
申请日：2004-02-26
申请人： Jan Weber , Tracee Eidenschink
发明人： Jan Weber , Tracee Eidenschink
CPC分类号： A61F2/958 , A61F2002/9522 , B25B27/10 , Y10T29/49913 , Y10T29/49925 , Y10T29/53065 , Y10T29/53652 , Y10T29/53987 , Y10T29/53996
摘要： In one embodiment, an apparatus for shaping an article may comprise a plurality of movable dies arranged to form a chamber whose size may be varied by moving the dies. Each of the dies may have a contacting surface for contacting the article to be shaped. The chamber may have a first portion having a first cross-section and a second portion having a second cross-section. Either portion may include a taper. The first portion may have a differently shaped cross-section than the second portion. The first portion may have a cross-section of greater area than the second portion. The longitudinal axis of the first portion may be offset from the longitudinal axis of the second portion.
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公开(公告)号：US20050165439A1
公开(公告)日：2005-07-28
申请号：US10763825
申请日：2004-01-23
申请人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
发明人： Jan Weber , Tracee Eidenschink , David Elizondo , Loren Simer
CPC分类号： A61F2/958 , A61B17/1214 , A61B17/320725 , A61B2017/00398 , A61B2017/00871 , A61B2017/22061 , A61F2/962 , A61M25/0054 , A61M25/0158 , A61M2025/0058 , A61N1/20
摘要： The present invention relates to medical devices for implantation or insertion into body lumens, for example, catheters, guidewires, stents and aneurysm coils. The devices of the present invention comprise electrically actuated materials, such as electroactive polymers and piezoelectric and electrostrictive materials, which enhance or expand their functionality.
摘要翻译： 本发明涉及用于植入或插入体腔的医疗装置，例如导管，导线，支架和动脉瘤线圈。 本发明的装置包括电致动材料，例如电活性聚合物和压电和电致伸缩材料，其增强或扩大它们的功能。
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公开(公告)号：US09011516B2
公开(公告)日：2015-04-21
申请号：US11763740
申请日：2007-06-15
申请人： Jan Weber , Thomas J. Holman , Tracee Eidenschink
发明人： Jan Weber , Thomas J. Holman , Tracee Eidenschink
CPC分类号： A61F2/013 , A61F2/06 , A61F2/82 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/003
摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes an elongated hollow body formed of a polymeric matrix containing one or more regions of a pre-determined weight percent of carbon nanotubes in general alignment in a pre-determined orientation. The medical device can have a compressed state with a first transverse dimension and an expanded state with a second relatively greater transverse dimension.
摘要翻译： 描述医疗装置，例如内用假体，以及制造装置的方法。 在一些实施方案中，医疗装置包括由聚合物基质形成的细长中空体，其含有预定重量百分比的碳纳米管的一个或多个区域，以预定方向大致对准。 医疗装置可以具有第一横向尺寸的压缩状态和具有第二较大横向尺寸的膨胀状态。
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