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116 条记录 (耗时 0.03 秒)

    Local perfusion device
    1.
    发明授权
    Local perfusion device 有权
    局部灌注装置

    公开(公告)号：US07963940B2

    公开(公告)日：2011-06-21

    申请号：US11208879

    申请日：2005-08-22

    申请人： Thomas J. Holman ,  Jan Weber ,  Tracee Eidenschink

    发明人： Thomas J. Holman ,  Jan Weber ,  Tracee Eidenschink

    IPC分类号： A61M29/00

    CPC分类号： A61F7/12 ,  A61F2007/0063 ,  A61F2007/126

    摘要： A device for providing a fluid to a target tissue region of a body vessel is described. The device includes an elongate member having a lumen to receive a fluid, and a structure deployable from a distal portion of the elongate member to channel blood flowing in the vessel. Also described are a method of, and a system for, providing a fluid to a target tissue region inside a body.

    摘要翻译： 描述了一种用于向身体血管的靶组织区域提供流体的装置。 该装置包括具有用于容纳流体的内腔的细长构件，以及可从细长构件的远侧部分展开以使在血管中流动的血液通道的结构。 还描述了向身体内的靶组织区域提供流体的方法和系统。

    Rotatable sheath, assembly and method of manufacture of same
    6.
    发明授权
    Rotatable sheath, assembly and method of manufacture of same 有权
    可旋转护套，组装及其制造方法

    公开(公告)号：US07691137B2

    公开(公告)日：2010-04-06

    申请号：US10952007

    申请日：2004-09-28

    申请人： Thomas J. Holman ,  Tracee Eidenschink

    发明人： Thomas J. Holman ,  Tracee Eidenschink

    IPC分类号： A61F2/84

    CPC分类号： A61M25/10 ,  A61F2/958 ,  A61M25/0009 ,  A61M25/0045 ,  A61M2025/1056 ,  A61M2025/1081

    摘要： A medical device comprises a catheter having a catheter shaft and a medical balloon positioned thereon, as well as a rotatable assembly disposed about the balloon. The balloon has a pre-expansion state and an expanded state. The rotatable assembly comprises a sheath, wherein the sheath is disposed about the balloon in both the pre-expansion state and in the expanded state. The sheath is rotatable about the balloon in the pre-expansion state. The sheath comprises an inner layer and an outer layer, the inner layer is in rotatable contact with the balloon and the outer layer is disposed about the inner layer. The inner layer is at least partially constructed of at least one material having a durometer value greater than that of the outer layer.

    摘要翻译： 医疗装置包括具有定位在其上的导管轴和医用气囊的导管，以及围绕气囊设置的可旋转组件。 气球具有预膨胀状态和膨胀状态。 可旋转组件包括护套，其中护套围绕球囊设置在预膨胀状态和膨胀状态。 护套可以在预膨胀状态下围绕气球旋转。 护套包括内层和外层，内层可与气球旋转接触，外层围绕内层设置。 内层至少部分由至少一种硬度值大于外层的材料构成。

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    8.
    发明申请
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 有权
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US20080262412A1

    公开(公告)日：2008-10-23

    申请号：US12077603

    申请日：2008-03-20

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61N1/30 ,  A61M25/10

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。