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    Proteins and Uses
    11.
    发明申请
    Proteins and Uses 有权

    公开(公告)号：US20210301012A1

    公开(公告)日：2021-09-30

    申请号：US16342800

    申请日：2017-10-23

    Applicant: UCB Biopharma SPRL

    Inventor： Michael John Wright ,  Ralph Adams ,  Rebecca Burnley ,  Anna Ettorre

    IPC: C07K16/24

    Abstract: The invention is in the field of protein:protein interactions, in particular the stabilisation of protein:protein interactions. Binding proteins are provided for stabilising the interactions, together with compositions comprising the binding proteins. Methods using the binding proteins are also provided, including targeting of cells and also medical uses.

    Albumin binding antibodies and binding fragments thereof
    17.
    发明授权
    Albumin binding antibodies and binding fragments thereof 有权

    公开(公告)号：US10023631B2

    公开(公告)日：2018-07-17

    申请号：US15795874

    申请日：2017-10-27

    Applicant: UCB Biopharma SPRL

    Inventor： Ralph Adams ,  Pallavi Bhatta ,  Sam Philip Heywood ,  David Paul Humphreys

    IPC: C07K16/18 ,  C07K16/28

    Abstract: A serum albumin binding antibody or fragment thereof comprising a heavy chain variable domain having the sequence given in SEQ ID NO: 1 or SEQ ID NO:2 and/or comprising a light chain variable domain having the sequence given in SEQ ID NO:3 or SEQ ID NO:4, in particular comprising a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 1 and SEQ ID NO:3 or a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 2 and SEQ ID NO:4. The disclosure also extends to polynucleotides encoding the antibodies or fragments, vectors comprising same and host cells capable of expressing the polynucleotides. The disclosure further includes pharmaceutical compositions comprising the antibodies or fragments and therapeutic used of any one of the same.

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