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公开(公告)号：US2554986A
公开(公告)日：1951-05-29
申请号：US13703750
申请日：1950-01-05
Applicant: UPJOHN CO
Inventor： HEYL FREDERICK W , HERR MILTON E
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公开(公告)号：US3649453A
公开(公告)日：1972-03-14
申请号：US3649453D
申请日：1970-01-21
Applicant: UPJOHN CO
Inventor： HERR MILTON E , MURRAY HERBERT C , FONKEN GUNTHER S
IPC: C07C233/02
CPC classification number: C07C233/02 , Y10S435/911 , Y10S435/939
Abstract: A NOVEL METHOD FOR THE INTRODUCTION OF OXYGEN INTO 1-AMINOADAMANTANES BY BICONVERSION BY MEANS OF SPOROTRICHUM SULFURESCENS, RHIZOPUS ARRHIZUS OR CURVULARIA LUNATA TO OBTAIN THE CORRESPONDING OXYGENATED 1AMIDOANDAMANTANES WHICH CAN BE CHEMICALLY CONVERTED TO NOVEL DERIVATIVES THEREOF. THESE NOVEL BIOCONVERSION PRODUCTS AND THEIR DERIVATIVES ARE OF PARTICULAR VALUE AS CENTRAL NERVOUS SYSTEM STIMULANTS.
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13.发明授权Method for microbioligical introduction of oxygen into heterocyclic nitrogen compounds 失效将氧化物引入杂环氮化合物中的微生物导入方法
公开(公告)号：US3556943A
公开(公告)日：1971-01-19
申请号：US3556943D
申请日：1967-09-11
Applicant: UPJOHN CO
Inventor： FONKEN GUNTHER S , HERR MILTON E , MURRAY HERBERT C
IPC: C07D211/16 , C07D211/22 , C07D211/32 , C07D211/42 , C07D211/46 , C07D211/48 , C07D211/74 , C07D221/22 , C07D295/10 , C07D295/18 , C07D295/182 , C07D295/192 , C07D295/205 , C07D295/22 , C07D295/26 , C07D453/06 , C07D491/10 , C12P17/10 , C12D13/00
CPC classification number: C07D221/22 , C07D211/16 , C07D211/22 , C07D211/32 , C07D211/42 , C07D211/46 , C07D211/48 , C07D211/74 , C07D295/10 , C07D295/18 , C07D295/182 , C07D295/192 , C07D295/205 , C07D295/22 , C07D295/26 , C07D453/06 , C07D491/10 , C12P17/10 , Y10S435/911
Abstract: A METHOD FOR THE MOCROBIOLOGICAL INTRODUCTION OF OXYGEN INTO THE HETEROCYCLIC RING OF N-ACYL DERIVATIVES OF POLYMETHYLENEIMINES (AZACYLOZLKANES) AND AZABICYCLOALKANES USING SPOROTRICHUM SULFURESCENS TO OBTAIN THE CORRESPONDING OXYGENATED PRODUCTS.
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公开(公告)号：US3016387A
公开(公告)日：1962-01-09
申请号：US84257059
申请日：1959-09-28
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , ALLAN CAMPBELL J , HERR MILTON E , HOGG JOHN A , PEDERSON RAYMOND L
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15.发明授权6-alpha methyl 17 alkyl 9alpha fluoro 11 oxygenated 17beta hydroxy-4-androsten-3-one compounds and process 失效6-α甲基17烷基9α氟11氧化17β羟基-4-雄甾-3-酮化合物和方法
公开(公告)号：US2842573A
公开(公告)日：1958-07-08
申请号：US69112357
申请日：1957-10-21
Applicant: UPJOHN CO
Inventor： HERR MILTON E , SPERO GEORGE B
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Patent Agency Ranking
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17.发明授权9alpha-halo-11beta, 17beta-dihydroxy-17alpha-methylandrostane-3-ones 失效9α-卤代-11beta，17β-二羟基-17α-甲基雄甾烷-3-酮
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公开(公告)号：US2773072A
公开(公告)日：1956-12-04
申请号：US36240453
申请日：1953-06-17
Applicant: UPJOHN CO
Inventor： HERR MILTON E , HEYL FREDERICK W
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公开(公告)号：US2647909A
公开(公告)日：1953-08-04
申请号：US17047050
申请日：1950-06-26
Applicant: UPJOHN CO
Inventor： HEYL FREDERICK W , HERR MILTON E
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20.发明授权Nu-cycloalkyl-azabicyclooctanes and-nonanes and nu-(2-cycloalken-1-yl)-azabicyclooctane and -nonane intermediates 失效N-环烷基 - 氮杂双环辛烷和壬烷和nu-（2-环烯烃-1-基） - 氮杂双环辛烷和壬烷中间体
公开(公告)号：US3385846A
公开(公告)日：1968-05-28
申请号：US53032366
申请日：1966-02-28
Applicant: UPJOHN CO
Inventor： HERR MILTON E , MOFFETT ROBERT B
IPC: A61K31/00 , C07D295/02 , C07D295/033 , C07D453/06
CPC classification number: C07D453/06 , A61K31/00 , C07D295/033
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