公开(公告)号：US10385995B2

公开(公告)日：2019-08-20

申请号：US14651835

申请日：2013-12-16

Applicant: Waters Technologies Corporation

Inventor： Sylvain Cormier ,  Joshua A. Shreve ,  Joseph A. Luongo ,  Paul Keenan ,  Kenneth Plant

IPC: G01N30/22 ,  F16L19/02 ,  G01N30/60

Abstract: Described is a coupling seal that includes a polymeric body having a bore extending from a first end to an internal sealing surface and a fluid channel extending from the internal sealing surface to a second end. The bore is configured to receive a tube having a fluid channel so that an endface of the tube engages the internal sealing surface. The second end of the polymeric body is configured to contact a sealing surface of a coupling body that has a fluid channel extending from the sealing surface. A fluidic seal occurs when the coupling seal is compressed between the endface and the sealing surface. A void between an outer surface of the polymeric body and an inner surface of the coupling body receives the deformation of the coupling seal while under compression to thereby prevent the fluid channel of the tube from being crushed or obstructed.

公开(公告)号：US10238989B2

公开(公告)日：2019-03-26

申请号：US14364148

申请日：2012-12-07

Applicant: Waters Technologies Corporation

Inventor： Joseph A. Luongo ,  Craig Hamilton Dobbs

IPC: B01D15/14 ,  G01N30/34 ,  B01D15/16 ,  G01N30/20 ,  G01N30/38

Abstract: A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.

公开(公告)号：US20150129474A1

公开(公告)日：2015-05-14

申请号：US14406279

申请日：2013-06-26

Applicant: Waters Technologies Corporation

Inventor： Edouard S.P. Bouvier ,  Pamela C. Iraneta ,  Joseph A. Luongo ,  Joseph A. Jarrell

IPC: B01D15/22

CPC classification number: B01D15/22 ,  B01D15/161 ,  B01D15/20 ,  G01N30/30 ,  G01N30/54 ,  G01N30/88 ,  G01N2030/027 ,  G01N2030/3007 ,  G01N2030/3015 ,  G01N2030/3038 ,  G01N2030/3046 ,  G01N2030/3061 ,  G01N2030/3084 ,  G01N2030/889 ,  Y10T29/49826

Abstract: An apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column wherein the insulating member is formed from a vacuum chamber surrounding the chromatography column. Another apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column, wherein the insulating member includes aerogel. Also described is a method of insulating a chromatography column comprising forming a jacket surrounding the chromatography column, and creating a vacuum chamber in an area between the jacket and the chromatography column.

Abstract translation: 用于进行液相色谱的装置包括层析柱和围绕色谱柱的绝缘构件，其中绝缘构件由围绕色谱柱的真空室形成。 用于进行液相色谱的另一种装置包括层析柱和围绕色谱柱的绝缘构件，其中绝缘构件包括气凝胶。 还描述了一种隔离色谱柱的方法，包括形成围绕色谱柱的夹套，并在夹套和色谱柱之间的区域中形成真空室。