公开(公告)号：US20110160221A1

公开(公告)日：2011-06-30

申请号：US12667850

申请日：2008-07-03

Applicant: Josef R. Bencsik ,  James F. Blake ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Christine Chabot ,  Jun Liang ,  Brian S. Safina

Inventor： Josef R. Bencsik ,  James F. Blake ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Christine Chabot ,  Jun Liang ,  Brian S. Safina

IPC: A61K31/497 ,  C07D239/70 ,  A61P35/00

CPC classification number: C07D239/70 ,  C07D401/12 ,  C07D403/12 ,  C07D409/12

Abstract: The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract translation: 本发明提供了式I化合物，包括互变异构体，拆分的对映异构体，非对映异构体，溶剂合物，代谢物，盐和药学上可接受的前药。 还提供了使用本发明化合物作为AKT蛋白激酶抑制剂和治疗过度增殖性疾病如癌症的方法。

公开(公告)号：US20110136013A1

公开(公告)日：2011-06-09

申请号：US12591961

申请日：2009-12-07

Applicant: Na Liu ,  Meng-Yao Wu ,  Lei-Min Xu ,  Lu Li ,  Rui Xu ,  Feng-Gang Zhao

Inventor： Na Liu ,  Meng-Yao Wu ,  Lei-Min Xu ,  Lu Li ,  Rui Xu ,  Feng-Gang Zhao

IPC: H01M4/58 ,  B05D5/12 ,  C01G25/02 ,  C01G19/02 ,  C01F7/02 ,  C01F5/02 ,  C01B33/12 ,  C01F17/00 ,  C01G9/02

CPC classification number: H01M10/0525 ,  H01M4/0471 ,  H01M4/131 ,  H01M4/1391 ,  H01M4/485 ,  H01M4/505 ,  H01M4/525

Abstract: A method is disclosed for coating a positive active material of a lithium-ion battery. The method includes the step of dissolving at least one salt that contains a coating metal in a solvent to provide a solution, the step of dissolving a lithium-containing positive active material in the solution and adjusting the pH value of the solution to deposit M(OH)2n on the lithium-containing positive active material, the step of drying the M(OH)2n and the lithium-containing positive active material, and the step of sintering the M(OH)2n and the lithium-containing positive active material to coat the lithium-containing positive active material with MOn.

Abstract translation: 公开了一种涂覆锂离子电池的正极活性物质的方法。 该方法包括将含有涂层金属的至少一种盐溶解在溶剂中以提供溶液的步骤，将含锂正极活性物质溶解在溶液中并调节溶液的pH值以沉淀M（ OH）2 n，所述含有M（OH）2n和所述含锂正极活性物质的步骤，所述M（OH）2n和所述含锂正极活性物质的烧结工序 用MOn涂覆含锂正极活性物质。

公开(公告)号：US20110015204A1

公开(公告)日：2011-01-20

申请号：US12667848

申请日：2008-07-03

Applicant: Josef Bencsik ,  James F. Blake ,  James M. Graham ,  Martin F. Hentemann ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Stephen T. Schlachter ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Mike Welch ,  Jun Liang ,  Brian S. Safina

Inventor： Josef Bencsik ,  James F. Blake ,  James M. Graham ,  Martin F. Hentemann ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Stephen T. Schlachter ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Mike Welch ,  Jun Liang ,  Brian S. Safina

IPC: A61K31/497 ,  C07D239/70 ,  A61P35/00

CPC classification number: C07D403/12 ,  C07D401/12

Abstract: The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract translation: 本发明提供式（I）化合物，其包括互变异构体，拆分的对映异构体，非对映异构体，溶剂合物，代谢物，盐和药学上可接受的前药。 还提供了使用本发明化合物作为AKT蛋白激酶抑制剂和治疗过度增殖性疾病如癌症的方法。

公开(公告)号：US07226338B2

公开(公告)日：2007-06-05

申请号：US10917069

申请日：2004-08-12

Applicant: Rod Duncan ,  Joel Witt ,  Mark Quadling ,  Henley Quadling ,  Jeffrey Prince ,  Branko Bem ,  Rui Xu ,  Kirk Ray ,  Basil Haymann ,  Anthony Starfield

Inventor： Rod Duncan ,  Joel Witt ,  Mark Quadling ,  Henley Quadling ,  Jeffrey Prince ,  Branko Bem ,  Rui Xu ,  Kirk Ray ,  Basil Haymann ,  Anthony Starfield

IPC: B24B49/00 ,  B24B51/00

CPC classification number: A61C13/0009 ,  A61C13/0004 ,  Y10T409/30 ,  Y10T409/301792 ,  Y10T409/303976 ,  Y10T483/1733

Abstract: The improved milling machine makes use of individually controlled x-axis, y-axis, and z-axis carriages. These carriages provide positive and precise control of the position of the cutting tools and the blank to be cut. A tool changer allows the tools to be changed to accommodate other materials. A camera is used to detect wear on the tools.

Abstract translation: 改进的铣床使用单独控制的x轴，y轴和z轴支架。 这些托架可以对切割工具和要切割的坯料的位置提供正确和精确的控制。 刀具更换器允许更换工具以适应其他材料。 相机用于检测工具上的磨损。

公开(公告)号：US07091357B2

公开(公告)日：2006-08-15

申请号：US10328192

申请日：2002-12-26

Applicant: Peter A. Crooks ,  Linda Dwoshin ,  Rui Xu ,  Joshua T. Ayers

Inventor： Peter A. Crooks ,  Linda Dwoshin ,  Rui Xu ,  Joshua T. Ayers

IPC: C07D401/04

CPC classification number: C07D401/04

Abstract: Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, addiction to opiates, addiction to alcohol, addiction to tobacco products, addiction to nicotine, schizophrenia and related diseases, depression and related conditions, Alzheimer's disease, Parkinson's disease, irritable bowel syndrome, and colitis. The compounds competitively inhibit central nervous system acting nicotinic receptor agonists and act at the putative α3β2* and α4β2 neuronal nicotinic receptors in the central nervous system.

公开(公告)号：US06503922B2

公开(公告)日：2003-01-07

申请号：US09941926

申请日：2001-08-30

Applicant: Peter A. Crooks ,  Linda P. Dwoskin ,  Rui Xu ,  Vladimir P. Grinevich

Inventor： Peter A. Crooks ,  Linda P. Dwoskin ,  Rui Xu ,  Vladimir P. Grinevich

IPC: A61K314745

CPC classification number: C07D471/04

Abstract: Pharmaceutical compounds comprising bridged nicotine analogs of N-octylnicotinium iodide (NONI) having selective antagonist properties at &agr;3&bgr;2-containing nicotinic receptor subtypes, and compositions containing these compounds. The compounds and compositions are used to treat central nervous system pathologies.

公开(公告)号：US09149950B2

公开(公告)日：2015-10-06

申请号：US13376187

申请日：2011-11-03

Applicant: Huifang Duan ,  Shaoyuan Zhang ,  Hao Jin ,  Rui Xu ,  Junjie Huang

Inventor： Huifang Duan ,  Shaoyuan Zhang ,  Hao Jin ,  Rui Xu ,  Junjie Huang

IPC: A47L9/02 ,  B26D7/18 ,  B28D7/02 ,  G02F1/13

CPC classification number: B26D7/1863 ,  B28D7/02 ,  G02F1/1303

Abstract: The present invention discloses a debris collection device for cutting mechanism and an LCD panel cutting debris suction device. A debris collection device for cutting mechanism comprises a debris collection cap and a suction spray head used for connecting with a suction device; the debris collection cap comprises a connecting part used for surrounding and fixing on the cutting mechanism, and the debris collection cap is provided with a through hole communicated with the suction spray head. The present invention can remove the debris produced in the cutting process in time, and can reduce relevant defects such as line scratches, terminal scratches, short circuit, broken circuit, etc. which are generated because of debris. Thus, the product yield and quality of LCD panels can be improved, and the time of the subsequent cleaning process can be reduced.

Abstract translation: 本发明公开了一种用于切割机构的碎片收集装置和一个LCD面板切屑碎屑抽吸装置。 用于切割机构的碎片收集装置包括碎片收集盖和用于与抽吸装置连接的抽吸喷头; 碎屑收集帽包括用于围绕和固定在切割机构上的连接部分，并且碎屑收集帽设置有与吸入喷头连通的通孔。 本发明可以及时去除切割过程中产生的碎屑，并且可以减少由于碎屑而产生的相关缺陷，例如线划痕，端子划痕，短路，断路等。 因此，可以提高LCD面板的产品产量和质量，并且可以减少后续清洁处理的时间。

公开(公告)号：US20140346398A1

公开(公告)日：2014-11-27

申请号：US14363295

申请日：2012-05-02

Applicant: Rui Xu ,  Chongmin Mei ,  Fayuan Wu ,  Yongqiang Deng ,  Rongjun Mao ,  Xu Tian

Inventor： Rui Xu ,  Chongmin Mei ,  Fayuan Wu ,  Yongqiang Deng ,  Rongjun Mao ,  Xu Tian

IPC: B01D53/50

CPC classification number: B01D53/502 ,  B01D2251/404 ,  B01D2251/606

Abstract: A wet limestone flue gas desulfurization slurry stabilizer and a method for using the same are disclosed. The stabilizer consists of lime, sodium formate and an antifoaming agent, the components and mass percentages thereof are as follows: lime, 30% to 70%, sodium formate, 15% to 40%, the antifoaming agent, 15% to 40%. The method for using the desulfurization slurry stabilizer comprises: preparing the slurry stabilizer into a homogeneous liquid having a mass concentration of 10% to 30% with water or desulfurization slurry outside a desulfurization tower, and spraying the homogeneous liquid into the absorption area and the reaction area of the desulfurization tower using a pump and a slurry atomizing and spraying device.

Abstract translation: 公开了一种湿灰石烟气脱硫浆料稳定剂及其使用方法。 稳定剂由石灰，甲酸钠和消泡剂组成，其组分和质量百分比如下：石灰，30％至70％，甲酸钠，15％至40％，消泡剂，15％至40％。 使用脱硫浆料稳定剂的方法包括：使用脱水塔外部的水或脱硫浆料将浆料稳定剂制备成质量浓度为10％至30％的均匀液体，并将均匀的液体喷射到吸收区域和反应 使用泵和浆料雾化喷涂装置的脱硫塔面积。

公开(公告)号：US08865726B2

公开(公告)日：2014-10-21

申请号：US13393767

申请日：2010-09-03

Applicant: Steven W. Andrews ,  Kevin Ronald Condroski ,  Lisa A. De Meese ,  Jay Bradford Fell ,  John P. Fischer ,  John A. Josey ,  Kevin Koch ,  Yvan Le Huerou ,  Gregory F. Miknis ,  Martha E. Rodriguez ,  George T. Topalov ,  Eli M. Wallace ,  Rui Xu

Inventor： Steven W. Andrews ,  Kevin Ronald Condroski ,  Lisa A. De Meese ,  Jay Bradford Fell ,  John P. Fischer ,  John A. Josey ,  Kevin Koch ,  Yvan Le Huerou ,  Gregory F. Miknis ,  Martha E. Rodriguez ,  George T. Topalov ,  Eli M. Wallace ,  Rui Xu

IPC: C07D487/04 ,  A61K31/519 ,  A61P35/00

CPC classification number: C07D487/04

Abstract: Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.

Abstract translation: 式I化合物及其盐，其中R 1，R 2，R 2a，R 3，n，X和环B具有本说明书中给出的含义，是mTOR的抑制剂，可用于治疗对抑制作用敏感的疾病 mTOR，如癌症。

公开(公告)号：US08853216B2

公开(公告)日：2014-10-07

申请号：US12811983

申请日：2009-01-09

Applicant: Josef Bencsik ,  James F. Blake ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Christine Chabot ,  Steven Do ,  Jun Liang ,  Brian Safina ,  Birong Zhang ,  James Graham

Inventor： Josef Bencsik ,  James F. Blake ,  Nicholas C. Kallan ,  Ian S. Mitchell ,  Keith L. Spencer ,  Dengming Xiao ,  Rui Xu ,  Christine Chabot ,  Steven Do ,  Jun Liang ,  Brian Safina ,  Birong Zhang ,  James Graham

IPC: C07D239/70 ,  A61K31/517 ,  A61P35/00 ,  A61P29/00 ,  A61P25/00 ,  A61P9/00 ,  A61P15/02 ,  A61P17/00

CPC classification number: C07D239/70

Abstract: The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I. Also provided are methods of using the compound of this invention as an AKT protein kinase inhibitor and for the treatment of hyperproliferative diseases such as cancer.

Abstract translation: 本发明提供了包含式I的化合物及其药学上可接受的盐。还提供了使用本发明化合物作为AKT蛋白激酶抑制剂和治疗过度增殖性疾病如癌症的方法。