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22 条记录 (耗时 0.032 秒)

    Fluorescence station for biological sample testing machine
    11.
    发明授权
    Fluorescence station for biological sample testing machine 失效
    生物样品检测机荧光站

    公开(公告)号：US5925884A

    公开(公告)日：1999-07-20

    申请号：US799480

    申请日：1997-02-12

    申请人： Ron Robinson ,  David B. Shine ,  Craig Drager ,  Richard James Ryall ,  Erik William Anthon

    发明人： Ron Robinson ,  David B. Shine ,  Craig Drager ,  Richard James Ryall ,  Erik William Anthon

    IPC分类号： G01N21/27 ,  G01N21/64 ,  G01N35/00

    CPC分类号： G01N21/6452 ,  G01N21/276 ,  G01N21/6428 ,  G01N35/00029 ,  G01N2035/00049 ,  G01N2035/00099 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165

    摘要： A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slide the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.The fluorescence station has a linear flash lamp that illuminates a column of the wells of the cards simultaneously. A reference detector and dichromatic beam splitter design is used to insure that the fluorescence measurements are independent of lamp output changes over time. A solid reference is mounted to an optical shuttle and moved into the optical path to calibrate the fluorescence photodiode detectors.

    摘要翻译： 样本卡运送站将测试样本卡从卡的孵化站移动到样品测试机中的透射率和荧光光学站。 样品卡传送站具有传动带和相关的步进电机。 皮带从卡的一侧支持卡。 具有卡槽的凸缘设置在带上方。 卡片紧贴在卡槽内，并由传动带和传送带的滚筒从下方支撑。 当电机转动皮带时，皮带夹住卡，将卡沿插槽滑动到光学位置，皮带和卡之间不会发生任何滑动。 这种结构提供了对卡的移动的精确控制。 荧光站具有线性闪光灯，同时照亮卡的孔的列。 使用参考检测器和二色分束器设计来确保荧光测量与时间上的灯输出变化无关。 将固体参考安装到光梭上并移动到光路中以校准荧光光电二极管检测器。

    Specimen enclosure apparatus and containers and closure devices for the same
    16.
    发明申请
    Specimen enclosure apparatus and containers and closure devices for the same 审中-公开
    样品外壳装置和容器以及封闭装置相同

    公开(公告)号：US20070102393A1

    公开(公告)日：2007-05-10

    申请号：US11523306

    申请日：2006-09-19

    申请人： Bruno Colin ,  Sylvain Baeyaert ,  Chris Ronsick ,  Mark Wilson ,  Ron Robinson

    发明人： Bruno Colin ,  Sylvain Baeyaert ,  Chris Ronsick ,  Mark Wilson ,  Ron Robinson

    IPC分类号： B65D51/00 ,  B65D39/00

    CPC分类号： B65D51/241 ,  B01L3/50825 ,  B01L2300/042 ,  B01L2300/048 ,  B01L2300/049 ,  B65D39/0005 ,  B65D41/16 ,  B65D45/322

    摘要： Embodiments of the present invention include a specimen enclosure apparatus. The specimen enclosure apparatus includes a container having a cavity configured to receive the specimen and an opening extending through a neck of the container to the cavity. An internal flange is positioned intermediate the neck of the container. The specimen enclosure apparatus further includes a closure device configured to be received in the opening. The closure device has a flange seal portion configured to contact the internal flange to form a flange seal proximate the cavity and further has a radial travel limiter integrally formed with the closure device that is configured to contact the container in the opening to limit radial movement of the flange seal portion relative to the internal flange. Containers and closure devices are also provided.

    摘要翻译： 本发明的实施例包括一个样本封闭装置。 样本封闭装置包括容器，该容器具有构造成容纳样本的空腔和延伸穿过容器的颈部到空腔的开口。 内部法兰定位在容器颈部的中间。 样品外壳设备还包括被配置为容纳在开口中的封闭装置。 闭合装置具有法兰密封部分，其被构造成接触内部凸缘以形成靠近空腔的凸缘密封件，并且还具有与封闭装置一体形成的径向移动限制器，其构造成在开口中接触容器以限制径向运动 凸缘密封部分相对于内部凸缘。 还提供容器和封闭装置。

    Cutting and sealing station for test sample cards in an automated analytical system
    18.
    发明授权
    Cutting and sealing station for test sample cards in an automated analytical system 失效
    自动分析系统中测试样品卡的切割和封口站

    公开(公告)号：US5891396A

    公开(公告)日：1999-04-06

    申请号：US6617

    申请日：1998-01-13

    申请人： Clifford W. Karl ,  Ron Robinson

    发明人： Clifford W. Karl ,  Ron Robinson

    IPC分类号： B01L3/00 ,  G01N1/38 ,  G01N35/00 ,  G01N35/02

    CPC分类号： B01L3/50 ,  G01N35/00029 ,  G01N1/38 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/00148 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/114998 ,  Y10T436/115831 ,  Y10T436/119163 ,  Y10T436/25625 ,  Y10T436/2575

    摘要： An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles. The test sample positioning system moves the tray to a cutting and sealing station and then to an incubation station and loads the cards one at a time into a carousel within the incubation station. A test card transport station transports the test cards from the incubation station to an optical reading station, where optical measurements (e.g., transmittance and/or fluorescence optical testing) is conducted on the wells of the card. When the card has been read, it is either moved back to the incubation station for additional incubation and reading or transferred to a card disposal system when the reading is complete.

    摘要翻译： 用于测试存储在测试卡中的样品的自动样品测试机。 该机器具有测试样品定位系统，用于在机器中的各个站之间移动包含多个测试样品卡和流体容器的托盘。 该机器具有用于根据需要向容器添加预定量的稀释剂的稀释站。 移液站将流体从一个容器传送到另一个容器。 设置真空站，其具有可在上位置和下​​位置之间相对于托盘移动的真空室。 当室下降到较低位置时，室与托盘配合以与托盘的顶表面进行密封接合。 真空发生器为腔室提供真空。 当从室释放真空时，将流体样品从容器装载到卡中。 测试样品定位系统将托盘移动到切割和密封站，然后移动到孵化站，并将卡一次装载到孵育站内的转盘中。 测试卡传输站将测试卡从孵化站运送到光学读取站，其中在卡的孔上进行光学测量（例如，透射率和/或荧光光学测试）。 读卡完成后，将其移回孵化站进行额外的孵化和阅读，或者将其转移到卡片处理系统。

    Incubation station for test sample cards
    19.
    发明授权
    Incubation station for test sample cards 失效

    公开(公告)号：US5998201A

    公开(公告)日：1999-12-07

    申请号：US905374

    申请日：1997-08-04

    申请人： Gregory R. Maes ,  Dennis M. Connor ,  Brent D. Freiner ,  Clifford W. Karl ,  Ron Robinson ,  Raymond M. Shelton ,  Garry R. Tegeler ,  Michael James Justin

    发明人： Gregory R. Maes ,  Dennis M. Connor ,  Brent D. Freiner ,  Clifford W. Karl ,  Ron Robinson ,  Raymond M. Shelton ,  Garry R. Tegeler ,  Michael James Justin

    摘要： An incubation station has a carousel for receiving a plurality of test sample cards. An even temperature and air flow distribution inside the carousel and incubation of the cards over time at the proper temperature was found to be critically dependent upon air flow characteristics within the incubation station. To optimize air flow, the carousel was given an open rear side that is exposed to an air distribution table having a cover plate placed adjacent to the rear surface of the carousel. The cover plate has a plurality of elongate slots positioned in a symmetrical ring-shaped pattern in registry with the carousel. The elongate slots are positioned at an angle relative to the slots in the carousel such that each carousel slot receives air from more than one slot. An extra fan was also added to the system to increase the flow of air into the air table. Scallop features on the carousel walls also promote even distribution of air flow over the cards. The carousel may be divided into a plurality of carousel segments to increase ease of removal and insertion of the carousel into the incubation station and manufacturability of the carousel.