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公开(公告)号:US20230227581A1
公开(公告)日:2023-07-20
申请号:US17817334
申请日:2022-08-03
Applicant: Xencor, Inc.
Inventor: Rumana Rashid , Umesh S. Muchhal , Gregory Moore , Alex Nishtal , Seung Chu , Sung-Hyung Lee , Yoon Kyung Kim
CPC classification number: C07K16/40 , C07K16/2809 , C07K16/468 , C12N15/63 , C07K2317/565 , C07K2317/622
Abstract: The present invention is directed to antibodies, including novel antigen binding domains and heterodimeric antibodies, that bind Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3).
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公开(公告)号:US11225528B2
公开(公告)日:2022-01-18
申请号:US16354058
申请日:2019-03-14
Applicant: Xencor, Inc.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:US11225521B2
公开(公告)日:2022-01-18
申请号:US16393900
申请日:2019-04-24
Applicant: Xencor, Inc.
Inventor: Gregory Moore , Rumana Rashid , Sung-Hyung Lee , Paul Foster
Abstract: The present invention is directed to antibodies, including novel antigen binding domains and heterodimeric antibodies, that bind somatostatin receptor 2 (SSTR2).
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公开(公告)号:US11111315B2
公开(公告)日:2021-09-07
申请号:US15945681
申请日:2018-04-04
Applicant: Xencor, Inc.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:US20190248898A1
公开(公告)日:2019-08-15
申请号:US16393900
申请日:2019-04-24
Applicant: Xencor, Inc.
Inventor: Gregory Moore , Rumana Rashid , Sung-Hyung Lee , Paul Foster
CPC classification number: C07K16/2809 , A61K2039/505 , A61P35/00 , C07K16/2869 , C07K2317/31 , C07K2317/52 , C07K2317/53 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/64 , C07K2317/73
Abstract: The present invention is directed to antibodies, including novel antigen binding domains and heterodimeric antibodies, that bind somatostatin receptor 2 (SSTR2)
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公开(公告)号:US09856327B2
公开(公告)日:2018-01-02
申请号:US15186167
申请日:2016-06-17
Applicant: Xencor, Inc.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
CPC classification number: C07K16/468 , A61K2039/505 , C07K16/2809 , C07K16/2866 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K16/3061 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/64 , C07K2317/70 , C07K2317/73 , C07K2317/92 , C07K2317/94
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:US20160176969A1
公开(公告)日:2016-06-23
申请号:US14952705
申请日:2015-11-25
Applicant: XENCOR, INC.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Sung-Hyung Lee
CPC classification number: C07K16/2815 , A61K2039/505 , C07K16/22 , C07K16/2803 , C07K16/2809 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K16/40 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/60 , C07K2317/622 , C07K2317/73 , C07K2317/90 , C07K2317/94
Abstract: The invention provides bispecific antibodies that co-engage CD8 (preferably bivalently) and a target tumor antigen.
Abstract translation: 本发明提供了共参与CD8(优选二价))和靶肿瘤抗原的双特异性抗体。
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公开(公告)号:US11859011B2
公开(公告)日:2024-01-02
申请号:US17504452
申请日:2021-10-18
Applicant: Xencor, Inc.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
CPC classification number: C07K16/468 , C07K16/2809 , C07K16/2818 , C07K16/2896 , C07K16/30 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号:US11739144B2
公开(公告)日:2023-08-29
申请号:US17690702
申请日:2022-03-09
Applicant: Xencor, Inc.
Inventor: Matthew S. Faber , Sung-Hyung Lee , Yoon Kyung Kim , Jing Qi , Kendra N. Avery , Seung Y. Chu , Alex Nisthal , Matthew J. Bernett , John R. Desjarlais , Chad Borchert
CPC classification number: C07K16/28 , A61P35/00 , C07K16/2809 , C07K16/468 , C12N15/63
Abstract: Provided herein are novel CLDN6 binding domains, and anti-CLDN6×anti-CD3 antibodies that include such CLDN6 binding domains. Also provided herein are methods of using such antibodies for the treatment of CLDN6-associated cancers.
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公开(公告)号:US11673972B2
公开(公告)日:2023-06-13
申请号:US17124371
申请日:2020-12-16
Applicant: Xencor, Inc.
Inventor: Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
CPC classification number: C07K16/468 , C07K16/2809 , C07K16/2818 , C07K16/2896 , C07K16/30 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention is directed to novel heterodimeric antibodies.
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