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公开(公告)号：US12152076B2
公开(公告)日：2024-11-26
申请号：US17696799
申请日：2022-03-16
Applicant: Xencor, Inc.
Inventor： Matthew Bernett , Gregory Moore , John Desjarlais , Michael Hedvat , Christine Bonzon , Alex Nisthal , Umesh Muchhal
IPC: C07K16/28 , A61K39/395 , A61P35/00 , C07K16/46 , A61K39/00
Abstract: The present invention is directed to bispecific, heterodimeric checkpoint antibodies.
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公开(公告)号：US20220204624A1
公开(公告)日：2022-06-30
申请号：US17696799
申请日：2022-03-16
Applicant: Xencor, Inc.
Inventor： Matthew Bernett , Gregory Moore , John Desjarlais , Michael Hedvat , Christine Bonzon , Alex Nisthal , Umesh Muchhal
IPC: C07K16/28 , A61P35/00 , C07K16/46 , A61K39/395
Abstract: The present invention is directed to bispecific, heterodimeric checkpoint antibodies.
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公开(公告)号：US11225528B2
公开(公告)日：2022-01-18
申请号：US16354058
申请日：2019-03-14
Applicant: Xencor, Inc.
Inventor： Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号：US11111315B2
公开(公告)日：2021-09-07
申请号：US15945681
申请日：2018-04-04
Applicant: Xencor, Inc.
Inventor： Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号：US10752678B2
公开(公告)日：2020-08-25
申请号：US15943192
申请日：2018-04-02
Applicant: Allergan, Inc. , Xencor, Inc.
Inventor： Peter C. Baciu , Yanbin Liang , Jason Guu , Matthew Bernett , Umesh Muchhal , John Desjarlais
IPC: C07K16/18 , A61K39/395 , A61K39/00
Abstract: The present disclosure relates to antibodies and polynucleotides encoding the same, that may be used to prevent, control, or reduce the activity of the complement pathway. In addition, the disclosure is directed to compositions and methods for diagnosing and treating diseases mediated by or involving complement C5. Specifically, the disclosure is related to C5 antibodies.
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Patent Agency Ranking
公开(公告)号：US20180305465A1
公开(公告)日：2018-10-25
申请号：US15779325
申请日：2016-11-23
Applicant: AMGEN INC. , XENCOR, INC.
Inventor： Jennitte Leann Stevens , Mercedesz Balazs , Olivier Nolan-Stevaux , Gregory Moore , John Desjarlais , Matthew J. Bernett , Seung Y. Chu , Rumana Rashid , Umesh Muchhal
CPC classification number: C07K16/468 , A61K2039/505 , A61P35/00 , C07K16/2809 , C07K16/40 , C07K2317/31 , C07K2317/55 , C07K2317/622 , C07K2317/73 , C07K2317/92
Abstract: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.
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公开(公告)号：US20180222969A1
公开(公告)日：2018-08-09
申请号：US15943192
申请日：2018-04-02
Applicant: Allergan, Inc. , Xencor, Inc.
Inventor： Peter C. Baciu , Yanbin Liang , Jason Guu , Matthew Bernett , Umesh Muchhal , John Desjarlais
IPC: C07K16/18 , A61K39/00 , A61K39/395
Abstract: The present disclosure relates to antibodies and polynucleotides encoding the same, that may be used to prevent, control, or reduce the activity of the complement pathway. In addition, the disclosure is directed to compositions and methods for diagnosing and treating diseases mediated by or involving complement C5. Specifically, the disclosure is related to C5 antibodies.
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公开(公告)号：US09856327B2
公开(公告)日：2018-01-02
申请号：US15186167
申请日：2016-06-17
Applicant: Xencor, Inc.
Inventor： Matthew J. Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal , Sung-Hyung Lee
CPC classification number: C07K16/468 , A61K2039/505 , C07K16/2809 , C07K16/2866 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K16/3061 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/64 , C07K2317/70 , C07K2317/73 , C07K2317/92 , C07K2317/94
Abstract: The present invention is directed to novel heterodimeric antibodies.
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公开(公告)号：US12129309B2
公开(公告)日：2024-10-29
申请号：US17736475
申请日：2022-05-04
Applicant: Xencor, Inc.
Inventor： Matthew Bernett , Gregory Moore , John Desjarlais , Seung Chu , Rumana Rashid , Umesh Muchhal
CPC classification number: C07K16/40 , C07K16/18 , C07K16/2809 , C07K16/2896 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/92
Abstract: The present invention is directed to heterodimeric antibodies that bind CD3 and CD38.
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公开(公告)号：US20240279317A1
公开(公告)日：2024-08-22
申请号：US18414799
申请日：2024-01-17
Applicant: Allergan, Inc. , Xencor, Inc.
Inventor： Peter C. Baciu , Yanbin LIANG , Jason Guu , Matthew Bernett , Umesh Muchhal , John Desjarlais
IPC: C07K16/18 , A61K39/00 , A61K39/395
CPC classification number: C07K16/18 , A61K39/00 , A61K39/0005 , A61K39/3955 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
Abstract: The present disclosure relates to antibodies and polynucleotides encoding the same, that may be used to prevent, control, or reduce the activity of the complement pathway. In addition, the disclosure is directed to compositions and methods for diagnosing and treating diseases mediated by or involving complement C5. Specifically, the disclosure is related to C5 antibodies.
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