摘要:
With an object to seek parameters of a biological model corresponding to individual patents, the present invention provides a biological simulation system comprises an internal parameter set generating section which generates internal parameter sets constituting a biological model, a biological model computing section computing output of a biological model which emulates a biological response of a biological organ based on the generated internal parameter set, and a template database having a plurality of combinations of a reference output value of the biological model and an internal parameter set corresponding to the reference output value, wherein the internal parameter set generating section comprises a database referring means which selects a reference output approximate to an actual biological response from said template database and which selects an internal parameter set corresponding to the selected reference output value.
摘要:
A simulation system for simulating functions of biological organs, comprising a biological model in which the functions of the biological organs are expressed by mathematical models. The biological model comprises a hepatic metabolism model block having specified input and output relating to hepatic function for simulating the hepatic function. The system further comprises arithmetic means for calculating an output value by using measurable status variables of a liver based on input value to the hepatic metabolism model block.
摘要:
A non-invasive blood analyzer includes a light source unit for irradiating a portion of a living body, the portion including a blood vessel, and includes an image capturing unit for capturing an image of the irradiated portion. An analyzing unit is included for setting an analysis region in the captured image and analyzing a blood vessel portion in the set analysis region. The image capturing unit captures images of the irradiated portion of the living body a plurality of times and the analyzing unit specifies analysis regions including the same blood vessel portions with respect to the captured images. The analyzing unit determines these regions based upon a position of a feature in sequential images and calculates at least one of blood vessel width, blood component concentration and blood component concentration ratio with respect to the blood vessel portion in each specified analysis region.
摘要:
A treatment effect prediction system, comprising: a processor; and a memory, under control of the processor, including instructions enabling the processor to carry out operations comprising: determining a patient pathological condition information, which represents a feature of pathological condition of a patient, based on diagnostic data of the patient; accessing a database of stored pathological condition information and corresponding treatment effects occurring when predetermined treatment is provided; and retrieving, from the database, a specific treatment effect corresponding to the one of the stored pathological condition information that is similar to the patient pathological condition information, is disclosed. A treatment effect prediction method and a computer program product thereof are also disclosed.
摘要:
A simulation system for simulating a function of a biological organ using a biological model in which the function of the biological organ are represented by a mathematical model with a computer is provided. The present system receives input of time-series actual measurement data representing the biological response of a subject, estimates the biological response of the subject at a time point at which the measurement is not performed by using the input time-series actual measurement data, and generates time-series reference data representing the biological response of the subject. The present system further generates a virtual biological organ virtually constructed in a computer system using the times-series reference data. The virtual biological organ corresponds to the function of a biological organ of the subject.
摘要:
A diagnostic support system for diabetes including an input device used for inputting diagnostic data including clinical testing data; a biological model having parameters and which represents a organ function related to diabetes as a numerical model; an predicting means for predicting parameter values suited for a patient based on the diagnostic data and the biological model; a pathological condition analyzing means for analyzing a diabetic pathological condition of a patient based on the parameter values predicted by the predicting means; a diagnostic support information generating means for generating diagnostic support information based on the analyzed pathological condition; and a diagnostic support information outputting means for outputting information obtained by the diagnostic support information generating means. A computer-readable storage medium is also disclosed.
摘要:
To provide a gene examination method for predicting the onset risk of glaucoma based on the relation between a glaucoma-associated gene and the onset of glaucoma, the onset of glaucoma in future is predicted by using as an indication mutations in the gene region involving the code region and/or the upstream region of a glaucoma-associated gene. In the base sequence represented by SEQ ID NO:1, mutation(s) in at least one of the following positions are detected, i.e., the 194-, 199-, 324-, 1051-, 1084-, 1627-, 1685-, 1756-, 1853-, 2830-, 3371-, 4037- and 4364-positions.
摘要翻译:为了提供基于青光眼相关基因与青光眼发生之间的关系来预测青光眼的发病风险的基因检查方法,通过使用涉及代码的基因区域中的指示突变来预测未来的青光眼发作 区域和/或青光眼相关基因的上游区域。 在由SEQ ID NO:1表示的碱基序列中,检测至少一个以下位置的突变,即194-,199-,324-,1051-,1084-,1627-,1685- ,1756-,1853-,2830-,3371-4037-和4364-位。
摘要:
A noninvasive blood analyzer is provided which comprises: a light source for illuminating a part of tissues of a living body including a blood vessel; an image pickup section for picking up an image of the illuminated blood vessel and tissues; and an analyzing section for analyzing the picked image; the analyzing section including an extracting section for extracting image density distribution across the blood vessel in the image as an image density profile, a quantifying section for quantifying configurational characteristics of the image density profile, a computing section for computing the concentration of a blood constituent on the basis of the quantified characteristics, and an outputting section for outputting a computation result. The blood analyzer can measure the concentration of blood hemoglobin and the hematocrit in real time with an improved repeatability without blood sampling.
摘要:
A diagnostic support system for diabetes including an input device used for inputting diagnostic data including clinical testing data; a biological model having parameters and which represents a organ function related to diabetes as a numerical model; an predicting means for predicting parameter values suited for a patient based on the diagnostic data and the biological model; a pathological condition analyzing means for analyzing a diabetic pathological condition of a patient based on the parameter values predicted by the predicting means; a diagnostic support information generating means for generating diagnostic support information based on the analyzed pathological condition; and a diagnostic support information outputting means for outputting information obtained by the diagnostic support information generating means. A computer-readable storage medium is also disclosed.
摘要:
A cancer diagnosis supporting apparatus is provided with a memory for storing a predetermined reference value, a diagnosis support information preparer for preparing the diagnosis support information of cancer by comparing a measurement value obtained from a malignant tumor collected from a cancer patient and the reference value, and a change acceptor for accepting change of the reference value and for storing the changed reference value in the memory.