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    Device for detecting axis coplanarity of orthogonal rotary shafts having built-in intersection and precision detecting method
    12.
    发明授权
    Device for detecting axis coplanarity of orthogonal rotary shafts having built-in intersection and precision detecting method 有权
    用于检测具有内置交点的正交旋转轴的轴共面性的装置和精密检测方法

    公开(公告)号：US09212906B2

    公开(公告)日：2015-12-15

    申请号：US14352580

    申请日：2012-06-28

    申请人： Yumei Huang ,  Xingang Yang ,  Weigang Lv ,  Longfei Zhang ,  Tongqing Liu

    发明人： Yumei Huang ,  Xingang Yang ,  Weigang Lv ,  Longfei Zhang ,  Tongqing Liu

    IPC分类号： G01B21/24 ,  G01B5/012

    CPC分类号： G01B21/24 ,  G01B5/012

    摘要： The present invention discloses a device for detecting axis coplanarity of orthogonal rotary shafts having a built-in intersection, wherein a front assembly rotary body is coaxially connected on a front assembly housing, the front assembly rotary body and a rear assembly housing are fixedly connected with each other, the rear assembly rotary body is mounted in the rear assembly housing, a first three dimension movement fine tuning mechanism is mounted at an end of the rear assembly rotary body, the first three dimension movement fine tuning mechanism is connected with a standard sphere through a connecting rod, the three dimension movement fine tuning mechanisms are provided in the horizontal direction of the standard sphere and below the standard sphere in vertical direction, and two non-contact displacement sensors are mounted on said two three dimension movement fine tuning mechanisms respectively. The present invention also discloses a precision measurement method for measuring axis coplanarity of the orthogonal rotary shafts having a built-in intersection by using the above device, having a feature of high measurement precision, which is adaptive to coplanarity detections for the cantilever-type orthogonal shafts having a built-in intersection and the clamp-type orthogonal shafts having a built-in intersection.

    摘要翻译： 本发明公开了一种用于检测具有内置交点的正交旋转轴的轴共面性的装置，其中前组件旋转体同轴地连接在前组件壳体上，前组件旋转体和后组件壳体与 彼此相反，后组件旋转体安装在后组件壳体中，第一三维运动微调机构安装在后组件旋转体的一端，第一三维运动微调机构与标准球体 通过连杆，三维运动微调机构在标准球体的水平方向和标准球体的垂直方向下方设置，两个非接触位移传感器分别安装在所述两个三维运动微调机构上 。 本发明还公开了一种通过使用上述装置测量具有内置交点的正交旋转轴的轴线共面性的精密测量方法，具有高测量精度的特征，其适用于悬臂式正交的共平面检测 具有内置交叉的轴和具有内置交点的夹紧型正交轴。

    Biaxial linear-motion micro drive apparatus
    13.
    发明授权
    Biaxial linear-motion micro drive apparatus 有权
    双轴线性运动微驱动装置

    公开(公告)号：US09168623B2

    公开(公告)日：2015-10-27

    申请号：US13989850

    申请日：2011-10-13

    申请人： Yumei Huang ,  Hongyan Liu ,  Xingang Yang ,  Yong Yang

    发明人： Yumei Huang ,  Hongyan Liu ,  Xingang Yang ,  Yong Yang

    IPC分类号： G05G11/00 ,  B23Q5/22 ,  B23Q5/28

    CPC分类号： B23Q5/22 ,  B23Q5/28 ,  B23Q2210/002 ,  Y10T74/18992

    摘要： A biaxial linear-motion micro drive apparatus includes: a mounting base A on an upper surface of a Z-direction sliding base; a Z-direction micro actuator fixed within the mounting base A and connected with a Z-direction micro-motion platform connected with an X-direction sliding base; Z-direction guide rail strips arranged on the Z-direction sliding; two Z-direction guide rail blocks provided on one Z-direction guide rail strip fixedly mounted on a lower surface of the X-direction sliding base; a mounting base B provided on an upper surface of the X-direction sliding base; an X-direction micro actuator in the mounting base B and connected with an X-direction micro-motion platform connected with an XZ biaxial motion platform; two X-direction guide rail strips arranged on the upper surface of the X-direction sliding base; two X-direction guide rail blocks provided on each X-direction guide rail strip mounted on a lower surface of the XZ biaxial motion platform.

    摘要翻译： 双轴直线运动微驱动装置包括：在Z方向滑动基座的上表面上的安装基座A; 固定在安装基座A内并与与X方向滑动基座连接的Z方向微动平台连接的Z方向微致动器; Z方向导轨条布置在Z方向滑动; 设置在固定安装在X方向滑动基座的下表面上的一个Z方向导轨条上的两个Z方向导轨块; 设置在X方向滑动基座的上表面上的安装基座B; 安装基座B上的X方向微型致动器，与XZ双轴运动平台连接的X方向微动平台连接; 两个X方向导轨条布置在X方向滑动底座的上表面上; 设置在安装在XZ双轴运动平台的下表面上的每个X方向导轨条上的两个X方向导轨块。

    DEVICE FOR DETECTING AXIS COPLANARITY OF ORTHOGONAL ROTARY SHAFTS HAVING BUILT-IN INTERSECTION AND PRECISION DETECTING METHOD
    14.
    发明申请
    DEVICE FOR DETECTING AXIS COPLANARITY OF ORTHOGONAL ROTARY SHAFTS HAVING BUILT-IN INTERSECTION AND PRECISION DETECTING METHOD 有权
    用于检测具有内置接口和精密检测方法的正交旋转轴的轴对称性的装置

    公开(公告)号：US20140298668A1

    公开(公告)日：2014-10-09

    申请号：US14352580

    申请日：2012-06-28

    申请人： Yumei Huang ,  Xingang Yang ,  Weigang Lv ,  Longfei Zhang ,  Tongqing Liu

    发明人： Yumei Huang ,  Xingang Yang ,  Weigang Lv ,  Longfei Zhang ,  Tongqing Liu

    IPC分类号： G01B21/24

    CPC分类号： G01B21/24 ,  G01B5/012

    摘要： The present invention discloses a device for detecting axis coplanarity of orthogonal rotary shafts having a built-in intersection, wherein a front assembly rotary body is coaxially connected on a front assembly housing, the front assembly rotary body and a rear assembly housing are fixedly connected with each other, the rear assembly rotary body is mounted in the rear assembly housing, a first three dimension movement fine tuning mechanism is mounted at an end of the rear assembly rotary body, the first three dimension movement fine tuning mechanism is connected with a standard sphere through a connecting rod, the three dimension movement fine tuning mechanisms are provided in the horizontal direction of the standard sphere and below the standard sphere in vertical direction, and two non-contact displacement sensors are mounted on said two three dimension movement fine tuning mechanisms respectively. The present invention also discloses a precision measurement method for measuring axis coplanarity of the orthogonal rotary shafts having a built-in intersection by using the above device, having a feature of high measurement precision, which is adaptive to coplanarity detections for the cantilever-type orthogonal shafts having a built-in intersection and the clamp-type orthogonal shafts having a built-in intersection.

    摘要翻译： 本发明公开了一种用于检测具有内置交叉点的正交旋转轴的轴共面性的装置，其中前组件旋转体同轴地连接在前组件壳体上，前组件旋转体和后组件壳体固定连接 彼此相反，后组件旋转体安装在后组件壳体中，第一三维运动微调机构安装在后组件旋转体的一端，第一三维运动微调机构与标准球体 通过连杆，三维运动微调机构在标准球体的水平方向和标准球体的垂直方向下方设置，两个非接触位移传感器分别安装在所述两个三维运动微调机构上 。 本发明还公开了一种通过使用上述装置测量具有内置交点的正交旋转轴的轴线共面性的精密测量方法，具有高测量精度的特征，其适用于悬臂式正交的共平面检测 具有内置交叉的轴和具有内置交点的夹紧型正交轴。

    MACRO-MICRO ACTUATED DISTENDED GUIDE RAIL PRECISION ROTATION APPARATUS
    17.
    发明申请
    MACRO-MICRO ACTUATED DISTENDED GUIDE RAIL PRECISION ROTATION APPARATUS 有权
    大型微动导向导轨精密旋转装置

    公开(公告)号：US20150122058A1

    公开(公告)日：2015-05-07

    申请号：US14241935

    申请日：2012-02-06

    申请人： Yumei Huang ,  Manzhi Yang ,  Xingang Yang ,  Wenfeng Hou ,  Weigang Lv ,  Tongqing Liu ,  Guangpeng Zhang

    发明人： Yumei Huang ,  Manzhi Yang ,  Xingang Yang ,  Wenfeng Hou ,  Weigang Lv ,  Tongqing Liu ,  Guangpeng Zhang

    IPC分类号： B23Q5/28 ,  F16H21/16 ,  B23Q5/22

    CPC分类号： B23Q5/28 ,  B23Q1/34 ,  B23Q1/522 ,  B23Q5/22 ,  F16H21/16 ,  Y10T74/18056

    摘要： A macro-micro actuated distended guide rail precision rotation apparatus, having a housing of a torque motor and a bearing housing, both fixedly arranged on an upper surface of a base, and a bearing sleeved on the bearing housing. The inner ring of the bearing sleevingly connected to an intermediate rotating body connected to a bearing inner ring cap. A grating is provided at a lower end of the bearing inner ring cap. A connecting piece is arranged on the upper surface of the housing of the torque motor. The lower end of the connecting piece is fixedly connected to a rotary shaft of the torque motor. The connecting piece and the intermediate rotating body are both connected to the lower end of a fine movement mechanism fixedly connected to a rotary worktable. The rotation apparatus allows for highly precise macro-and-micro linked control, and for rotation control of great rotation range.

    摘要翻译： 一种具有转矩马达和轴承壳体的壳体的微型微型致动膨胀导轨精密旋转装置，两者均固定地设置在基座的上表面上，以及套在轴承壳体上的轴承。 轴承的内圈套筒连接到与轴承内圈盖连接的中间旋转体。 在轴承内圈盖的下端设有格栅。 连接件设置在扭矩电动机壳体的上表面上。 连接件的下端与转矩电动机的旋转轴固定连接。 连接件和中间旋转体都连接到固定连接到旋转工作台的微动机构的下端。 旋转装置允许高度精确的宏观和微观联动控制，以及大旋转范围的旋转控制。

    CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS
    19.
    发明申请
    CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS 审中-公开
    用于研究蛋白质 - 蛋白质相互作用的交联试剂，方法和组合物

    公开(公告)号：US20120322978A1

    公开(公告)日：2012-12-20

    申请号：US13579198

    申请日：2011-03-01

    申请人： Yumei Huang

    发明人： Yumei Huang

    IPC分类号： C07D229/02 ,  C07D403/12 ,  C07K5/10

    CPC分类号： C07D403/12 ,  C07D229/02 ,  C07K4/00 ,  C07K5/06086

    摘要： The invention provides reagents, methods, and compositions for studying protein-protein interactions. The inventive system and methods allow the analysis of protein-protein interactions in vivo and in vitro. Advantages offered by various embodiments of the inventive system and methods compared to existing photocrosslinking approaches include, for example, (i) novel reversible crosslinking reagents that allow easy isolation, purification, and enrichment of the crosslinked products; (ii) trifluoromethyl phenyldiazirine- or perfluorinated phenylazide-based photocrosslinking reagents that provide high specific labeling, no side product, and higher photocrosslinking efficiency; (iii) versatile spacer groups that allow systematic contact site mapping; (iv) novel methods for isolating, purifying, and detecting crosslinked products based on the reversible-link chemistry; and (v) the ability to study the interaction sites in vitro, in situ, or in vivo.

    摘要翻译： 本发明提供用于研究蛋白质 - 蛋白质相互作用的试剂，方法和组合物。 本发明的系统和方法允许在体内和体外分析蛋白质 - 蛋白质相互作用。 与现有光交联方法相比，本发明系统和方法的各种实施方案提供的优点包括例如（i）新颖的可逆交联试剂，其允许容易地分离，纯化和富集交联产物; （ii）提供高特异性标记，无副产物和更高光交联效率的三氟甲基苯基二氮丙腈或全氟化苯偶氮基光交联试剂; （iii）多功能间隔基，允许系统的接触位点作图; （iv）基于可逆链接化学分离，纯化和检测交联产物的新方法; 和（v）在体外，原位或体内研究相互作用位点的能力。