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公开(公告)号：US11555860B2
公开(公告)日：2023-01-17
申请号：US17301894
申请日：2021-04-19
发明人： Weiling Luan , Ying Chen , Senming Wu , Haofeng Chen
IPC分类号： G01R31/00 , G01R31/392 , H01M10/04 , H01M10/0525 , H01M10/0569 , H01M10/42
摘要： A method for testing a mechanical performance of a lithium ion battery electrode based on a nano-indentation technology includes following steps: connecting an assembled lithium ion battery with an electrochemical test device and setting different test working conditions, so that cyclic charge and discharge experiments are performed on the battery to obtain an attenuation curve of a battery capacity; disassembling the battery and taking out the electrode; scraping some powder from a surface of the cyclic electrode plate and an initial uncyclic electrode plate, and laying down the powder in cold mounting molds separately, pouring the cold mounting solution into the molds; taking out the samples from the molds respectively after the liquid is completely cured and cooled; detecting a mechanical performance after polishing the samples surfaces and analyzing the mechanical performance decay rule of the electrodes.
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公开(公告)号：US20220335443A1
公开(公告)日：2022-10-20
申请号：US17311378
申请日：2020-10-12
发明人： Weihong Zhu , Zhigang Zheng , Huijun Li , Honglong HU
摘要： The present disclosure discloses a novel multi-stable and erasable anti-counterfeiting technology with controlled reflection color and the application thereof in optical coding. The method and use are characterized by high thermal stability and robust fatigue resistance, and the realization thereof relies on the material system composed of an intrinsic chiral diarylethene molecule based on steric hindrance ethene bridge and a liquid crystal (LC) material disclosed herein. The diarylethene based on steric hindrance ethene bridge has the following structural feature: The material system composed of a diarylethene compound based on steric hindrance ethene bridge and an LC can be prepared by a simple preparation process from cheap raw materials, can achieve a wide spectral color adjustment range, and has excellent thermal stability and fatigue resistance, which is expected to be further widely used in the fields of dual erasable anti-counterfeiting and optical information encoding with high thermal stability and strong fatigue resistance.
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公开(公告)号：US11274988B2
公开(公告)日：2022-03-15
申请号：US16236399
申请日：2018-12-29
发明人： Fuzhen Xuan
摘要： The disclosure relates to a dual-criterion diagram for designing and assessing the life and strength of high-temperature rotating components and its establishment. In addition, the disclosure relates to a method for designing and assessing the life and strength of high-temperature rotating components based on the dual-criterion diagram for designing and assessing the life and strength of high-temperature rotating components. The advantages of the disclosure include a simple design and assessment process, high operability, and reliable assessment results. The invention is expected to be applied finally to assessment and evaluation of high-cycle fatigue life of rotating components at high temperatures.
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公开(公告)号：US11001866B2
公开(公告)日：2021-05-11
申请号：US16620529
申请日：2017-10-25
摘要： A strain of Burkholderia is Burkholderia glathei ECU0712, with an accession number of CGMCC NO. 14464. With the strain or its extract as the biocatalyst, thioether is catalyzed to be oxidized asymmetrically to chiral sulfoxide, with significant advantages that the obtained product has a high optical purity, and benefits of a simple reaction system, short preparation time of the catalyst and a high yield of the product.
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公开(公告)号：US10948467B2
公开(公告)日：2021-03-16
申请号：US16642531
申请日：2018-05-30
发明人： Daqi Gao , Xiaoqin Zhang , Zejian Wang , Liming Zhao
摘要： Provided is an online centralized monitoring and analysis system using an electronic nose instrument for multi-point malodorous gases, and the system includes an electronic nose instrument, which connects with multiple monitoring points through pipes. On-site malodorous gases in the maximum range of 2.5 km are drawn into the electronic nose instrument within 1 min by the external vacuum pump, and forced to flow through an annular working chamber of a gas sensor array for 30 s by the internal vacuum pump periodically. The modular convolution neural networks online learn the recent time-series responses of the gas sensor array and predict their coming responses, and the modular deep neural networks offline set up the relationship between the responses and multiple concentration items according to odor big data. The electronic nose instrument monitors up to 10 pollution sites cyclically and uses the cascade machine learning model to online predict one dimensionless odor-unit (OU) concentration index value and 10 specified-component concentration index values of malodorous gases.
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公开(公告)号：US10919869B2
公开(公告)日：2021-02-16
申请号：US16302564
申请日：2017-05-17
发明人： Honglin Li , Yufang Xu , Rui Wang , Zhenjiang Zhao , Wenlin Song , Liuxin Xu
IPC分类号： C07D277/50 , A61P19/02 , A61P37/00 , A61P33/00 , A61K31/426 , A61P35/00 , A61P17/06 , A61P31/04
摘要： A thiazole derivative serving as a DHODH inhibitor, and applications thereof. The present invention specifically relates to a compound represented by formula I, a pharmaceutical composition containing the compound represented by formula (I), and applications of the compound in the preparation of drugs for treating diseases mediated by the DHODH or drugs for inhibiting the DHODH.
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公开(公告)号：US20200140830A1
公开(公告)日：2020-05-07
申请号：US16620525
申请日：2018-04-13
摘要： A Bradyrhizobium monooxygenase, a gene for encoding the monooxygenase, a recombinant expression vector comprising the gene and a recombinant transformant, a method of preparing the monooxygenase by the recombinant expression transformant, and a method of preparing an optically pure chiral sulfoxide by the monooxygenase, in particular to a method of preparing prazole drugs by means of catalyzing the asymmetric oxidation of thioether, a prazole precursor. As compared with other methods of preparing an optically pure sulfoxide, the product produced by the monooxygenase of the present invention as a catalyst has high optical purity, avoids the generation of the byproduct sulfone, and has advantages of mild reaction conditions, simple and convenient operations, easy amplification, etc.
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公开(公告)号：US20190241584A1
公开(公告)日：2019-08-08
申请号：US16318762
申请日：2017-07-18
发明人： Linyong Zhu , Yi Yang , Dasheng Zhang , Zengmin Du , Bingkun Bao , Qiuning Lin , Yan Li , Xianjun Chen , Lipeng Yang , Chunyan Bao
IPC分类号： C07D495/04 , C07D333/78 , C07D495/14 , C09B57/00 , G01N33/68 , C12Q1/68 , G01N33/533 , C09B23/04 , C09B23/01
CPC分类号： C07D495/04 , A61K49/00 , C07D333/60 , C07D333/78 , C07D495/14 , C09B23/0058 , C09B23/0091 , C09B23/04 , C09B57/00 , C09K11/06 , C12Q1/68 , G01N33/533 , G01N33/68
摘要： Provided are a fluorescent dye and a preparation process and use thereof. The fluorescent dye is able to emit a long wavelength, is sensitive and specific to viscosity, and is used for a wide range of purposes, such as viscosity testing, fluorescent labeling, quantification or detection of proteins, enzymes or nucleic acids. In addition, it can be used as a fluorescent-activated probe.
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公开(公告)号：US10351891B2
公开(公告)日：2019-07-16
申请号：US15535274
申请日：2014-12-12
发明人： Fengqing Wang , Dongzhi Wei , Liqin Xu , Haohao Liu , Xinbin Liu , Nenghui Chen
摘要： The present invention provides a hydroxyacyl-coenzyme A dehydrogenase gene, an acyl-coenzyme A thiolase gene, genetically engineered strains and a use thereof. The hydroxyacyl-coenzyme A dehydrogenase gene encodes a protein (i) or (ii) as follows: (i) having an amino acid sequence according to SEQ ID NO 2; (ii) derived by substituting, deleting or inserting one or more amino acids in the amino acid sequence defined by (i) and having the same function as that of the protein of (i). The present invention constructs genetically engineered Mycobacterium strains lacking of a hydroxyacyl-coenzyme A dehydrogenase gene or an acyl-coenzyme A thiolase gene, which are used in the preparation of steroidal compounds, such as 1,4-BNA, 4-BNA, 9-OH-BNA, etc. Further, the invention improves the production efficiency and product quality of steroidal drug, improves the utilization of drug precursors, reduces the production costs, and provides the advantages of mild reaction conditions, environmentally friendly, and high economic and social benefits.
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公开(公告)号：US10071910B2
公开(公告)日：2018-09-11
申请号：US15033002
申请日：2013-10-31
发明人： Chongjun Zhao , Jianbo Dong , Youfu Huang , Jingwei Ma , Xiuzhen Qian
CPC分类号： C01B32/15 , B01J13/0052 , C01B32/00 , C01B32/05 , C01P2004/64 , C01P2006/12 , C01P2006/16
摘要： Methods described herein generally relate to producing carbon aerogel. The method may include providing a carbon-containing polymeric material, and contacting the carbon-containing polymeric material with light, heat or both to produce the carbon aerogel. Systems and kits for producing carbon aerogel are also disclosed.
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