公开(公告)号：US20220032245A1

公开(公告)日：2022-02-03

申请号：US17504328

申请日：2021-10-18

Applicant: South Dakota Board of Regents

Inventor： Ilchgerel Dash ,  Robb M. Winter

IPC: B01F7/00 ,  B01F15/06 ,  B82Y40/00 ,  B01F3/14 ,  B29C48/80 ,  C08J3/20 ,  C08J5/00

Abstract: An improved a device and method for dispersion and simultaneous orientation of nanoparticles within a matrix is provided. A mixer having a shaft and a stator is provided. The shaft may have a rupture region and erosion region. Further, an orienter having an angled stationary plate and a moving plate are provided. The nanoparticles and the matrix are fed into the mixer. A rotational force is applied to the shaft to produce shearing forces. The shearing forces disperse and exfoliate the nanoparticles within the matrix. The dispersed mixture is outputted onto the moving plate. The moving plate is forced across the angled stationary plate to produce fully developed laminar shear flow. The fully developed laminar shear flow or the two-dimensional extensional drag flow orients the dispersed nanoparticles-matrix mixture.

公开(公告)号：US20210393639A1

公开(公告)日：2021-12-23

申请号：US17447101

申请日：2021-09-08

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： HUNTER MOYER ,  DANIEL HEGLUND

IPC: A61K31/522 ,  A61K47/44 ,  A61K33/06 ,  A61K31/655 ,  A61K31/5415 ,  A61P7/08

Abstract: The present disclosure relates to compositions and systems for improving tissue perfusion such that blood flow is increased, improving tissue healing time and reducing or eliminating tissue necrosis. In a preferred embodiment, the compositions comprise a phosphodiesterase inhibitor, a calcium channel blocker, a nitric oxide producer, and an α-adrenergic antagonist. Methods of making the compositions and using the compositions are also disclosed.

公开(公告)号：US20210388285A1

公开(公告)日：2021-12-16

申请号：US17146396

申请日：2021-01-11

Applicant: Novum Nano, LLC ,  South Dakota Board of Regents

Inventor： Craig Bailey ,  Greg Christensen ,  Haiping Hong

IPC: C10M169/04 ,  C10M125/02 ,  C10M125/26

Abstract: An engine oil additive includes carbon nanotubes and boron nitride particulates dispersed within a fluid. The additive is configured to be mixed with a quantity of oil such that the quantity of oil has a concentration from 0.05 to 0.5 grams of carbon nanotubes and of boron nitride particulates per quart of oil to improve the lubricity of the oil. The additive improves the horsepower and torque of the engine while reducing fuel consumption. The carbon nanotubes have an —OH functionalized exterior surface. The carbon nanotubes have a diameter from 1 nanometer to 50 nanometers and have a length from 1 micron to 1000 microns. The boron nitride particulates are hex-boron nitride structures having an average size from 30 nanometers to 500 nanometers.

公开(公告)号：US11175736B2

公开(公告)日：2021-11-16

申请号：US16189653

申请日：2018-11-13

Applicant: South Dakota Board of Regents

Inventor： Lee Baugh ,  Kelene Fercho

IPC: G06F3/01 ,  A61B3/14 ,  A61B3/11 ,  A61B3/00

Abstract: The disclosed apparatus, systems and methods relate to pupillary assisted communication systems, devices and methods. A classification algorithm such as a hybrid classification algorithm is utilized to utilize at least one pupillary-response sensing device and at least one non-pupillary response sensing device to generate and process subject data to improve feedback systems and improve non-verbal communication and stimulus-response operations systems.

公开(公告)号：US11029284B2

公开(公告)日：2021-06-08

申请号：US16270447

申请日：2019-02-07

Applicant: South Dakota Board of Regents

Inventor： Lowell Kolb ,  Charles Tolle ,  Nathan Williams ,  Jason Ash

IPC: G01N29/036 ,  G01N29/24 ,  G01N29/024

Abstract: A system for determining gas characteristics at high altitudes in embodiments of the present invention may have one or more of the following features: (a) a high-altitude balloon having one or more of the following features: (a) a balloon, (b) a balloonsat operably coupled to the balloon, (c) an air path chamber wherein gas at a high altitude can occupy the air path chamber, (d) a first speaker located on a substrate within the air path chamber, wherein the first speaker takes an electrical signal input and creates a first sound wave, and (e) a second speaker located on the substrate facing opposite of the first speaker located outside of the air path chamber, wherein the second speaker takes the electrical signal and creates a second sound wave.

公开(公告)号：US11013798B2

公开(公告)日：2021-05-25

申请号：US16086894

申请日：2017-03-21

Applicant: SOUTH DAKOTA BOARD OF REGENTS ,  FEDERAL UNIVERSITY OF SANTA MARIA

Inventor： Diego G. Diel ,  Eduardo F. Flores

IPC: A61K39/275 ,  C12N15/86 ,  A61K48/00 ,  A61K39/00

Abstract: The present invention is directed to novel vaccine delivery platform based on the Orf virus (ORFV) genome, which carry heterologous antigens, methods of making and methods of using the same for prevention of infections, diseases, and other conditions in animals.

公开(公告)号：US20210148503A1

公开(公告)日：2021-05-20

申请号：US16953237

申请日：2020-11-19

Applicant: South Dakota Board of Regents

Inventor： Hadi Fekrmandi ,  Phillip Hillard ,  Skye Rutan-Bedard

IPC: F16L55/34 ,  B62D57/032

Abstract: A modular pipe-crawling robot for in-pipe maintenance operations in aspects of the present disclosure may have one or more of the following features: (a) at least two locomotion modules, (b) each module has feet which can extend outward to grip a wall of a pipe while simultaneously reducing its length or disengaging its feet from the inner wall while increasing its length, (c) a gear mechanism built into mechanical linkage, wherein each module's feet are held perpendicular with respect to the inner wall of the pipe, and (d) a joint coupling the at least two modules.

公开(公告)号：US10921784B2

公开(公告)日：2021-02-16

申请号：US16312187

申请日：2017-06-21

Applicant: South Dakota Board of Regents

Inventor： Christian Widener ,  Victor Champagne ,  Robert Hrabe

IPC: G05B19/4155 ,  C23C24/04 ,  C22C38/08 ,  C22C38/02

Abstract: The present disclosure addresses limitations with methods, systems and processes for integrating multiple advanced technologies into a single automated manufacturing and repair cell. The methods, systems and processes of the present disclosure leverage unique software and hardware to configure a manufacturing cell that is capable of conducting process development and planning, dimensional analysis, pre-machining, surface preparation, cold spray (supersonic particle deposition), dust collection, helium recovery, and post machining in a single integrated manufacturing and repair cell.

公开(公告)号：US20200036038A1

公开(公告)日：2020-01-30

申请号：US16589429

申请日：2019-10-01

Applicant: South Dakota Board of Regents

Inventor： Alevtina Smirnova ,  Matthew Dondelinger ,  Joel Swanson

IPC: H01M10/0562 ,  H01M10/052

Abstract: The present disclosure relates to a manufacturing process of the solid-state glass-ceramic electrolytes, known in the art as antiperovskites. Specifically, the disclosure is focused on manufacturing of the solid-state electrolyte from the corresponding precursors directly on the active electrode surface of an electrochemical device, specifically anode or cathode of the lithium-ion or lithium metal batteries.

公开(公告)号：US10358569B2

公开(公告)日：2019-07-23

申请号：US14213350

申请日：2014-03-14

Applicant: South Dakota Board of Regents

Inventor： Jon Kellar ,  P. Stanley May ,  William Cross ,  Jeevan Meruga ,  Tyler Blumenthal

IPC: B41F17/00 ,  C09D11/50 ,  B42D25/382 ,  C09D11/037 ,  C09D11/322 ,  B41M3/14

Abstract: The present invention relates generally to using upconverting inks for producing highly-resolved patterns for, inter alia, security applications. More specifically, the present invention relates to the use of sols (inks) and printing processes that produce well-defined printed features consisting of polymers impregnated with luminescent upconversion nanocrystals. The patterns printed using such inks and processes may exhibit defined shapes, characters of text, and various other types of images.