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公开(公告)号：US20240342111A1
公开(公告)日：2024-10-17
申请号：US18761018
申请日：2024-07-01
Applicant: University of South Carolina
Inventor： Sajish Mathew
CPC classification number: A61K31/05 , A61K9/0053
Abstract: Described herein are mechanistic results showing that cis- and trans-RSV have opposite effects on TyrRS-regulated neuronal DNA repair and survival, mechanistically, only cis-RSV protected neurons against stress conditions by activating TyrRS-regulated neuronal DNA repair and resilient signaling; trans-RSV, conversely, facilitated the downregulation of TyrRS resulting in the accumulation of DNA damage and subsequent neurodegeneration. Knockdown of TyrRS blunted the neuroprotective effects of cis-RSV and exacerbated the neurotoxicity by trans-RSV, providing a potential molecular basis for the controversial effects of RSV in clinical studies. The disclosure also provides an oral dosage form comprising an amount of resveratrol comprising a therapeutically effective amount of cis-resveratrol and not more than 200 mg of trans-resveratrol.
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公开(公告)号：US20240331883A1
公开(公告)日：2024-10-03
申请号：US18610522
申请日：2024-03-20
Applicant: University of South Carolina
Inventor： Travis W. Knight
Abstract: Described herein are mobile nuclear micro-reactors, systems for same, as well as methods of making mobile nuclear micro-reactors in the hundreds of kilowatt range, scalable to higher powers, capable of operating, at least, ten years without refueling while designed to eliminate fuel resupply tails that have proven so costly in conflicts over the past two decades or more.
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公开(公告)号：US20240331443A1
公开(公告)日：2024-10-03
申请号：US18623120
申请日：2024-04-01
Applicant: University of South Carolina
Inventor： Qiang Zeng
CPC classification number: G06V40/172 , G06F21/44 , G06V20/17 , G06V20/41 , G06V40/168 , G06V40/174 , G06V40/67
Abstract: Described herein are systems and methods for secure and usable authentication techniques for drone delivery that leverages biometric information of faces, unlike traditional biometrics-based approaches, it does not need users to enroll their biometric information and is impervious to common drone attacks.
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公开(公告)号：US12082534B2
公开(公告)日：2024-09-10
申请号：US18101168
申请日：2023-01-25
Applicant: UNIVERSITY OF SOUTH CAROLINA
Inventor： Sourav Banerjee , Corey Leydig
Abstract: An autonomous all-terrain robot for agricultural industries is designed to install support stakes inground on plant beds while being able to self-navigate. Apparatus and method provide a robot having the ability to perform the actions of navigating between plant beds and to determine a precise location and depth to place each supporting stake. The purpose of the stakes is to support the plants with weak stems. Part of some planting processes require stakes to support a plant as it begins to grow. from a two- or three-week-old plant to a fully mature plant. The presently disclosed subject matter provides a machine that can aid in the planting process of both bell peppers and eggplants and similar crops, used to drive stakes into planting beds. The presently disclosed technology (such as specific robotic device or robot) can work 24/7, weather permitting, while providing an efficient and completely hands-free way to install stakes needed in the planting process.
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公开(公告)号：US12018894B2
公开(公告)日：2024-06-25
申请号：US16824777
申请日：2020-03-20
Applicant: University of South Carolina
Inventor： Chen Li , Jamil Khan , Xinyu Huang , Tanvir Farouk , Raikan Dawas , Wei Chang , Pengtao Wang , Mohammad Alwazzan , Guanghan Huang
CPC classification number: F28D15/046 , F28B1/06 , F28D15/0275 , F28D15/0283 , F28D15/043
Abstract: Sweating-boosted air cooled heat-pipe condensers employing a nanowick micro fin structure to form a sweating boosted heat dissipation system, wherein the nanowicks may be layered.
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Patent Agency Ranking
公开(公告)号：US12006550B2
公开(公告)日：2024-06-11
申请号：US17400308
申请日：2021-08-12
Applicant: University of South Carolina
Inventor： Wenbin Tan , Elaine G. Taine , Hui Wang , Vi Nguyen , Xiaoling Cao
IPC: C12Q1/6883 , C07K16/28
CPC classification number: C12Q1/6883 , C07K16/2896 , C07K2317/76 , C12Q2600/158
Abstract: Described herein are methods and systems using ADAM30 as a biomarker to help early diagnosis of congenital malformed vasculatures in children and which can also serve as a companion diagnostic biomarker for malformed vasculatures, as well as a subpopulation of cancer cells, wherein blockage of activity of ADAM30 by a neutralized antibody or inhibitor can be used as a treatment strategy for those ADAM30-positive vascular endothelial cells and cancer cells.
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公开(公告)号：US11994436B2
公开(公告)日：2024-05-28
申请号：US17051225
申请日：2019-04-08
Applicant: UNIVERSITY OF SOUTH CAROLINA
Inventor： Dimitrios Rizos
CPC classification number: G01L1/24 , B61L23/045 , G01M5/0025
Abstract: Methods of non-destructive rail analysis and evaluation for railroad tracks are provided. The methods can include capturing images of rails over time and at various temperatures. High-contrast patterns can be applied to or associated with a rail to facilitate image analysis. Rail neutral temperature (RNT), stress, strain, and curvature of the track can be determined using image correlation and regression analysis. A stereovision system may be used for rail neutral temperature measurements and for determining effects of a heating method. A non-contacting, nondestructive methodology for RNT and longitudinal rail stress measurements is based on stereo vision image acquisition and Digital Image Correlation (DIC) for acquiring the full field shape, deformation, and strain measurements taken during a thermal cycle. The thermal cycle can be natural or induced.
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公开(公告)号：US11988672B2
公开(公告)日：2024-05-21
申请号：US17102633
申请日：2020-11-24
Applicant: University of South Carolina
Inventor： Dev Karan , Seema Dubey
IPC: G01N33/68 , C07K16/24 , G01N33/50 , G01N33/574 , A61K39/00
CPC classification number: G01N33/6863 , C07K16/24 , G01N33/5044 , G01N33/5047 , A61K2039/505 , C07K2317/76 , G01N33/57415 , G01N2333/521
Abstract: Using expression of CC chemokine ligand (CCL24) to serve as an identification of a potential deriver of metastatic cancers and methods of detecting the presence of CCL24 to serve as a breast cancer diagnosis tool.
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公开(公告)号：US11969293B2
公开(公告)日：2024-04-30
申请号：US17702067
申请日：2022-03-23
Applicant: University of South Carolina , The United States Government as Represented by the Department of Veterans Affairs
Inventor： William M. Torres , Francis G. Spinale , Tarek M. Shazly
CPC classification number: A61B8/5223 , A61B8/0883 , A61B8/485 , G06T17/20 , G06T2210/41
Abstract: Methods and systems for utilizing myocardial strain imaging in an inverse framework to identify mechanical properties of the heart and to determine structural and functional milestones for the development and progression to heart failure.
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20.发明公开公开(公告)号：US20240133767A1
公开(公告)日：2024-04-25
申请号：US18304457
申请日：2023-04-20
Applicant: UNIVERSITY OF SOUTH CAROLINA
Inventor： PAUL ZIEHL , CASEY A. COLE
IPC: G01M7/02 , G06N3/0464
CPC classification number: G01M7/025 , G06N3/0464
Abstract: Method and apparatus detect structural damage of structures using Acoustic Emission (AE) sensors. Using our method, structures can be monitored in real-time to predict damage level. This damage level assessment can be used to plan repairs and restorations of structures. Application can be used with concrete, and also applied to other materials such as composites. Predictive AE models may be tuned for determining structural damage zones, with the method extendable into any number of zones. An algorithm may be used in conjunction with decision tree filtering to use AE to predict structural damage zones, with the system able to perform analysis in real-time.
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