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公开(公告)号：US11771727B2
公开(公告)日：2023-10-03
申请号：US17656554
申请日：2022-03-25
发明人： Ping Lin , Zixuan Lin
IPC分类号： A61K36/232 , A61K36/605 , A61K36/77 , A61K36/076 , A61K36/8945 , A61K36/8969 , A61K36/482 , A61K36/23 , A61K36/725 , A61K36/9068 , A61K36/54 , A61K36/752 , A61K36/254 , A61P25/20 , A61K36/185 , A61K36/07
CPC分类号： A61K36/232 , A61K36/07 , A61K36/076 , A61K36/185 , A61K36/23 , A61K36/254 , A61K36/482 , A61K36/54 , A61K36/605 , A61K36/725 , A61K36/752 , A61K36/77 , A61K36/8945 , A61K36/8969 , A61K36/9068 , A61P25/20 , A61K2236/15
摘要： The disclosure relates to a traditional Chinese medicine composition and product for improving sleep by balancing yin and yang, a method for making the same and use thereof, and belongs to the technical field of traditional Chinese medicine. The disclosure provides a traditional Chinese medicine composition for improving sleep by balancing yin and yang, which has reasonable compatibility of all herbal medicines, nourishes yin to suppress yang, tonifies blood and promotes blood, regulates qi and soothes the nerves, and has the functions of reconciling yin and yang and balancing qi and blood. The composition may fundamentally improve sleep quality, with an effective rate of 100%. At the same time, all the medicines in the prescription are raw materials of medicine food homology, which are safe and effective, not cause side effects and mental dependence on the human body, and may be taken for a long time.
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公开(公告)号：US11752106B2
公开(公告)日：2023-09-12
申请号：US17475622
申请日：2021-09-15
发明人： Eleni Dokou , Shahla Jamzad , John P. Caesar, Jr. , Majed Fawaz , Laura Das , Chong-Hui Gu , Patricia Nell Hurter , Meghna Jai Israni , Meghan M. Johnston , Dragutin Knezic , Andrew G. Kuzmission , HongRen Wang
IPC分类号： A61K9/20 , A61K9/14 , A61K9/16 , A61K9/48 , A61K31/47 , A61K47/02 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/38 , C07D215/56 , A61P1/10 , A61P1/16 , A61P1/18 , A61P3/00 , A61P3/06 , A61P3/10 , A61P3/12 , A61P5/00 , A61P5/14 , A61P5/16 , A61P5/18 , A61P7/00 , A61P7/04 , A61P7/10 , A61P7/12 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/02 , A61P13/12 , A61P15/08 , A61P15/10 , A61P17/00 , A61P19/08 , A61P19/10 , A61P21/00 , A61P21/02 , A61P21/04 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/28 , A61P27/02 , A61P27/04 , A61P29/00 , A61P31/10 , A61P35/00 , A61P37/06 , A61P37/08 , A61P43/00 , A61K47/00
CPC分类号： A61K9/205 , A61K9/143 , A61K9/145 , A61K9/146 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/2072 , A61K9/2077 , A61K9/485 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K31/47 , A61K47/02 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/38 , C07D215/56
摘要： The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.
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13.发明授权公开(公告)号：US11738035B2
公开(公告)日：2023-08-29
申请号：US18077876
申请日：2022-12-08
发明人： Derek John Londesbrough , Christopher Brown , Julian Scott Northen , Gillian Moore , Hemant Kashinath Patil , David E. Nichols , Megan Croal , Hans Åke Eriksson , George Goldsmith , Molly Tabitha Hickey , Shaun Hurley , Ekaterina Malievskaia , Lindsey Marwood , Drummond E-Wen Joe McCulloch , Laurie Emma Medhurst , Nathan Poulsen , Aslihan Selimbeyoglu , Anaïs Soula , Amanda Tan Shuxiang , Manon Cecile Elisabeth Veraart , Tobias Patrick Whelan , Lars Christian Wilde , Stephen Wright
IPC分类号： A61K31/675 , A61P25/00 , A61P25/20 , A61P25/28 , A61P25/22 , A61P25/04 , A61P25/08 , A61P25/16 , C07F9/572
CPC分类号： A61K31/675 , A61P25/00 , A61P25/04 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/22 , A61P25/28 , C07F9/5728 , C07B2200/13
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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公开(公告)号：US11701425B2
公开(公告)日：2023-07-18
申请号：US17469458
申请日：2021-09-08
发明人： Syed M. Shah , Christopher Diorio , Daniel Hassan , Fred Hassan
IPC分类号： A61K47/12 , A61K36/84 , A61K9/20 , A61K9/24 , A61P25/20 , A61P25/22 , A61K9/00 , A61K9/28 , A61K36/35 , A61K47/38
CPC分类号： A61K47/12 , A61K9/0053 , A61K9/209 , A61K9/2013 , A61K9/2054 , A61K9/2086 , A61K9/28 , A61K36/35 , A61K36/84 , A61K47/38 , A61P25/20 , A61P25/22
摘要： A valerian composition includes valerian and an acidifying agent blended together in a pharmaceutically acceptable hydrogel-forming polymer matrix. An expedited release portion of the dosage form includes 5% to 50% of the valerian and is effective to release the valerian therein within 2 hours from placement in a 0.1 N HCl solution. A sustained release portion of the dosage form includes the remainder of the valerian and is effective to release the valerian therein within 10 hours from placement in a phosphate buffer with a pH of 6.8.
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15.发明申请公开(公告)号：US20230124137A1
公开(公告)日：2023-04-20
申请号：US18077876
申请日：2022-12-08
发明人： Derek John LONDESBROUGH , Christopher BROWN , Julian Scott NORTHEN , Gillian MOORE , Hemant Kashinath PATIL , David E. NICHOLS , Megan CROAL , Hans Åke ERIKSSON , George GOLDSMITH , Molly Tabitha HICKEY , Shaun HURLEY , Ekaterina MALIEVSKAIA , Lindsey MARWOOD , Drummond E-Wen Joe MCCULLOCH , Laurie Emma MEDHURST , Nathan POULSEN , Aslihan SELIMBEYOGLU , Anaïs SOULA , Amanda Tan SHUXIANG , Manon Cecile Elisabeth VERAART , Tobias Patrick WHELAN , Lars Christian WILDE , Stephen WRIGHT
IPC分类号： A61K31/675 , A61P25/00 , A61P25/20 , A61P25/28 , A61P25/22 , A61P25/04 , A61P25/08 , A61P25/16 , C07F9/572
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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公开(公告)号：US11628174B1
公开(公告)日：2023-04-18
申请号：US17861070
申请日：2022-07-08
申请人： Jianmin Wang , Geping Cui
发明人： Jianmin Wang , Geping Cui
IPC分类号： A61K31/5517 , A61K31/445 , A61P25/20
摘要： Pharmaceutical compositions comprising ebastine and alprazolam are disclosed. Methods of using the pharmaceutical compositions for treating patients suffering from insomnia are also disclosed.
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公开(公告)号：US20230093235A1
公开(公告)日：2023-03-23
申请号：US17500780
申请日：2021-10-13
发明人： Robert M. Jones , Mariangela Urbano , Gary Brandt , David Hardick , Chris Knight , Jason Tierney
IPC分类号： C07D487/04 , A61P15/08 , A61P15/10 , A61P25/20 , A61P25/24 , A61P9/06 , A61P25/18 , A61P25/22 , C07D491/04 , C07D498/04
摘要： Compounds are provided that antagonize vasopressin receptors, particularly the V1a receptor products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof: wherein A, B, G, R1, R1b, R1c, R2 and X are as defined herein.
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公开(公告)号：US20230050605A1
公开(公告)日：2023-02-16
申请号：US17758839
申请日：2021-01-13
发明人： Noam SOBEL , Eva MISHOR , Yaara ENDEVELT-SHAPIRA , Shiri KARAGACH , Yaniv MAMA , Yigal SHARON
摘要： The present invention discloses uses of hexadecanal in managing stress.
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19.发明授权公开(公告)号：US11564935B2
公开(公告)日：2023-01-31
申请号：US17540962
申请日：2021-12-02
发明人： Derek John Londesbrough , Christopher Brown , Julian Scott Northen , Gillian Moore , Hemant Kashinath Patil , David E. Nichols , Megan Croal , Hans Åke Eriksson , George Goldsmith , Molly Tabitha Hickey , Shaun Hurley , Ekaterina Malievskaia , Lindsey Marwood , Drummond E-Wen Joe McCulloch , Laurie Emma Medhurst , Nathan Poulsen , Aslihan Selimbeyoglu , Anaïs Soula , Amanda Tan Shuxiang , Manon Cecile Elisabeth Veraart , Tobias Patrick Whelan , Lars Christian Wilde , Stephen Wright
IPC分类号： A61K31/675 , A61P25/00 , A61P25/20 , A61P25/28 , A61P25/22 , A61P25/04 , A61P25/08 , A61P25/16 , C07F9/572
摘要： The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
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公开(公告)号：US20230000829A1
公开(公告)日：2023-01-05
申请号：US17772374
申请日：2020-10-07
发明人： Makoto Katsube , Hiroshi Watanabe , Kenichi Wakabayashi , Norihito Murayama , Kosuke Suzuki , Yoshitaka Tatebayashi , Yoshiki Matsuda , Nobuyuki Ozawa , Takiko Shinozaki
IPC分类号： A61K31/4172 , A23L33/175 , A61P25/20
摘要： The present invention aims to provide a composition for sleep improvement, which contains a highly safe substance as an active ingredient, and a method of improving sleep. The present invention relates to, for example, a composition for sleep improvement, which contains L-ergothioneine or a salt thereof as an active ingredient.
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