公开(公告)号：US20160145493A1

公开(公告)日：2016-05-26

申请号：US14898315

申请日：2013-06-14

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Zhigang ZHENG ,  Chao WANG

IPC: C09K19/60 ,  C09K19/54 ,  C09K19/58

CPC classification number: C09K19/601 ,  C09K19/126 ,  C09K19/2028 ,  C09K19/54 ,  C09K19/542 ,  C09K19/544 ,  C09K19/586 ,  C09K19/60 ,  C09K2019/0437 ,  C09K2019/0448 ,  C09K2019/2078

Abstract: Disclosed are polarization-independent electro-optical compositions using dichroic-dye-doped polymer stabilized optically isotropic chiral liquid crystals. The isotropic phase of such compositions can be well maintained even if the temperature is below 0° C. The electro-optical performances of such compositions demonstrate large Kerr constants, fast response times, and large contrast ratios of the compositions. The power consumption and the cost of devices based on the compositions can be decreased substantially due to alignment-free and polarizer-free characteristics. The compositions can be used to generate low power consumption displays and other photonic devices.

Abstract translation: 公开了使用二色性染料掺杂聚合物稳定的光学各向同性手性液晶的与偏振无关的电光组合物。 即使温度低于0℃，这种组合物的各向同性相也能得到很好的保持。这些组合物的电光学性能表现出较高的克尔常数，快速的响应时间和组合物的较大对比度。 由于无对准和无偏振特性，基于组合物的功率消耗和器件的成本可以显着降低。 该组合物可用于产生低功耗显示器和其它光子器件。

公开(公告)号：US20160020040A1

公开(公告)日：2016-01-21

申请号：US14773216

申请日：2013-03-05

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Chongjun Zhao ,  Xiangmao Dong ,  Shudi Min ,  Zhuomin Zhang ,  Kun Wang ,  Jianbo Dong ,  Xiuzhen Qian ,  Xin Chen

IPC: H01G11/86

CPC classification number: H01G11/86 ,  C01B32/23

Abstract: Methods of making metal oxide-graphene composites are disclosed. The methods can include, for example, providing a composition including graphene oxide and at least one substrate, the composition being dispersed in a liquid medium. The methods can also include, for example, providing a composition including graphene oxide and at least one substrate, heating the composition, and cooling the composition. Compositions useful for performing the methods and composites obtained by the process are also disclosed.

Abstract translation: 公开了制备金属氧化物 - 石墨烯复合材料的方法。 所述方法可以包括例如提供包含氧化石墨烯和至少一种底物的组合物，所述组合物分散在液体介质中。 所述方法还可以包括例如提供包含氧化石墨烯和至少一种底物的组合物，加热组合物并冷却组合物。 还公开了用于执行通过该方法获得的方法和复合材料的组合物。

公开(公告)号：US20150337025A1

公开(公告)日：2015-11-26

申请号：US14653276

申请日：2013-12-05

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Changsheng LIU ,  Wanli XING ,  Jing WANG ,  Jiangchao QIAN ,  Jing LIANG

IPC: C07K14/51 ,  A61K9/00 ,  A61K38/18 ,  A61K31/664

CPC classification number: C07K14/51 ,  A61K9/0019 ,  A61K31/664 ,  A61K38/1875 ,  A61K38/193 ,  C07K2319/33

Abstract: Disclosed is the use of a fusion protein in drugs for stimulating differentiation of bone marrow mesenchymal stem cells to hematopoietic stem/progenitor cells, or drugs for proliferation of granulocyte hematopoietic progenitor cells. The fusion protein has a sequence as shown in SEQ ID NO: 2 or SEQ ID NO: 4. The drugs can be used for the prevention and/or treatment of (i) hematopoietic dysfunction caused by chemotherapy, (ii) hematopoietic dysfunction caused by radiotherapy, or (iii) leukopenia.

Abstract translation: 公开了在药物中使用融合蛋白来刺激骨髓间充质干细胞分化成造血干细胞/祖细胞或用于粒细胞造血祖细胞增殖的药物。 融合蛋白具有如SEQ ID NO：2或SEQ ID NO：4所示的序列。该药物可用于预防和/或治疗（i）由化疗引起的造血功能障碍，（ii）造血功能障碍引起的 放射治疗，或（iii）白细胞减少。

公开(公告)号：US20150126508A1

公开(公告)日：2015-05-07

申请号：US14400508

申请日：2013-04-02

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Honglin Li ,  Yufang Xu ,  Zhenjiang Zhao ,  Xiaofeng Liu ,  Wei Zhou ,  Fang Bai ,  Mengzhu Xue ,  Lei Zhang ,  Youli Zhang

IPC: C07D475/00

CPC classification number: C07D475/00 ,  C07D239/50

Abstract: Provided are a pteridine ketone derivative used as an EGFR, BLK, and FLT3 inhibitor and applications thereof. Specifically, provided are a compound of the following formula I, a pharmaceutical composition containing the compound of the formula I, and use of compound in preparing medicine for treating diseases mediated by EGFR, BLK, or FLT3 or inhibiting EGFR, BLK, and FLT3.

Abstract translation: 提供用作EGFR，BLK和FLT3抑制剂的蝶啶酮衍生物及其应用。 具体地，提供下式I的化合物，含有式I化合物的药物组合物，以及化合物在制备用于治疗由EGFR，BLK或FLT3介导的疾病或抑制EGFR，BLK和FLT3的疾病的药物中的用途。

公开(公告)号：US08758645B2

公开(公告)日：2014-06-24

申请号：US13666946

申请日：2012-11-01

Applicant: Infovision Optoelectronics (Kunshan) Co., Ltd. ,  East China University of Science and Technology

Inventor： Zhi-gang Zheng ,  Hai-feng Wang ,  Dong Shen

IPC: C09K19/20 ,  C09K19/52 ,  C09K19/30 ,  C09K19/06 ,  C09K19/00 ,  B01J19/12 ,  C01B31/00

CPC classification number: C09K19/0275 ,  C09K19/586 ,  C09K2019/0448 ,  C09K2019/2078

Abstract: A blue phase liquid crystal material includes a liquid crystal host, a chiral reagent and a stable polymer. The chiral reagent is R811. The stable polymer is formed by photo-polymerizing a first monomer and a second monomer. The first monomer is 2-ethylhexyl acrylate (2-EHA), and the second monomer is 2-methyl-1,4-bis{4-[3(-acrylate)propoxyl]benzoicacid}phenylester (PTPTP). The blue phase liquid crystal material has a blue phase temperature range widened to an extremely low temperature. A blue phase liquid crystal composition and a method for manufacturing the blue phase liquid crystal material by using the blue phase liquid crystal composition are also provided.

Abstract translation: 蓝相液晶材料包括液晶主体，手性试剂和稳定的聚合物。 手性试剂为R811。 通过光聚合第一单体和第二单体形成稳定的聚合物。 第一单体是丙烯酸2-乙基己酯（2-EHA），第二单体是2-甲基-1,4-双{4- [3（ - 丙烯酸酯）丙氧基]苯甲酸}苯酯（PTPTP）。 蓝相液晶材料的蓝相温度范围变宽到极低温度。 还提供蓝相液晶组合物和通过使用蓝相液晶组合物制造蓝相液晶材料的方法。

公开(公告)号：US20250043182A1

公开(公告)日：2025-02-06

申请号：US18579713

申请日：2023-10-13

Applicant: East China University of Science and Technology

Inventor： Zhigang ZHENG ,  Conglong YUAN ,  Jiajun CHEN ,  Yuxing ZHAN ,  Huixian LIU

IPC: C09K19/12 ,  C09K19/02 ,  C09K19/20

Abstract: Provided are a twist-bend nematic (NTB) LC dimer-based material and use thereof, and an LC-based cholesteric heliconical (CH) material and use thereof. The NTB LC dimer-based material is at least one selected from the group consisting of CBnCB, CBnOCB, and CBOnOCB, with n being a positive integer of 3 to 15. Based on ultra-stable properties of the material, the disclosure further provides the LC-based CH material, which uses the LC dimer-based material as a key raw material and integrates a conventional nematic LC monomer material and a chiral molecule.

公开(公告)号：US12213330B2

公开(公告)日：2025-01-28

申请号：US17630356

申请日：2021-04-28

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Shuai Gu ,  Lei Xing ,  Jianguo Yu

IPC: H10K30/88 ,  C09K11/02 ,  C09K11/08 ,  H10K71/00

Abstract: The disclosure provides a precursor solution, a perovskite solar cell and a preparation method thereof. The solute of the precursor solution includes a metal halide, the solvent of the precursor solution is an organic solvent, and the precursor solution contains nanobubbles, which have a diameter not more than 1000 nm, and the zeta potential of the precursor solution does not exceed-20 mV. The method of preparing the precursor solution includes: (1) preparing an organic solvent containing nanobubbles; (2) dissolving a solute in the organic solvent containing nanobubbles. The precursor solution of the disclosure has a very low zeta potential, and the nanobubbles can exist stably in the organic solvent(s) for up to one month. When comparing with traditional methods for preparing the precursor solution of the perovskite cells, the method for preparing the precursor solution of the disclosure can effectively improve the stability, reproducibility and solubility of the metal halide in the organic solvent(s).

公开(公告)号：US12151325B2

公开(公告)日：2024-11-26

申请号：US18681015

申请日：2023-04-10

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Xiancheng Zhang ,  Jiawei Wang ,  Lin Zhu ,  Shantung Tu ,  Kaiming Zhang ,  Zhaoxing Sun ,  Shuang Liu ,  Huayi Cheng ,  Junmiao Shi

IPC: B21B11/00 ,  B21B13/00 ,  B21B13/14 ,  B23P9/02 ,  C21D7/04 ,  C22F1/00 ,  C22F3/00

Abstract: A double-sided ultrasonic rolling cooperative strengthening system and a control method thereof are provided. The system includes a first mechanical arm subsystem, a second mechanical arm subsystem, a first ultrasonic rolling strengthening subsystem, a second ultrasonic rolling strengthening subsystem and a servo turntable (13); the servo turntable (13) is configured to fix a blade to be processed; the first ultrasonic rolling strengthening subsystem is provided at an end of the first mechanical arm subsystem; and the second ultrasonic rolling strengthening subsystem is provided at an end of the second mechanical arm subsystem. The way that the mechanical arm is equipped with an ultrasonic rolling strengthening device improves a degree of freedom of processing the blade, and the first mechanical arm subsystem, the second mechanical arm subsystem, the first ultrasonic rolling strengthening subsystem, the second ultrasonic rolling strengthening subsystem and the servo turntable (13) are provided to cooperate to realize double-sided processing.

公开(公告)号：US20240287027A1

公开(公告)日：2024-08-29

申请号：US18570511

申请日：2022-05-26

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Jianhong ZHAO ,  Dingding WANG ,  Wulin YANG ,  Jinming NIU ,  Jun ZHU ,  Weiting WU ,  Jie YU ,  Zhen SUN ,  Xiaoli XU

IPC: C07D401/12

CPC classification number: C07D401/12

Abstract: An efficient and economical method for synthesizing Fasudil hydrochloride includes the synthesis route starts with inexpensive and readily available ethylenediamine as the starting material, obtains intermediate tert butyl-(N-(2-aminoethyl)-5-isoquinoline sulfonamide) carbamate (5) through sulfonylation and Boc protection, and then obtains Fasudil hydrochloride through a stacking process, which includes four steps: nucleophilic substitution, deprotection, cyclization, and salt formation. The total yield of Fasudil hydrochloride (1) is 67.1%, with a purity of up to 99.94%. Compared with traditional processes, the route avoids the use of expensive homopiperazine and its derivatives as synthetic intermediates. The advantages of the process include cheap and easy to obtain raw materials, simple operation, low cost, environmental friendliness, and suitability for industrial production.

公开(公告)号：US12061078B2

公开(公告)日：2024-08-13

申请号：US17312543

申请日：2019-03-28

Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Xiancheng Zhang ,  Shuang Liu ,  Shulei Yao ,  Xumin Zhu ,  Kaiming Zhang ,  Yixin Liu ,  Yunfei Jia ,  Shantung Tu

IPC: G01B11/24 ,  B23Q17/09 ,  B23Q17/24 ,  G01B11/00

CPC classification number: G01B11/24 ,  B23Q17/098 ,  B23Q17/2457 ,  G01B11/002

Abstract: The present application provides an on-machine point cloud detection and compensation method for processing complex surfaces, which comprises: step S1, installing a detecting and scanning actuator on an ultrasonic rolling machine tool; step S2, installing a processed workpiece on the chuck which is scanned by the detecting and scanning actuator to obtain the point cloud data of the workpiece in a coordinate system of detecting and scanning actuator, which is converted into the point cloud data of the workpiece in a coordinate system of machine tool; step S3, processing the point cloud data of the workpiece in the coordinate system of machine tool; step S4, obtaining and compensating the shape error feature of the workpiece according to theoretical design data of the processed workpiece and processed point cloud data of the workpiece in the coordinate system of machine tool. The accuracy and efficiency of complex surface strengthening is improved in the present application.