公开(公告)号：US20050100934A1

公开(公告)日：2005-05-12

申请号：US10888313

申请日：2004-07-09

Applicant: Kevin Lee ,  Richard Axel ,  Walter Strapps ,  Gilad Barnea

Inventor： Kevin Lee ,  Richard Axel ,  Walter Strapps ,  Gilad Barnea

IPC: C12N20060101 ,  C12N15/85 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/68 ,  G01N33/94

CPC classification number: G01N33/6845 ,  C12N15/1055 ,  G01N33/9406 ,  G01N2333/726 ,  G01N2500/10

Abstract: The invention relates to a method for determining if a test compound, or a mix of compounds, modulates the interaction between two proteins of interest. The determination is made possible via the use of two recombinant molecules, one of which contains the first protein a cleavage site for a proteolytic molecules, and an activator of a gene. The second recombinant molecule includes the second protein and the proteolytic molecule. If the test compound binds to the first protein, a reaction is initiated whereby the activator is cleaved, and activates a reporter gene.

Abstract translation: 本发明涉及一种用于确定测试化合物或化合物混合物是否调节两种感兴趣的蛋白质之间的相互作用的方法。 通过使用两个重组分子，其中之一含有蛋白水解分子的切割位点和基因的活化剂，其中之一含有第一个蛋白质，可以进行测定。 第二重组分子包括第二蛋白质和蛋白水解分子。 如果测试化合物与第一种蛋白质结合，则开始反应，由此活化剂被切割，并激活报告基因。

公开(公告)号：US20050053933A1

公开(公告)日：2005-03-10

申请号：US10486781

申请日：2002-08-14

Applicant: Kevin Lee ,  Thuy-Ai Nguyen ,  Brian Kloss

Inventor： Kevin Lee ,  Thuy-Ai Nguyen ,  Brian Kloss

IPC: C12N15/09 ,  A01N63/02 ,  C07K14/435 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/68 ,  A01N25/00 ,  C07H21/04 ,  C12N5/06

CPC classification number: C07K14/43563

Abstract: The present invention relates to insect odorant receptor genes and methods for identifying odorant receptor genes. The invention provides nucleotide sequences of insect odorant receptor genes Or83b, amino acid sequences of their encoded proteins (including peptides or polypeptides), and related products and methods. The nucleic acids of the invention may be operatively linked to promoter sequences and transformed into host cells. Methods of production of an Or83b odorant receptor protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Antibodies to an Or83b odorant receptor protein, and derivatives and analogs thereof, are provided. Methods for identifying molecules that bind or modulate the activity of these Or83b odorant receptor genes are provided. Molecules found to bind or modulate the activity of Or83b genes may be formulated into pest control agents by providing a carrier. In a preferred embodiment, molecules that bind or modulate the activity of an Or83b gene form one species but not others is desired. Methods to modify the insect behaviour by modifying an insect Or83b odorant are also provided.

Abstract translation: 本发明涉及昆虫气味受体基因和鉴别加味剂受体基因的方法。 本发明提供昆虫气味受体基因Or83b，其编码蛋白质（包括肽或多肽）的氨基酸序列以及相关产物和方法的核苷酸序列。 本发明的核酸可以可操作地连接到启动子序列并转化到宿主细胞中。 提供了Or83b气味受体蛋白质的生产方法（例如，通过重组方法）及其衍生物和类似物。 提供了对Or83b加味剂受体蛋白质的抗体及其衍生物和类似物。 提供了用于鉴定结合或调节这些Or83b加味剂受体基因的活性的分子的方法。 发现结合或调节Or83b基因活性的分子可以通过提供载体来配制成害虫防治剂。 在优选的实施方案中，期望结合或调节Or83b基因的活性形成一种但不是其它物质的分子。 还提供了通过修改昆虫Or83b气味来改变昆虫行为的方法。

公开(公告)号：US06816945B2

公开(公告)日：2004-11-09

申请号：US09922430

申请日：2001-08-03

Applicant: Kenneth Michael Harris ,  Kevin Lee Kidney ,  Brian Dennis McKean

Inventor： Kenneth Michael Harris ,  Kevin Lee Kidney ,  Brian Dennis McKean

IPC: G06F1200

CPC classification number: G06F11/2089 ,  G06F12/0804 ,  G06F12/0866 ,  G06F12/0891

Abstract: A method and apparatus for quiescing a system storage device wherein cache lines associated with a system storage device to be quiesced are flushed using a stripe lock mechanism to find and flush cache data associated with the given system storage device. Dirty cache lines are associated with a stripe lock, and that stripe lock will be in the active state or the clearing state. The stripe locks are also maintained on a linked list per a system storage device. In the normal life cycle of a stripe lock, if the partner controller requests a lock over part of the extent of an active lock, the active lock will go to the clearing state. Data in the extent of the now clearing lock is flushed. For performing a quiesce, stripe locks for the given system storage device are set to clearing on a plurality of controllers, thus causing the flush. The quiesce mechanism then only needs to wait until stripe locks have been cleared for the system storage device.

公开(公告)号：US06812876B1

公开(公告)日：2004-11-02

申请号：US10642736

申请日：2003-08-19

Applicant: Kevin Lee Miller

Inventor： Kevin Lee Miller

IPC: H03M300

CPC classification number: H03M3/334 ,  H03M3/332 ,  H03M3/412 ,  H03M3/448 ,  H03M3/454

Abstract: An improved dither generation circuit and method for digital audio circuits generates pseudo-random numbers that are then interpreted as 2's complement numbers representing data points of a bipolar signal. The random number signal is high-pass filtered to reduce the energy contained in the audio band. The resulting dither signal is applied to the circuit in its main feedback loop and is effective to prevent idle tones. Because of its spectrally shaped characteristic this dither signal introduces less noise into the audio band of interest and thereby improves the overall signal-to-noise ratio of the audio circuit.

Abstract translation: 用于数字音频电路的改进的抖动产生电路和方法产生伪随机数，然后将其解释为表示双极性信号的数据点的2的补码。 随机数信号被高通滤波以减少包含在音频带中的能量。 所产生的抖动信号在其主反馈回路中被施加到电路，并且有效地防止空闲音调。 由于其频谱特性，该抖动信号将较少的噪声引入感兴趣的音频带，从而提高音频电路的整体信噪比。

公开(公告)号：US06808294B2

公开(公告)日：2004-10-26

申请号：US10273863

申请日：2002-10-18

Applicant: Bruce Raymond Pazula ,  Chen Changda ,  Kevin Lee Von Kluck

Inventor： Bruce Raymond Pazula ,  Chen Changda ,  Kevin Lee Von Kluck

IPC: F21V106

CPC classification number: F21V1/06

Abstract: A lampshade having an assembled state and a collapsed state includes a first ring, a second ring spaced apart from the first ring when the lampshade is in the assembled state, and a first fabric covering interconnecting the first and second rings. A third ring is located adjacent the first ring when the lampshade is in the assembled state. A plurality of supports are connected between the second ring and the third ring. Each support has a first end portion movably connected to the second ring and a second end portion movably connected to the third ring. The supports hold the second and third rings spaced from each other. The supports urge the third ring into engagement with the first ring thereby to hold the first ring spaced apart from the second ring.

Abstract translation: 具有组装状态和收缩状态的灯罩包括第一环，当灯罩处于组装状态时与第一环间隔开的第二环以及互连第一和第二环的第一织物覆盖物。 当灯罩处于组装状态时，第三环位于第一环附近。 多个支撑件连接在第二环和第三环之间。 每个支撑件具有可移动地连接到第二环的第一端部和可移动地连接到第三环的第二端部。 支撑件保持第二和第三环彼此间隔开。 支撑件促使第三环与第一环接合，从而将第一环保持与第二环间隔开。

公开(公告)号：USD494976S1

公开(公告)日：2004-08-24

申请号：US29189179

申请日：2003-09-02

Applicant: Kevin Lee

Designer： Kevin Lee

公开(公告)号：USD482475S1

公开(公告)日：2003-11-18

申请号：US29172936

申请日：2002-12-20

Applicant: Kevin Lee

Designer： Kevin Lee

公开(公告)号：US06586539B2

公开(公告)日：2003-07-01

申请号：US09863430

申请日：2001-05-24

Applicant: Eric Cassisa ,  Jean-Claude Chinh ,  Stephen Kevin Lee

Inventor： Eric Cassisa ,  Jean-Claude Chinh ,  Stephen Kevin Lee

IPC: C08F234

CPC classification number: C08F10/00 ,  C08F210/16 ,  C08F2400/02 ,  C08F2/002 ,  C08F2/40 ,  C08F2/34 ,  C08F2/00 ,  C08F4/651 ,  C08F4/025 ,  C08F4/6555 ,  C08F210/08

Abstract: A process for controlling a continuous fluidised bed reactor (co-)polymerisation process which comprises (1) withdrawing from the reactor a hot recycle stream containing a principal monomer and at least one other unreacted reactant, (2) cooling part or all of the recycle stream withdrawn from the reactor, and (3) recycling part or all of the cooled recycle stream containing the principal monomer and the unreacted reactant(s) through the polymerisation zone in the reactor in the presence of a polymerisation catalyst under reactive conditions, wherein the controlling process consists in maintaining at least one of the reactant gradients (Gri) within a range of values outside which sheeting or unstable operations would otherwise occur.

Abstract translation: 一种用于控制连续流化床反应器（共）聚合方法的方法，其包括（1）从反应器中排出含有主要单体和至少一种其它未反应的反应物的热循环流，（2）冷却部分或全部循环 从反应器中取出的物流，和（3）在反应条件下，在聚合催化剂存在下，将反应器中含有主要单体和未反应的反应物的部分或全部冷却循环物流循环通过聚合区，其中 控制过程包括将反应物梯度（Gri）中的至少一个保持在外部范围内的值，否则将在其之外发生片材或不稳定的操作。

公开(公告)号：US06566319B1

公开(公告)日：2003-05-20

申请号：US09478906

申请日：2000-01-07

Applicant: Jeffrey John Scheibel ,  Kevin Lee Kott ,  Thomas Anthony Cripe ,  Daniel Stedman Connor ,  James Charles Theophile Roger Burckett-St. Laurent

Inventor： Jeffrey John Scheibel ,  Kevin Lee Kott ,  Thomas Anthony Cripe ,  Daniel Stedman Connor ,  James Charles Theophile Roger Burckett-St. Laurent

IPC: C11D1700

CPC classification number: C07C303/08 ,  C07C303/06 ,  C11D1/22 ,  C11D11/04 ,  C07C309/31

Abstract: Cleaning compositions, especially laundry detergents and the like, comprising (i) modified alkylarylsulfonate surfactants, e.g., modified alkylbenzenesulfonates, which are the product of particular processes and (ii) cleaning adjuncts such as enzymes and bleaches. Processes for making the cleaning products, including processes comprising vinylidene olefin production, alkylation of arenes, sulfonation and domestic cleaning product formulation. VO production is used to introduce particular limited branching into an alpha-olefinic feedstock which, converted to dimer form, has from about 10 to about 16, preferably from about 12 to about 14 carbon atoms. Preferred processes maximize the amount of vinylidene olefin useful for detergent manufacture, and minimize deep internal olefin production. Further, an alkylation step, preferably having an internal isomer selectivity of from 0 to no more than about 40 is used, in which the VO monoalkylates arenes such as benzene, in presence of an alkylation catalyst preferably comprising an at least partially crystalline, porous zeolite-containing solid, the zeolite being at least partially acidic and having intermediate pore size. Preferred alkylation catalysts include at least partially dealuminized acidic mordenites.

Abstract translation: 清洁组合物，特别是衣物洗涤剂等，其包含（i）改性的烷基芳基磺酸盐表面活性剂，例如改性烷基苯磺酸盐，其是特定方法的产物和（ii）清洁助剂如酶和漂白剂。 用于制造清洁产品的方法，包括包含亚乙烯基烯烃生产，芳烃烷基化，磺化和家用清洁产品配方的方法。 VO生产用于将特定有限的支化物引入α-烯烃原料中，其转化为二聚体形式具有约10至约16个，优选约12至约14个碳原子。 优选的方法使用于洗涤剂制造的亚乙烯基烯烃的量最大化，并使内部烯烃的生产最小化。 此外，使用优选具有0至不大于约40的内部异构体选择性的烷基化步骤，其中在烷基化催化剂存在下，优选包含至少部分结晶的多孔沸石的VO单烷基化物芳烃如苯 所述沸石至少部分为酸性且具有中等孔径。 优选的烷基化催化剂包括至少部分脱铝的酸性丝光沸石。

公开(公告)号：US06539953B2

公开(公告)日：2003-04-01

申请号：US09852590

申请日：2001-05-10

Applicant: Kevin Lee

Inventor： Kevin Lee

IPC: B08B9093

CPC classification number: C23C16/4407 ,  B08B9/00

Abstract: A method and an apparatus for cleaning a heater bellow in a chemical vapor deposition chamber by utilizing a plug and a plug base specifically designed for such cleaning are disclosed. The apparatus consists of the plug and the plug base which can be advantageously mounted in a heater bellow for the filling of the bellow with an oxidizing fluid such as H2O2. After a suitable soaking period of the oxidizing fluid, the fluid is drained away and then deionized water is used to fill the bellow to rinse the bellow wall and to remove the oxidized compound of metal, such as WO3. During the soaking process by H2O2 or by deionized water, an inert gas such as argon may be purged through the fluid to improve its uniformity and to improve its interaction with the metal oxide deposition on the bellow wall.